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Protein

Ion-translocating oxidoreductase complex subunit A

Gene

rsxA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).UniRule annotation1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G6871-MONOMER

Protein family/group databases

TCDBi3.D.6.1.4 the putative ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family

Names & Taxonomyi

Protein namesi
Recommended name:
Ion-translocating oxidoreductase complex subunit AUniRule annotationCurated (EC:1.18.1.-UniRule annotationCurated)
Alternative name(s):
Rsx electron transport complex subunit AUniRule annotationCurated
Gene namesi
Name:rsxA1 PublicationUniRule annotation
Synonyms:rnfA, ydgL
Ordered Locus Names:b1627, JW1619
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13933 rsxA

Subcellular locationi

  • Cell inner membrane UniRule annotation1 Publication; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 4PeriplasmicCurated4
Transmembranei5 – 25HelicalUniRule annotationAdd BLAST21
Topological domaini26 – 38Cytoplasmic1 PublicationAdd BLAST13
Transmembranei39 – 59HelicalUniRule annotationAdd BLAST21
Topological domaini60 – 62Periplasmic1 Publication3
Transmembranei63 – 83HelicalUniRule annotationAdd BLAST21
Topological domaini84 – 101Cytoplasmic1 PublicationAdd BLAST18
Transmembranei102 – 122HelicalUniRule annotationAdd BLAST21
Topological domaini123 – 133Periplasmic1 PublicationAdd BLAST11
Transmembranei134 – 154HelicalUniRule annotationAdd BLAST21
Topological domaini155 – 170Cytoplasmic1 PublicationAdd BLAST16
Transmembranei171 – 191HelicalUniRule annotationAdd BLAST21
Topological domaini192 – 193Periplasmic2 Publications2

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002142891 – 193Ion-translocating oxidoreductase complex subunit AAdd BLAST193

Proteomic databases

PaxDbiP0A766
PRIDEiP0A766

Interactioni

Subunit structurei

The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.UniRule annotation1 Publication

Protein-protein interaction databases

BioGridi4261327, 41 interactors
STRINGi316385.ECDH10B_1761

Structurei

3D structure databases

ProteinModelPortaliP0A766
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NqrDE/RnfAE family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DGN Bacteria
COG4657 LUCA
HOGENOMiHOG000279324
InParanoidiP0A766
KOiK03617
OMAiEMFLKKS
PhylomeDBiP0A766

Family and domain databases

HAMAPiMF_00459 RsxA_RnfA, 1 hit
InterProiView protein in InterPro
IPR011293 Ion_transpt_RnfA/RsxA
IPR003667 NqrDE/RnfAE
PfamiView protein in Pfam
PF02508 Rnf-Nqr, 1 hit
PIRSFiPIRSF006102 NQR_DE, 1 hit
TIGRFAMsiTIGR01943 rnfA, 1 hit

Sequencei

Sequence statusi: Complete.

P0A766-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDYLLLFVG TVLVNNFVLV KFLGLCPFMG VSKKLETAMG MGLATTFVMT
60 70 80 90 100
LASICAWLID TWILIPLNLI YLRTLAFILV IAVVVQFTEM VVRKTSPVLY
110 120 130 140 150
RLLGIFLPLI TTNCAVLGVA LLNINLGHNF LQSALYGFSA AVGFSLVMVL
160 170 180 190
FAAIRERLAV ADVPAPFRGN AIALITAGLM SLAFMGFSGL VKL
Length:193
Mass (Da):20,898
Last modified:June 7, 2005 - v1
Checksum:i525955B3760398D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74699.1
AP009048 Genomic DNA Translation: BAE76486.1
PIRiE64919
RefSeqiNP_416144.1, NC_000913.3
WP_000133193.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74699; AAC74699; b1627
BAE76486; BAE76486; BAE76486
GeneIDi946148
KEGGiecj:JW1619
eco:b1627
PATRICifig|1411691.4.peg.634

Similar proteinsi

Entry informationi

Entry nameiRSXA_ECOLI
AccessioniPrimary (citable) accession number: P0A766
Secondary accession number(s): P76181, Q2MB70
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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