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Protein

Probable intracellular septation protein A

Gene

yciB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in cell division; probably involved in intracellular septation.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Septation

Enzyme and pathway databases

BioCyciEcoCyc:EG11122-MONOMER.
ECOL316407:JW1246-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable intracellular septation protein AUniRule annotation
Gene namesi
Name:yciBUniRule annotation
Synonyms:ispZ
Ordered Locus Names:b1254, JW1246
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11122. yciB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121PeriplasmicSequence analysisAdd
BLAST
Transmembranei22 – 4221HelicalUniRule annotationAdd
BLAST
Topological domaini43 – 497CytoplasmicSequence analysis
Transmembranei50 – 7021HelicalUniRule annotationAdd
BLAST
Topological domaini71 – 755PeriplasmicSequence analysis
Transmembranei76 – 9621HelicalUniRule annotationAdd
BLAST
Topological domaini97 – 12024CytoplasmicSequence analysisAdd
BLAST
Transmembranei121 – 14121HelicalUniRule annotationAdd
BLAST
Topological domaini142 – 1487PeriplasmicSequence analysis
Transmembranei149 – 16921HelicalUniRule annotationAdd
BLAST
Topological domaini170 – 17910CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 179179Probable intracellular septation protein APRO_0000206531Add
BLAST

Proteomic databases

PaxDbiP0A710.

Interactioni

Protein-protein interaction databases

BioGridi4262998. 140 interactions.
STRINGi511145.b1254.

Structurei

3D structure databases

ProteinModelPortaliP0A710.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YciB family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107835. Bacteria.
COG2917. LUCA.
HOGENOMiHOG000062588.
InParanoidiP0A710.
KOiK06190.
OMAiFWVNFKV.
OrthoDBiEOG6JHRJS.
PhylomeDBiP0A710.

Family and domain databases

HAMAPiMF_00189. Intracell_septation_prot_A.
InterProiIPR006008. Intracell_sepatation_prot_A.
[Graphical view]
PfamiPF04279. IspA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00997. ispZ. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A710-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQFLDFLPL VVFFAFYKIY DIYAATAALI VATAIVLIYS WVRFRKVEKM
60 70 80 90 100
ALITFVLVVV FGGLTLFFHN DEFIKWKVTV IYALFAGALL VSQWVMKKPL
110 120 130 140 150
IQRMLGKELT LPQPVWSKLN LAWAVFFILC GLANIYIAFW LPQNIWVNFK
160 170
VFGLTALTLI FTLLSGIYIY RHMPQEDKS
Length:179
Mass (Da):20,790
Last modified:June 7, 2005 - v1
Checksum:i6A52B2D9CA996EEF
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti99 – 991P → Q in strain: ECOR 31.
Natural varianti110 – 1101T → M in strain: ECOR 28.
Natural varianti111 – 1111L → V in strain: ECOR 60.
Natural varianti114 – 1141P → S in strain: ECOR 52.
Natural varianti117 – 1171S → L in strain: ECOR 28.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13583 Genomic DNA. Translation: CAA31924.1.
U24195 Genomic DNA. Translation: AAB60067.1.
U24196 Genomic DNA. Translation: AAB60075.1.
U24197 Genomic DNA. Translation: AAB60083.1.
U24198 Genomic DNA. Translation: AAB60091.1.
U24199 Genomic DNA. Translation: AAB60099.1.
U24200 Genomic DNA. Translation: AAB60107.1.
U24201 Genomic DNA. Translation: AAB60115.1.
U24202 Genomic DNA. Translation: AAB60123.1.
U24203 Genomic DNA. Translation: AAB60131.1.
U24204 Genomic DNA. Translation: AAB60139.1.
U24205 Genomic DNA. Translation: AAB60147.1.
U24206 Genomic DNA. Translation: AAB60155.1.
U00096 Genomic DNA. Translation: AAC74336.1.
AP009048 Genomic DNA. Translation: BAA14786.1.
PIRiS07799.
T45503.
RefSeqiNP_415770.1. NC_000913.3.
WP_000808667.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74336; AAC74336; b1254.
BAA14786; BAA14786; BAA14786.
GeneIDi946228.
KEGGiecj:JW1246.
eco:b1254.
PATRICi32117768. VBIEscCol129921_1304.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13583 Genomic DNA. Translation: CAA31924.1.
U24195 Genomic DNA. Translation: AAB60067.1.
U24196 Genomic DNA. Translation: AAB60075.1.
U24197 Genomic DNA. Translation: AAB60083.1.
U24198 Genomic DNA. Translation: AAB60091.1.
U24199 Genomic DNA. Translation: AAB60099.1.
U24200 Genomic DNA. Translation: AAB60107.1.
U24201 Genomic DNA. Translation: AAB60115.1.
U24202 Genomic DNA. Translation: AAB60123.1.
U24203 Genomic DNA. Translation: AAB60131.1.
U24204 Genomic DNA. Translation: AAB60139.1.
U24205 Genomic DNA. Translation: AAB60147.1.
U24206 Genomic DNA. Translation: AAB60155.1.
U00096 Genomic DNA. Translation: AAC74336.1.
AP009048 Genomic DNA. Translation: BAA14786.1.
PIRiS07799.
T45503.
RefSeqiNP_415770.1. NC_000913.3.
WP_000808667.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A710.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262998. 140 interactions.
STRINGi511145.b1254.

Proteomic databases

PaxDbiP0A710.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74336; AAC74336; b1254.
BAA14786; BAA14786; BAA14786.
GeneIDi946228.
KEGGiecj:JW1246.
eco:b1254.
PATRICi32117768. VBIEscCol129921_1304.

Organism-specific databases

EchoBASEiEB1112.
EcoGeneiEG11122. yciB.

Phylogenomic databases

eggNOGiENOG4107835. Bacteria.
COG2917. LUCA.
HOGENOMiHOG000062588.
InParanoidiP0A710.
KOiK06190.
OMAiFWVNFKV.
OrthoDBiEOG6JHRJS.
PhylomeDBiP0A710.

Enzyme and pathway databases

BioCyciEcoCyc:EG11122-MONOMER.
ECOL316407:JW1246-MONOMER.

Miscellaneous databases

PROiP0A710.

Family and domain databases

HAMAPiMF_00189. Intracell_septation_prot_A.
InterProiIPR006008. Intracell_sepatation_prot_A.
[Graphical view]
PfamiPF04279. IspA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00997. ispZ. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular evolution of the Escherichia coli chromosome. I. Analysis of structure and natural variation in a previously uncharacterized region between trp and tonB."
    Stoltzfus A., Leslie J.F., Milkman R.
    Genetics 120:345-358(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Milkman R.
    Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 and Various ECOR strains.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  5. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYCIB_ECOLI
AccessioniPrimary (citable) accession number: P0A710
Secondary accession number(s): P21366
, P94721, P94725, P94735, P94738
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: April 13, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.