Reviewed,
UniProtKB/Swiss-Prot P0A6T3 (GAL1_ECOLI)
Last modified
June 16, 2009.
Version 40.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Galactokinase EC=2.7.1.6 Alternative name(s): Galactose kinase | ||||||
| Gene names |
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| Organism | Escherichia coli (strain K12) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 83333 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 382 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate. HAMAP MF_00246 |
| Pathway | Carbohydrate metabolism; galactose metabolism. HAMAP MF_00246 |
| Subcellular location | Cytoplasm Potential. |
| Sequence similarities | Belongs to the GHMP kinase family. GalK subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Galactose metabolism |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | carbohydrate phosphorylation Inferred from electronic annotation. Source: InterPro galactose metabolic processInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP galactokinase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed Ref.5 | ||||||
| Chain | 2 – 382 | 381 | Galactokinase HAMAP MF_00246 | PRO_0000184607 | |||||
Regions | |||||||||
| Nucleotide binding | 122 – 132 | 11 | ATP Potential | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| X02306 Genomic DNA. Translation: CAA26172.1. U00096 Genomic DNA. Translation: AAC73844.1. AP009048 Genomic DNA. Translation: BAA35419.1. U13636 Genomic DNA. Translation: AAB17019.1. | |
| PIR | KIECGG. B23044. |
| RefSeq | AP_001388.1. NP_415278.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 945358. |
| GenomeReviews | Gene locus JW0740 in contig AP009048_GR. Gene locus b0757 in contig U00096_GR. |
| KEGG | ecj:JW0740. eco:b0757. |
Organism-specific databases | |
| EchoBASE | EB0358. |
| EcoGene | EG10363. galK. |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P0A6T3. |
| OMA | P0A6T3. YNDGFVM. |
Enzyme and pathway databases | |
| BioCyc | EcoCyc:GALACTOKIN-MON. MetaCyc:GALACTOKIN-MON. |
Family and domain databases | |
| HAMAP | MF_00246. [Tree] |
| InterPro | IPR000705. Galactokinase. IPR019741. Galactokinase_CS. IPR019539. GalKase_gal_bd. IPR006204. GHMP_kinase. IPR013750. GHMP_kinase_C. IPR006203. GHMP_knse_ATP_bd_CS. IPR006206. Mev_galkinase. IPR014721. Ribosomal_S5_D2-type_fold. [Graphical view] |
| Gene3D | G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. |
| Pfam | PF10509. GalKase_gal_bdg. 1 hit. PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000530. Galactokinase. 1 hit. |
| PRINTS | PR00473. GALCTOKINASE. PR00959. MEVGALKINASE. |
| TIGRFAMs | TIGR00131. gal_kin. 1 hit. |
| PROSITE | PS00106. GALACTOKINASE. 1 hit. PS00627. GHMP_KINASES_ATP. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GAL1_ECOLI | ||||||||
| Accession | Primary (citable) accession number: P0A6T3 Secondary accession number(s): P06976 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Escherichia coli Escherichia coli (strain K12): entries and cross-references to EcoGene |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


