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Protein

Probable intracellular septation protein A

Gene

yciB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in cell division; probably involved in intracellular septation.UniRule annotation

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Septation

Enzyme and pathway databases

BioCyciEcoCyc:EG11122-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable intracellular septation protein AUniRule annotation
Gene namesi
Name:yciBUniRule annotation
Synonyms:ispZ
Ordered Locus Names:b1254, JW1246
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11122 yciB

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 21PeriplasmicSequence analysisAdd BLAST21
Transmembranei22 – 42HelicalUniRule annotationAdd BLAST21
Topological domaini43 – 49CytoplasmicSequence analysis7
Transmembranei50 – 70HelicalUniRule annotationAdd BLAST21
Topological domaini71 – 75PeriplasmicSequence analysis5
Transmembranei76 – 96HelicalUniRule annotationAdd BLAST21
Topological domaini97 – 120CytoplasmicSequence analysisAdd BLAST24
Transmembranei121 – 141HelicalUniRule annotationAdd BLAST21
Topological domaini142 – 148PeriplasmicSequence analysis7
Transmembranei149 – 169HelicalUniRule annotationAdd BLAST21
Topological domaini170 – 179CytoplasmicSequence analysis10

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002065311 – 179Probable intracellular septation protein AAdd BLAST179

Proteomic databases

PaxDbiP0A710
PRIDEiP0A710

Interactioni

Protein-protein interaction databases

BioGridi4262998, 140 interactors
STRINGi316385.ECDH10B_1369

Structurei

3D structure databases

ProteinModelPortaliP0A710
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YciB family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107835 Bacteria
COG2917 LUCA
HOGENOMiHOG000062588
InParanoidiP0A710
KOiK06190
OMAiAWVNFKL
PhylomeDBiP0A710

Family and domain databases

HAMAPiMF_00189 Intracell_septation_prot_A, 1 hit
InterProiView protein in InterPro
IPR006008 Intracell_sepatation_prot_A
PANTHERiPTHR36917 PTHR36917, 1 hit
PfamiView protein in Pfam
PF04279 IspA, 1 hit
TIGRFAMsiTIGR00997 ispZ, 1 hit

Sequencei

Sequence statusi: Complete.

P0A710-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQFLDFLPL VVFFAFYKIY DIYAATAALI VATAIVLIYS WVRFRKVEKM
60 70 80 90 100
ALITFVLVVV FGGLTLFFHN DEFIKWKVTV IYALFAGALL VSQWVMKKPL
110 120 130 140 150
IQRMLGKELT LPQPVWSKLN LAWAVFFILC GLANIYIAFW LPQNIWVNFK
160 170
VFGLTALTLI FTLLSGIYIY RHMPQEDKS
Length:179
Mass (Da):20,790
Last modified:June 7, 2005 - v1
Checksum:i6A52B2D9CA996EEF
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti99P → Q in strain: ECOR 31. 1
Natural varianti110T → M in strain: ECOR 28. 1
Natural varianti111L → V in strain: ECOR 60. 1
Natural varianti114P → S in strain: ECOR 52. 1
Natural varianti117S → L in strain: ECOR 28. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13583 Genomic DNA Translation: CAA31924.1
U24195 Genomic DNA Translation: AAB60067.1
U24196 Genomic DNA Translation: AAB60075.1
U24197 Genomic DNA Translation: AAB60083.1
U24198 Genomic DNA Translation: AAB60091.1
U24199 Genomic DNA Translation: AAB60099.1
U24200 Genomic DNA Translation: AAB60107.1
U24201 Genomic DNA Translation: AAB60115.1
U24202 Genomic DNA Translation: AAB60123.1
U24203 Genomic DNA Translation: AAB60131.1
U24204 Genomic DNA Translation: AAB60139.1
U24205 Genomic DNA Translation: AAB60147.1
U24206 Genomic DNA Translation: AAB60155.1
U00096 Genomic DNA Translation: AAC74336.1
AP009048 Genomic DNA Translation: BAA14786.1
PIRiS07799
T45503
RefSeqiNP_415770.1, NC_000913.3
WP_000808667.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74336; AAC74336; b1254
BAA14786; BAA14786; BAA14786
GeneIDi946228
KEGGiecj:JW1246
eco:b1254
PATRICifig|1411691.4.peg.1029

Similar proteinsi

Entry informationi

Entry nameiYCIB_ECOLI
AccessioniPrimary (citable) accession number: P0A710
Secondary accession number(s): P21366
, P94721, P94725, P94735, P94738
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health