Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein NrdI

Gene

nrdI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Probably involved in ribonucleotide reductase function.By similarity

GO - Molecular functioni

  • FMN binding Source: EcoCyc

GO - Biological processi

  • cellular protein modification process Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7402-MONOMER.
ECOL316407:JW2649-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NrdI
Gene namesi
Name:nrdI
Synonyms:ygaO
Ordered Locus Names:b2674, JW2649
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13287. nrdI.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001643141 – 136Protein NrdIAdd BLAST136

Proteomic databases

PaxDbiP0A772.
PRIDEiP0A772.

Expressioni

Inductioni

Induced 2-fold by hydroxyurea.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262268. 9 interactors.
IntActiP0A772. 26 interactors.
STRINGi511145.b2674.

Structurei

Secondary structure

1136
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Helixi13 – 21Combined sources9
Beta strandi25 – 27Combined sources3
Beta strandi30 – 33Combined sources4
Beta strandi42 – 47Combined sources6
Beta strandi52 – 58Combined sources7
Helixi60 – 66Combined sources7
Helixi69 – 74Combined sources6
Beta strandi75 – 82Combined sources8
Helixi84 – 89Combined sources6
Helixi92 – 101Combined sources10
Beta strandi105 – 110Combined sources6
Helixi115 – 130Combined sources16

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3N39X-ray2.50C/D1-133[»]
3N3AX-ray1.99C/D1-133[»]
3N3BX-ray2.36C/D1-133[»]
ProteinModelPortaliP0A772.
SMRiP0A772.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A772.

Family & Domainsi

Sequence similaritiesi

Belongs to the NrdI family.Curated

Phylogenomic databases

eggNOGiENOG4105G3E. Bacteria.
COG1780. LUCA.
HOGENOMiHOG000246177.
InParanoidiP0A772.
KOiK03647.
OMAiNTHRFVG.
PhylomeDBiP0A772.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_00128. NrdI. 1 hit.
InterProiIPR029039. Flavoprotein-like_dom.
IPR020852. RNR_Ib_NrdI_bac.
IPR004465. RNR_NrdI.
[Graphical view]
PfamiPF07972. Flavodoxin_NdrI. 1 hit.
[Graphical view]
PIRSFiPIRSF005087. NrdI. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR00333. nrdI. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A772-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLVYFSSS SENTQRFIER LGLPAVRIPL NERERIQVDE PYILIVPSYG
60 70 80 90 100
GGGTAGAVPR QVIRFLNDEH NRALLRGVIA SGNRNFGEAY GRAGDVIARK
110 120 130
CGVPWLYRFE LMGTQSDIEN VRKGVTEFWQ RQPQNA
Length:136
Mass (Da):15,340
Last modified:June 7, 2005 - v1
Checksum:i2834D808D18EBCBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79787 Genomic DNA. Translation: CAA56185.1.
U00096 Genomic DNA. Translation: AAC75721.1.
AP009048 Genomic DNA. Translation: BAA16538.2.
PIRiS70890.
RefSeqiNP_417160.1. NC_000913.3.
WP_000080947.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75721; AAC75721; b2674.
BAA16538; BAA16538; BAA16538.
GeneIDi947158.
KEGGiecj:JW2649.
eco:b2674.
PATRICi32120738. VBIEscCol129921_2766.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79787 Genomic DNA. Translation: CAA56185.1.
U00096 Genomic DNA. Translation: AAC75721.1.
AP009048 Genomic DNA. Translation: BAA16538.2.
PIRiS70890.
RefSeqiNP_417160.1. NC_000913.3.
WP_000080947.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3N39X-ray2.50C/D1-133[»]
3N3AX-ray1.99C/D1-133[»]
3N3BX-ray2.36C/D1-133[»]
ProteinModelPortaliP0A772.
SMRiP0A772.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262268. 9 interactors.
IntActiP0A772. 26 interactors.
STRINGi511145.b2674.

Proteomic databases

PaxDbiP0A772.
PRIDEiP0A772.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75721; AAC75721; b2674.
BAA16538; BAA16538; BAA16538.
GeneIDi947158.
KEGGiecj:JW2649.
eco:b2674.
PATRICi32120738. VBIEscCol129921_2766.

Organism-specific databases

EchoBASEiEB3072.
EcoGeneiEG13287. nrdI.

Phylogenomic databases

eggNOGiENOG4105G3E. Bacteria.
COG1780. LUCA.
HOGENOMiHOG000246177.
InParanoidiP0A772.
KOiK03647.
OMAiNTHRFVG.
PhylomeDBiP0A772.

Enzyme and pathway databases

BioCyciEcoCyc:G7402-MONOMER.
ECOL316407:JW2649-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0A772.
PROiP0A772.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_00128. NrdI. 1 hit.
InterProiIPR029039. Flavoprotein-like_dom.
IPR020852. RNR_Ib_NrdI_bac.
IPR004465. RNR_NrdI.
[Graphical view]
PfamiPF07972. Flavodoxin_NdrI. 1 hit.
[Graphical view]
PIRSFiPIRSF005087. NrdI. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR00333. nrdI. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNRDI_ECOLI
AccessioniPrimary (citable) accession number: P0A772
Secondary accession number(s): P77025, Q47415
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: November 2, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.