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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Shigella flexneri
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei71By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthase (EC:4.2.3.3)
Short name:
MGS
Gene namesi
Name:mgsA
Ordered Locus Names:SF0965, S1031
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Chemistry databases

DrugBankiDB02726. 2-Phosphoglycolic Acid.
DB01942. Formic Acid.
DB03026. Phosphoglycolohydroxamic Acid.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001786461 – 152Methylglyoxal synthaseAdd BLAST152

Proteomic databases

PaxDbiP0A733.

Interactioni

Subunit structurei

Homohexamer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP0A733.
SMRiP0A733.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.Curated

Phylogenomic databases

eggNOGiENOG4108Z5K. Bacteria.
COG1803. LUCA.
HOGENOMiHOG000283729.
KOiK01734.

Family and domain databases

CDDicd01422. MGS. 1 hit.
Gene3Di3.40.50.1380. 1 hit.
HAMAPiMF_00549. Methylglyoxal_synth. 1 hit.
InterProiView protein in InterPro
IPR004363. Methylgl_synth.
IPR018148. Methylglyoxal_synth_AS.
IPR011607. MGS-like_dom.
PfamiView protein in Pfam
PF02142. MGS. 1 hit.
PIRSFiPIRSF006614. Methylglyox_syn. 1 hit.
SMARTiView protein in SMART
SM00851. MGS. 1 hit.
SUPFAMiSSF52335. SSF52335. 1 hit.
TIGRFAMsiTIGR00160. MGSA. 1 hit.
PROSITEiView protein in PROSITE
PS01335. METHYLGLYOXAL_SYNTH. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A733-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELTTRTLPA RKHIALVAHD HCKQMLMSWV ERHQPLLEQH VLYATGTTGN
60 70 80 90 100
LISRATGMNV NAMLSGPMGG DQQVGALISE GKIDVLIFFW DPLNAVPHDP
110 120 130 140 150
DVKALLRLAT VWNIPVATNV ATADFIIQSP HFNDAVDILI PDYQRYLADR

LK
Length:152
Mass (Da):16,919
Last modified:June 7, 2005 - v1
Checksum:i85157193BD4CE72D
GO

Sequence cautioni

The sequence AAN42593 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAP16479 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN42593.1. Different initiation.
AE014073 Genomic DNA. Translation: AAP16479.1. Different initiation.
RefSeqiNP_706886.3. NC_004337.2.
WP_000424181.1. NZ_MSKG02000189.1.

Genome annotation databases

EnsemblBacteriaiAAN42593; AAN42593; SF0965.
AAP16479; AAP16479; S1031.
GeneIDi1023912.
KEGGisfl:SF0965.
sfx:S1031.
PATRICifig|198214.7.peg.1123.

Similar proteinsi

Entry informationi

Entry nameiMGSA_SHIFL
AccessioniPrimary (citable) accession number: P0A733
Secondary accession number(s): P37066
, P75872, Q8XD91, Q9R7Q3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: September 27, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families