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Protein

Flagellar L-ring protein

Gene

flgH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.By similarity

GO - Molecular functioni

GO - Biological processi

  • bacterial-type flagellum-dependent cell motility Source: InterPro
  • response to osmotic stress Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:FLGH-FLAGELLAR-L-RING

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar L-ring protein
Alternative name(s):
Basal body L-ring protein
Gene namesi
Name:flgH
Synonyms:fla FVIII, flaY
Ordered Locus Names:b1079, JW5153
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG20264 flgH

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Bacterial flagellum, Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000000944322 – 232Flagellar L-ring proteinAdd BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi22N-palmitoyl cysteineSequence analysis1
Lipidationi22S-diacylglycerol cysteineSequence analysis1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

EPDiP0A6S0
PaxDbiP0A6S0
PRIDEiP0A6S0

Interactioni

Subunit structurei

The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.By similarity

Protein-protein interaction databases

BioGridi4261033, 6 interactors
IntActiP0A6S0, 13 interactors
STRINGi316385.ECDH10B_1150

Structurei

3D structure databases

ProteinModelPortaliP0A6S0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FlgH family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107W7W Bacteria
COG2063 LUCA
HOGENOMiHOG000280165
InParanoidiP0A6S0
KOiK02393
OMAiSTRVANA
PhylomeDBiP0A6S0

Family and domain databases

HAMAPiMF_00415 FlgH, 1 hit
InterProiView protein in InterPro
IPR000527 Flag_Lring
PANTHERiPTHR34933 PTHR34933, 1 hit
PfamiView protein in Pfam
PF02107 FlgH, 1 hit
PRINTSiPR01008 FLGLRINGFLGH
PROSITEiView protein in PROSITE
PS51257 PROKAR_LIPOPROTEIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A6S0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKNAAHTYA ISSLLVLSLT GCAWIPSTPL VQGATSAQPV PGPTPVANGS
60 70 80 90 100
IFQSAQPINY GYQPLFEDRR PRNIGDTLTI VLQENVSASK SSSANASRDG
110 120 130 140 150
KTNFGFDTVP RYLQGLFGNA RADVEASGGN TFNGKGGANA SNTFSGTLTV
160 170 180 190 200
TVDQVLVNGN LHVVGEKQIA INQGTEFIRF SGVVNPRTIS GSNTVPSTQV
210 220 230
ADARIEYVGN GYINEAQNMG WLQRFFLNLS PM
Length:232
Mass (Da):24,615
Last modified:March 29, 2005 - v1
Checksum:i862560170E6F63B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74163.1
AP009048 Genomic DNA Translation: BAA35888.2
PIRiD64851
RefSeqiNP_415597.1, NC_000913.3
WP_001295442.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74163; AAC74163; b1079
BAA35888; BAA35888; BAA35888
GeneIDi946996
KEGGiecj:JW5153
eco:b1079
PATRICifig|1411691.4.peg.1189

Similar proteinsi

Entry informationi

Entry nameiFLGH_ECOLI
AccessioniPrimary (citable) accession number: P0A6S0
Secondary accession number(s): P75940, Q9R7P0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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