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Protein

Recombination protein RecR

Gene

recR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri57 – 72C4-typeUniRule annotationAdd BLAST16

GO - Molecular functioni

GO - Biological processi

  • DNA recombination Source: UniProtKB-HAMAP
  • DNA synthesis involved in DNA repair Source: EcoliWiki
  • response to UV Source: EcoliWiki
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciEcoCyc:EG10834-MONOMER.
ECOL316407:JW0461-MONOMER.
MetaCyc:EG10834-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Recombination protein RecRUniRule annotation
Gene namesi
Name:recRUniRule annotation
Ordered Locus Names:b0472, JW0461
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10834. recR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001903161 – 201Recombination protein RecRAdd BLAST201

Proteomic databases

EPDiP0A7H6.
PaxDbiP0A7H6.
PRIDEiP0A7H6.

Interactioni

Protein-protein interaction databases

BioGridi4261966. 170 interactors.
DIPiDIP-341N.
IntActiP0A7H6. 5 interactors.
STRINGi511145.b0472.

Structurei

3D structure databases

ProteinModelPortaliP0A7H6.
SMRiP0A7H6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 176ToprimUniRule annotationAdd BLAST96

Sequence similaritiesi

Belongs to the RecR family.UniRule annotation
Contains 1 Toprim domain.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri57 – 72C4-typeUniRule annotationAdd BLAST16

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG4105F3K. Bacteria.
COG0353. LUCA.
HOGENOMiHOG000103272.
InParanoidiP0A7H6.
KOiK06187.
OMAiDVMAIEN.
PhylomeDBiP0A7H6.

Family and domain databases

Gene3Di3.40.50.140. 1 hit.
HAMAPiMF_00017. RecR. 1 hit.
InterProiIPR000093. DNA_Rcmb_RecR.
IPR023627. Rcmb_RecR.
IPR023628. Rcmb_RecR_C4-type_Zn.
IPR015967. Rcmb_RecR_CS.
IPR006171. Toprim_domain.
[Graphical view]
PfamiPF02132. RecR. 1 hit.
PF13662. Toprim_4. 1 hit.
[Graphical view]
SMARTiSM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF111304. SSF111304. 1 hit.
TIGRFAMsiTIGR00615. recR. 1 hit.
PROSITEiPS01300. RECR. 1 hit.
PS50880. TOPRIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0A7H6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTSPLLTQL MEALRCLPGV GPKSAQRMAF TLLQRDRSGG MRLAQALTRA
60 70 80 90 100
MSEIGHCADC RTFTEQEVCN ICSNPRRQEN GQICVVESPA DIYAIEQTGQ
110 120 130 140 150
FSGRYFVLMG HLSPLDGIGP DDIGLDRLEQ RLAEEKITEV ILATNPTVEG
160 170 180 190 200
EATANYIAEL CAQYDVEASR IAHGVPVGGE LEMVDGTTLS HSLAGRHKIR

F
Length:201
Mass (Da):21,963
Last modified:June 7, 2005 - v1
Checksum:iF527EE1C809E47E9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti32L → V in AAA23459 (PubMed:1698765).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15761 Genomic DNA. Translation: CAA33768.1.
M38777 Genomic DNA. Translation: AAA23459.1.
U82664 Genomic DNA. Translation: AAB40226.1.
U00096 Genomic DNA. Translation: AAC73574.1.
AP009048 Genomic DNA. Translation: BAE76251.1.
PIRiJU0106. BVECRR.
RefSeqiNP_415005.1. NC_000913.3.
WP_001195025.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73574; AAC73574; b0472.
BAE76251; BAE76251; BAE76251.
GeneIDi945100.
KEGGiecj:JW0461.
eco:b0472.
PATRICi32116101. VBIEscCol129921_0492.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15761 Genomic DNA. Translation: CAA33768.1.
M38777 Genomic DNA. Translation: AAA23459.1.
U82664 Genomic DNA. Translation: AAB40226.1.
U00096 Genomic DNA. Translation: AAC73574.1.
AP009048 Genomic DNA. Translation: BAE76251.1.
PIRiJU0106. BVECRR.
RefSeqiNP_415005.1. NC_000913.3.
WP_001195025.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A7H6.
SMRiP0A7H6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261966. 170 interactors.
DIPiDIP-341N.
IntActiP0A7H6. 5 interactors.
STRINGi511145.b0472.

Proteomic databases

EPDiP0A7H6.
PaxDbiP0A7H6.
PRIDEiP0A7H6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73574; AAC73574; b0472.
BAE76251; BAE76251; BAE76251.
GeneIDi945100.
KEGGiecj:JW0461.
eco:b0472.
PATRICi32116101. VBIEscCol129921_0492.

Organism-specific databases

EchoBASEiEB0827.
EcoGeneiEG10834. recR.

Phylogenomic databases

eggNOGiENOG4105F3K. Bacteria.
COG0353. LUCA.
HOGENOMiHOG000103272.
InParanoidiP0A7H6.
KOiK06187.
OMAiDVMAIEN.
PhylomeDBiP0A7H6.

Enzyme and pathway databases

BioCyciEcoCyc:EG10834-MONOMER.
ECOL316407:JW0461-MONOMER.
MetaCyc:EG10834-MONOMER.

Miscellaneous databases

PROiP0A7H6.

Family and domain databases

Gene3Di3.40.50.140. 1 hit.
HAMAPiMF_00017. RecR. 1 hit.
InterProiIPR000093. DNA_Rcmb_RecR.
IPR023627. Rcmb_RecR.
IPR023628. Rcmb_RecR_C4-type_Zn.
IPR015967. Rcmb_RecR_CS.
IPR006171. Toprim_domain.
[Graphical view]
PfamiPF02132. RecR. 1 hit.
PF13662. Toprim_4. 1 hit.
[Graphical view]
SMARTiSM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF111304. SSF111304. 1 hit.
TIGRFAMsiTIGR00615. recR. 1 hit.
PROSITEiPS01300. RECR. 1 hit.
PS50880. TOPRIM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECR_ECOLI
AccessioniPrimary (citable) accession number: P0A7H6
Secondary accession number(s): P12727, Q2MBV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: November 30, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.