Reviewed, UniProtKB/Swiss-Prot P0A7H3 (RECO_ECOLI)

Names and origin

Protein names

Recommended name:
    DNA repair protein recO
Alternative name(s):
    Recombination protein O

Gene names

Name:	recO
Ordered Locus Names:	b2565, JW2549

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Involved in DNA repair and recF pathway recombination. HAMAP MF_00201
Subunit structure	Monomer. Ref.6
Sequence similarities	Belongs to the recO family.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair
Technical term	Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological process	DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	DNA repair protein recO HAMAP MF_00201		PRO_0000204949

Sequences

	Sequence		Length	Mass (Da)
	P0A7H3-1 [UniParc]. Last modified June 7, 2005. Version 1. Checksum: D21C242C2F842D74	FASTA	242	27,391
	10 20 30 40 50 60 MEGWQRAFVL HSRPWSETSL MLDVFTEESG RVRLVAKGAR SKRSTLKGAL QPFTPLLLRF 70 80 90 100 110 120 GGRGEVKTLR SAEAVSLALP LSGITLYSGL YINELLSRVL EYETRFSELF FDYLHCIQSL 130 140 150 160 170 180 AGVTGTPEPA LRRFELALLG HLGYGVNFTH CAGSGEPVDD TMTYRYREEK GFIASVVIDN 190 200 210 220 230 240 KTFTGRQLKA LNAREFPDAD TLRAAKRFTR MALKPYLGGK PLKSRELFRQ FMPKRTVKTH YE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genetic analysis of the rnc operon of Escherichia coli." Takiff H.E., Chen S.M., Court D.L. J. Bacteriol. 171:2581-2590(1989) [PubMed: 2540151] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Molecular analysis of the Escherichia coli recO gene." Morrison P.T., Lovett S.T., Gilson L.E., Kolodner R. J. Bacteriol. 171:3641-3649(1989) [PubMed: 2544549] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	Nashimoto H., Saito N. Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[4]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[5]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[6]	"Purification and characterization of the Escherichia coli RecO protein. Renaturation of complementary single-stranded DNA molecules catalyzed by the RecO protein." Luisi-DeLuca C., Kolodner R. J. Mol. Biol. 236:124-138(1994) [PubMed: 8107098] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-14, SUBUNIT.
[7]	"Suppression of insertions in the complex pdxJ operon of Escherichia coli K-12 by lon and other mutations." Lam H.-M., Tancula E., Dempsey W.B., Winkler M.E. J. Bacteriol. 174:1554-1567(1992) [PubMed: 1537800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 225-242. Strain: K12.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M26416 Genomic DNA. Translation: AAA21842.1. M27251 Genomic DNA. Translation: AAA24515.1. D64044 Genomic DNA. Translation: BAA10912.1. M76470 Genomic DNA. Translation: AAA21844.1. U36841 Genomic DNA. Translation: AAA79827.1. U00096 Genomic DNA. Translation: AAC75618.1. AP009048 Genomic DNA. Translation: BAE76741.1. M74526 Genomic DNA. No translation available.
PIR	BVECRO. JS0116.
RefSeq	AP_003151.1. NP_417060.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P0A7H3.
Genome annotation databases
GeneID	947038.
GenomeReviews	Gene locus JW2549 in contig AP009048_GR. Gene locus b2565 in contig U00096_GR.
KEGG	ecj:JW2549. eco:b2565.
Organism-specific databases
EchoBASE	EB0825.
EcoGene	EG10832. recO.
CMR	Search...
Phylogenomic databases
HOGENOM	P0A7H3.
OMA	RLMRQAL.
Enzyme and pathway databases
BioCyc	EcoCyc:EG10832-MON. MetaCyc:EG10832-MON.
Gene expression databases
Genevestigator	P0A7H3.
Family and domain databases
HAMAP	MF_00201. [Tree]
InterPro	IPR003717. RecO. [Graphical view]
Pfam	PF02565. RecO. 1 hit. [Graphical view]
TIGRFAMs	TIGR00613. reco. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RECO_ECOLI

Accession

Primary (citable) accession number: P0A7H3
Secondary accession number(s): P15027, P76589, Q2MAG5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	June 7, 2005
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)