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Protein

Probable intracellular septation protein A

Gene

yciB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in cell division; probably involved in intracellular septation.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Septation

Enzyme and pathway databases

BioCyciEcoCyc:EG11122-MONOMER.
ECOL316407:JW1246-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable intracellular septation protein AUniRule annotation
Gene namesi
Name:yciBUniRule annotation
Synonyms:ispZ
Ordered Locus Names:b1254, JW1246
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11122. yciB.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21PeriplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalUniRule annotationAdd BLAST21
Topological domaini43 – 49CytoplasmicSequence analysis7
Transmembranei50 – 70HelicalUniRule annotationAdd BLAST21
Topological domaini71 – 75PeriplasmicSequence analysis5
Transmembranei76 – 96HelicalUniRule annotationAdd BLAST21
Topological domaini97 – 120CytoplasmicSequence analysisAdd BLAST24
Transmembranei121 – 141HelicalUniRule annotationAdd BLAST21
Topological domaini142 – 148PeriplasmicSequence analysis7
Transmembranei149 – 169HelicalUniRule annotationAdd BLAST21
Topological domaini170 – 179CytoplasmicSequence analysis10

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002065311 – 179Probable intracellular septation protein AAdd BLAST179

Proteomic databases

PaxDbiP0A710.
PRIDEiP0A710.

Interactioni

Protein-protein interaction databases

BioGridi4262998. 140 interactors.
STRINGi511145.b1254.

Structurei

3D structure databases

ProteinModelPortaliP0A710.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YciB family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107835. Bacteria.
COG2917. LUCA.
HOGENOMiHOG000062588.
InParanoidiP0A710.
KOiK06190.
OMAiFWVNFKV.
PhylomeDBiP0A710.

Family and domain databases

HAMAPiMF_00189. Intracell_septation_prot_A. 1 hit.
InterProiIPR006008. Intracell_sepatation_prot_A.
[Graphical view]
PfamiPF04279. IspA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00997. ispZ. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A710-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQFLDFLPL VVFFAFYKIY DIYAATAALI VATAIVLIYS WVRFRKVEKM
60 70 80 90 100
ALITFVLVVV FGGLTLFFHN DEFIKWKVTV IYALFAGALL VSQWVMKKPL
110 120 130 140 150
IQRMLGKELT LPQPVWSKLN LAWAVFFILC GLANIYIAFW LPQNIWVNFK
160 170
VFGLTALTLI FTLLSGIYIY RHMPQEDKS
Length:179
Mass (Da):20,790
Last modified:June 7, 2005 - v1
Checksum:i6A52B2D9CA996EEF
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti99P → Q in strain: ECOR 31. 1
Natural varianti110T → M in strain: ECOR 28. 1
Natural varianti111L → V in strain: ECOR 60. 1
Natural varianti114P → S in strain: ECOR 52. 1
Natural varianti117S → L in strain: ECOR 28. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13583 Genomic DNA. Translation: CAA31924.1.
U24195 Genomic DNA. Translation: AAB60067.1.
U24196 Genomic DNA. Translation: AAB60075.1.
U24197 Genomic DNA. Translation: AAB60083.1.
U24198 Genomic DNA. Translation: AAB60091.1.
U24199 Genomic DNA. Translation: AAB60099.1.
U24200 Genomic DNA. Translation: AAB60107.1.
U24201 Genomic DNA. Translation: AAB60115.1.
U24202 Genomic DNA. Translation: AAB60123.1.
U24203 Genomic DNA. Translation: AAB60131.1.
U24204 Genomic DNA. Translation: AAB60139.1.
U24205 Genomic DNA. Translation: AAB60147.1.
U24206 Genomic DNA. Translation: AAB60155.1.
U00096 Genomic DNA. Translation: AAC74336.1.
AP009048 Genomic DNA. Translation: BAA14786.1.
PIRiS07799.
T45503.
RefSeqiNP_415770.1. NC_000913.3.
WP_000808667.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74336; AAC74336; b1254.
BAA14786; BAA14786; BAA14786.
GeneIDi946228.
KEGGiecj:JW1246.
eco:b1254.
PATRICi32117768. VBIEscCol129921_1304.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13583 Genomic DNA. Translation: CAA31924.1.
U24195 Genomic DNA. Translation: AAB60067.1.
U24196 Genomic DNA. Translation: AAB60075.1.
U24197 Genomic DNA. Translation: AAB60083.1.
U24198 Genomic DNA. Translation: AAB60091.1.
U24199 Genomic DNA. Translation: AAB60099.1.
U24200 Genomic DNA. Translation: AAB60107.1.
U24201 Genomic DNA. Translation: AAB60115.1.
U24202 Genomic DNA. Translation: AAB60123.1.
U24203 Genomic DNA. Translation: AAB60131.1.
U24204 Genomic DNA. Translation: AAB60139.1.
U24205 Genomic DNA. Translation: AAB60147.1.
U24206 Genomic DNA. Translation: AAB60155.1.
U00096 Genomic DNA. Translation: AAC74336.1.
AP009048 Genomic DNA. Translation: BAA14786.1.
PIRiS07799.
T45503.
RefSeqiNP_415770.1. NC_000913.3.
WP_000808667.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A710.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262998. 140 interactors.
STRINGi511145.b1254.

Proteomic databases

PaxDbiP0A710.
PRIDEiP0A710.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74336; AAC74336; b1254.
BAA14786; BAA14786; BAA14786.
GeneIDi946228.
KEGGiecj:JW1246.
eco:b1254.
PATRICi32117768. VBIEscCol129921_1304.

Organism-specific databases

EchoBASEiEB1112.
EcoGeneiEG11122. yciB.

Phylogenomic databases

eggNOGiENOG4107835. Bacteria.
COG2917. LUCA.
HOGENOMiHOG000062588.
InParanoidiP0A710.
KOiK06190.
OMAiFWVNFKV.
PhylomeDBiP0A710.

Enzyme and pathway databases

BioCyciEcoCyc:EG11122-MONOMER.
ECOL316407:JW1246-MONOMER.

Miscellaneous databases

PROiP0A710.

Family and domain databases

HAMAPiMF_00189. Intracell_septation_prot_A. 1 hit.
InterProiIPR006008. Intracell_sepatation_prot_A.
[Graphical view]
PfamiPF04279. IspA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00997. ispZ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYCIB_ECOLI
AccessioniPrimary (citable) accession number: P0A710
Secondary accession number(s): P21366
, P94721, P94725, P94735, P94738
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: November 30, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.