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Protein

Glycogen synthase

Gene

glgA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.By similarity

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15ADP-glucoseBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciECOO157:GLGA-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase (EC:2.4.1.21)
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene namesi
Name:glgA
Ordered Locus Names:Z4791, ECs4274
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001886131 – 477Glycogen synthaseAdd BLAST477

Interactioni

Protein-protein interaction databases

STRINGi155864.Z4791.

Structurei

3D structure databases

ProteinModelPortaliP0A6V0.
SMRiP0A6V0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CXW. Bacteria.
COG0297. LUCA.
HOGENOMiHOG000294941.
KOiK00703.
OMAiLLNAMRC.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth. 1 hit.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A6V0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDARVL LPAFPDIRRG
60 70 80 90 100
VTDAQVVSRR DTFAGHITLL FGHYNGVGIY LIDAPHLYDR PGSPYHDTNL
110 120 130 140 150
FAYTDNVLRF ALLGWVGAEM ASGLDPFWRP DVVHAHDWHA GLAPAYLAAR
160 170 180 190 200
GRPAKSVFTV HNLAYQGMFY AHHMNDIQLP WSFFNIHGLE FNGQISFLKA
210 220 230 240 250
GLYYADHITA VSPTYAREIT EPQFAYGMEG LLQQRHREGR LSGVLNGVDE
260 270 280 290 300
KIWSPETDLL LASRYTRDTL EDKAENKRQL QIAMGLKVDD KVPLFAVVSR
310 320 330 340 350
LTSQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEYPGQVG
360 370 380 390 400
VQIGYHEAFS HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG
410 420 430 440 450
LADTVSDCSL ENLADGVASG FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF
460 470
VQRQAMAMDF SWQVAAKSYR ELYYRLK
Length:477
Mass (Da):52,822
Last modified:March 29, 2005 - v1
Checksum:i177CF37F8C97CF42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58535.1.
BA000007 Genomic DNA. Translation: BAB37697.1.
PIRiB98163.
C86009.
RefSeqiNP_312301.1. NC_002695.1.
WP_001197646.1. NZ_LPWC02000002.1.

Genome annotation databases

EnsemblBacteriaiAAG58535; AAG58535; Z4791.
BAB37697; BAB37697; BAB37697.
GeneIDi915868.
KEGGiece:Z4791.
ecs:ECs4274.
PATRICi18358113. VBIEscCol44059_4223.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58535.1.
BA000007 Genomic DNA. Translation: BAB37697.1.
PIRiB98163.
C86009.
RefSeqiNP_312301.1. NC_002695.1.
WP_001197646.1. NZ_LPWC02000002.1.

3D structure databases

ProteinModelPortaliP0A6V0.
SMRiP0A6V0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi155864.Z4791.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG58535; AAG58535; Z4791.
BAB37697; BAB37697; BAB37697.
GeneIDi915868.
KEGGiece:Z4791.
ecs:ECs4274.
PATRICi18358113. VBIEscCol44059_4223.

Phylogenomic databases

eggNOGiENOG4105CXW. Bacteria.
COG0297. LUCA.
HOGENOMiHOG000294941.
KOiK00703.
OMAiLLNAMRC.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciECOO157:GLGA-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth. 1 hit.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLGA_ECO57
AccessioniPrimary (citable) accession number: P0A6V0
Secondary accession number(s): P08323
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: March 29, 2005
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.