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Protein

Flagellar L-ring protein

Gene

flgH

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciECOO157:FLGH-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar L-ring protein
Alternative name(s):
Basal body L-ring protein
Gene namesi
Name:flgH
Ordered Locus Names:Z1717, ECs1457
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000000944422 – 232Flagellar L-ring proteinAdd BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi22N-palmitoyl cysteineSequence analysis1
Lipidationi22S-diacylglycerol cysteineSequence analysis1

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Subunit structurei

The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.By similarity

Protein-protein interaction databases

STRINGi155864.Z1717.

Structurei

3D structure databases

ProteinModelPortaliP0A6S1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FlgH family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107W7W. Bacteria.
COG2063. LUCA.
HOGENOMiHOG000280165.
KOiK02393.
OMAiEGPLGNN.

Family and domain databases

HAMAPiMF_00415. FlgH. 1 hit.
InterProiIPR000527. Flag_Lring.
[Graphical view]
PfamiPF02107. FlgH. 1 hit.
[Graphical view]
PRINTSiPR01008. FLGLRINGFLGH.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A6S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKNAAHTYA ISSLLVLSLT GCAWIPSTPL VQGATSAQPV PGPTPVANGS
60 70 80 90 100
IFQSAQPINY GYQPLFEDRR PRNIGDTLTI VLQENVSASK SSSANASRDG
110 120 130 140 150
KTNFGFDTVP RYLQGLFGNA RADVEASGGN TFNGKGGANA SNTFSGTLTV
160 170 180 190 200
TVDQVLVNGN LHVVGEKQIA INQGTEFIRF SGVVNPRTIS GSNTVPSTQV
210 220 230
ADARIEYVGN GYINEAQNMG WLQRFFLNLS PM
Length:232
Mass (Da):24,615
Last modified:March 29, 2005 - v1
Checksum:i862560170E6F63B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG55825.1.
BA000007 Genomic DNA. Translation: BAB34880.1.
PIRiA99811.
E85670.
RefSeqiNP_309484.1. NC_002695.1.
WP_001295442.1. NZ_LPWC02000004.1.

Genome annotation databases

EnsemblBacteriaiAAG55825; AAG55825; Z1717.
BAB34880; BAB34880; BAB34880.
GeneIDi912879.
KEGGiece:Z1717.
ecs:ECs1457.
PATRICi18352153. VBIEscCol44059_1303.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG55825.1.
BA000007 Genomic DNA. Translation: BAB34880.1.
PIRiA99811.
E85670.
RefSeqiNP_309484.1. NC_002695.1.
WP_001295442.1. NZ_LPWC02000004.1.

3D structure databases

ProteinModelPortaliP0A6S1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi155864.Z1717.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG55825; AAG55825; Z1717.
BAB34880; BAB34880; BAB34880.
GeneIDi912879.
KEGGiece:Z1717.
ecs:ECs1457.
PATRICi18352153. VBIEscCol44059_1303.

Phylogenomic databases

eggNOGiENOG4107W7W. Bacteria.
COG2063. LUCA.
HOGENOMiHOG000280165.
KOiK02393.
OMAiEGPLGNN.

Enzyme and pathway databases

BioCyciECOO157:FLGH-MONOMER.

Family and domain databases

HAMAPiMF_00415. FlgH. 1 hit.
InterProiIPR000527. Flag_Lring.
[Graphical view]
PfamiPF02107. FlgH. 1 hit.
[Graphical view]
PRINTSiPR01008. FLGLRINGFLGH.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFLGH_ECO57
AccessioniPrimary (citable) accession number: P0A6S1
Secondary accession number(s): P75940, Q9R7P0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.