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Protein

Protein NrdI

Gene

nrdI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably involved in ribonucleotide reductase function.By similarity

GO - Molecular functioni

  • FMN binding Source: EcoCyc

GO - Biological processi

  • cellular protein modification process Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G7402-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NrdI
Gene namesi
Name:nrdI
Synonyms:ygaO
Ordered Locus Names:b2674, JW2649
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13287 nrdI

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001643141 – 136Protein NrdIAdd BLAST136

Proteomic databases

PaxDbiP0A772
PRIDEiP0A772

Expressioni

Inductioni

Induced 2-fold by hydroxyurea.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262268, 9 interactors
IntActiP0A772, 26 interactors
STRINGi316385.ECDH10B_2841

Structurei

Secondary structure

1136
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Helixi13 – 21Combined sources9
Beta strandi25 – 27Combined sources3
Beta strandi30 – 33Combined sources4
Beta strandi42 – 47Combined sources6
Beta strandi52 – 58Combined sources7
Helixi60 – 66Combined sources7
Helixi69 – 74Combined sources6
Beta strandi75 – 82Combined sources8
Helixi84 – 89Combined sources6
Helixi92 – 101Combined sources10
Beta strandi105 – 110Combined sources6
Helixi115 – 130Combined sources16

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3N39X-ray2.50C/D1-133[»]
3N3AX-ray1.99C/D1-133[»]
3N3BX-ray2.36C/D1-133[»]
ProteinModelPortaliP0A772
SMRiP0A772
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A772

Family & Domainsi

Sequence similaritiesi

Belongs to the NrdI family.Curated

Phylogenomic databases

eggNOGiENOG4105G3E Bacteria
COG1780 LUCA
HOGENOMiHOG000246177
InParanoidiP0A772
KOiK03647
OMAiIVYYSSA
PhylomeDBiP0A772

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_00128 NrdI, 1 hit
InterProiView protein in InterPro
IPR029039 Flavoprotein-like_sf
IPR020852 RNR_Ib_NrdI_bac
IPR004465 RNR_NrdI
PANTHERiPTHR37297 PTHR37297, 1 hit
PfamiView protein in Pfam
PF07972 Flavodoxin_NdrI, 1 hit
PIRSFiPIRSF005087 NrdI, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR00333 nrdI, 1 hit

Sequencei

Sequence statusi: Complete.

P0A772-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLVYFSSS SENTQRFIER LGLPAVRIPL NERERIQVDE PYILIVPSYG
60 70 80 90 100
GGGTAGAVPR QVIRFLNDEH NRALLRGVIA SGNRNFGEAY GRAGDVIARK
110 120 130
CGVPWLYRFE LMGTQSDIEN VRKGVTEFWQ RQPQNA
Length:136
Mass (Da):15,340
Last modified:June 7, 2005 - v1
Checksum:i2834D808D18EBCBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79787 Genomic DNA Translation: CAA56185.1
U00096 Genomic DNA Translation: AAC75721.1
AP009048 Genomic DNA Translation: BAA16538.2
PIRiS70890
RefSeqiNP_417160.1, NC_000913.3
WP_000080947.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75721; AAC75721; b2674
BAA16538; BAA16538; BAA16538
GeneIDi947158
KEGGiecj:JW2649
eco:b2674
PATRICifig|1411691.4.peg.4067

Similar proteinsi

Entry informationi

Entry nameiNRDI_ECOLI
AccessioniPrimary (citable) accession number: P0A772
Secondary accession number(s): P77025, Q47415
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health