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Protein

DNA repair protein RecO

Gene

recO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in DNA repair and RecF pathway recombination.

GO - Biological processi

Keywordsi

Biological processDNA damage, DNA recombination, DNA repair

Enzyme and pathway databases

BioCyciEcoCyc:EG10832-MONOMER.
MetaCyc:EG10832-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA repair protein RecO
Alternative name(s):
Recombination protein O
Gene namesi
Name:recO
Ordered Locus Names:b2565, JW2549
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10832. recO.

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002049491 – 242DNA repair protein RecOAdd BLAST242

Proteomic databases

PaxDbiP0A7H3.
PRIDEiP0A7H3.

Expressioni

Inductioni

Encoded in the rnc-era-recO operon.

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

BioGridi4259430. 175 interactors.
DIPiDIP-48093N.
IntActiP0A7H3. 8 interactors.
STRINGi511145.b2565.

Structurei

Secondary structure

1242
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 14Combined sources11
Beta strandi16 – 18Combined sources3
Beta strandi20 – 26Combined sources7
Turni27 – 29Combined sources3
Beta strandi30 – 36Combined sources7
Turni37 – 40Combined sources4
Helixi46 – 49Combined sources4
Beta strandi56 – 61Combined sources6
Beta strandi63 – 75Combined sources13
Helixi84 – 99Combined sources16
Helixi107 – 121Combined sources15
Helixi128 – 142Combined sources15
Beta strandi148 – 150Combined sources3
Turni152 – 154Combined sources3
Beta strandi163 – 167Combined sources5
Turni168 – 170Combined sources3
Beta strandi171 – 174Combined sources4
Beta strandi182 – 184Combined sources3
Helixi185 – 193Combined sources9
Helixi199 – 213Combined sources15
Helixi214 – 216Combined sources3
Helixi223 – 229Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3Q8DX-ray2.30A/B1-242[»]
ProteinModelPortaliP0A7H3.
SMRiP0A7H3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecO family.Curated

Phylogenomic databases

eggNOGiENOG41071DT. Bacteria.
COG1381. LUCA.
HOGENOMiHOG000245560.
InParanoidiP0A7H3.
KOiK03584.
PhylomeDBiP0A7H3.

Family and domain databases

HAMAPiMF_00201. RecO. 1 hit.
InterProiView protein in InterPro
IPR022572. DNA_rep/recomb_RecO_N.
IPR012340. NA-bd_OB-fold.
IPR003717. RecO.
PfamiView protein in Pfam
PF02565. RecO_C. 1 hit.
PF11967. RecO_N. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00613. reco. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A7H3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGWQRAFVL HSRPWSETSL MLDVFTEESG RVRLVAKGAR SKRSTLKGAL
60 70 80 90 100
QPFTPLLLRF GGRGEVKTLR SAEAVSLALP LSGITLYSGL YINELLSRVL
110 120 130 140 150
EYETRFSELF FDYLHCIQSL AGVTGTPEPA LRRFELALLG HLGYGVNFTH
160 170 180 190 200
CAGSGEPVDD TMTYRYREEK GFIASVVIDN KTFTGRQLKA LNAREFPDAD
210 220 230 240
TLRAAKRFTR MALKPYLGGK PLKSRELFRQ FMPKRTVKTH YE
Length:242
Mass (Da):27,391
Last modified:June 7, 2005 - v1
Checksum:iD21C242C2F842D74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26416 Genomic DNA. Translation: AAA21842.1.
M27251 Genomic DNA. Translation: AAA24515.1.
D64044 Genomic DNA. Translation: BAA10912.1.
M76470 Genomic DNA. Translation: AAA21844.1.
U36841 Genomic DNA. Translation: AAA79827.1.
U00096 Genomic DNA. Translation: AAC75618.1.
AP009048 Genomic DNA. Translation: BAE76741.1.
M74526 Genomic DNA. No translation available.
PIRiJS0116. BVECRO.
RefSeqiNP_417060.1. NC_000913.3.
WP_000399404.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75618; AAC75618; b2565.
BAE76741; BAE76741; BAE76741.
GeneIDi947038.
KEGGiecj:JW2549.
eco:b2565.
PATRICifig|1411691.4.peg.4169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26416 Genomic DNA. Translation: AAA21842.1.
M27251 Genomic DNA. Translation: AAA24515.1.
D64044 Genomic DNA. Translation: BAA10912.1.
M76470 Genomic DNA. Translation: AAA21844.1.
U36841 Genomic DNA. Translation: AAA79827.1.
U00096 Genomic DNA. Translation: AAC75618.1.
AP009048 Genomic DNA. Translation: BAE76741.1.
M74526 Genomic DNA. No translation available.
PIRiJS0116. BVECRO.
RefSeqiNP_417060.1. NC_000913.3.
WP_000399404.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3Q8DX-ray2.30A/B1-242[»]
ProteinModelPortaliP0A7H3.
SMRiP0A7H3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259430. 175 interactors.
DIPiDIP-48093N.
IntActiP0A7H3. 8 interactors.
STRINGi511145.b2565.

Proteomic databases

PaxDbiP0A7H3.
PRIDEiP0A7H3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75618; AAC75618; b2565.
BAE76741; BAE76741; BAE76741.
GeneIDi947038.
KEGGiecj:JW2549.
eco:b2565.
PATRICifig|1411691.4.peg.4169.

Organism-specific databases

EchoBASEiEB0825.
EcoGeneiEG10832. recO.

Phylogenomic databases

eggNOGiENOG41071DT. Bacteria.
COG1381. LUCA.
HOGENOMiHOG000245560.
InParanoidiP0A7H3.
KOiK03584.
PhylomeDBiP0A7H3.

Enzyme and pathway databases

BioCyciEcoCyc:EG10832-MONOMER.
MetaCyc:EG10832-MONOMER.

Miscellaneous databases

PROiPR:P0A7H3.

Family and domain databases

HAMAPiMF_00201. RecO. 1 hit.
InterProiView protein in InterPro
IPR022572. DNA_rep/recomb_RecO_N.
IPR012340. NA-bd_OB-fold.
IPR003717. RecO.
PfamiView protein in Pfam
PF02565. RecO_C. 1 hit.
PF11967. RecO_N. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00613. reco. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRECO_ECOLI
AccessioniPrimary (citable) accession number: P0A7H3
Secondary accession number(s): P15027, P76589, Q2MAG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: June 7, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.