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Protein

Glycogen synthase

Gene

glgA

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.By similarity

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseBy similarity

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciECOL199310:C4216-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase (EC:2.4.1.21)
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene namesi
Name:glgA
Ordered Locus Names:c4216
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Glycogen synthasePRO_0000188612Add
BLAST

Proteomic databases

PRIDEiP0A6U9.

Interactioni

Protein-protein interaction databases

STRINGi199310.c4216.

Structurei

3D structure databases

ProteinModelPortaliP0A6U9.
SMRiP0A6U9. Positions 1-477.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000294941.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A6U9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDARVL LPAFPDIRRG
60 70 80 90 100
VTDAQVVSRR DTFAGHITLL FGHYNGVGIY LIDAPHLYDR PGSPYHDTNL
110 120 130 140 150
FAYTDNVLRF ALLGWVGAEM ASGLDPFWRP DVVHAHDWHA GLAPAYLAAR
160 170 180 190 200
GRPAKSVFTV HNLAYQGMFY AHHMNDIQLP WSFFNIHGLE FNGQISFLKA
210 220 230 240 250
GLYYADHITA VSPTYAREIT EPQFAYGMEG LLQQRHREGR LSGVLNGVDE
260 270 280 290 300
KIWSPETDLL LASRYTRDTL EDKAENKRQL QIAMGLKVDD KVPLFAVVSR
310 320 330 340 350
LTSQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEYPGQVG
360 370 380 390 400
VQIGYHEAFS HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG
410 420 430 440 450
LADTVSDCSL ENLADGVASG FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF
460 470
VQRQAMAMDF SWQVAAKSYR ELYYRLK
Length:477
Mass (Da):52,822
Last modified:March 29, 2005 - v1
Checksum:i177CF37F8C97CF42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN82654.1.
RefSeqiNP_756080.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN82654; AAN82654; c4216.
GeneIDi1036951.
KEGGiecc:c4216.
PATRICi18286178. VBIEscCol75197_3965.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN82654.1.
RefSeqiNP_756080.1. NC_004431.1.

3D structure databases

ProteinModelPortaliP0A6U9.
SMRiP0A6U9. Positions 1-477.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi199310.c4216.

Proteomic databases

PRIDEiP0A6U9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN82654; AAN82654; c4216.
GeneIDi1036951.
KEGGiecc:c4216.
PATRICi18286178. VBIEscCol75197_3965.

Phylogenomic databases

HOGENOMiHOG000294941.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciECOL199310:C4216-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPEC.

Entry informationi

Entry nameiGLGA_ECOL6
AccessioniPrimary (citable) accession number: P0A6U9
Secondary accession number(s): P08323
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: March 29, 2005
Last modified: January 7, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.