Reviewed, UniProtKB/Swiss-Prot P0A6G1 (CH10_ECO57)

Names and origin

Protein names

Recommended name:
    10 kDa chaperonin
Alternative name(s):
    Protein Cpn10
    groES protein

Gene names

Name:	groS
Synonyms:	groES, mopB
Ordered Locus Names:	Z5747, ECs5123

Organism

Escherichia coli O157:H7 [Complete proteome] [HAMAP]

Taxonomic identifier

83334 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	97 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. HAMAP MF_00580
Subunit structure	Heptamer of 7 subunits arranged in a ring. HAMAP MF_00580
Subcellular location	Cytoplasm HAMAP MF_00580.
Sequence similarities	Belongs to the groES chaperonin family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 97	97	10 kDa chaperonin HAMAP MF_00580		PRO_0000174748

Sequences

	Sequence		Length	Mass (Da)
	P0A6G1-1 [UniParc]. Last modified March 29, 2005. Version 1. Checksum: 76829E09B11217EF	FASTA	97	10,387
	10 20 30 40 50 60 MNIRPLHDRV IVKRKEVETK SAGGIVLTGS AAAKSTRGEV LAVGNGRILE NGEVKPLDVK 70 80 90 VGDIVIFNDG YGVKSEKIDN EEVLIMSESD ILAIVEA

References

[1]	"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R. Nature 409:529-533(2001) [PubMed: 11206551] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
[2]	"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. , Kuhara S., Shiba T., Hattori M., Shinagawa H. DNA Res. 8:11-22(2001) [PubMed: 11258796] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005174 Genomic DNA. Translation: AAG59341.1. BA000007 Genomic DNA. Translation: BAB38546.1.
PIR	A86110. C91269.
RefSeq	NP_290775.1. NP_313150.1.
3D structure databases
DisProt	DP00412.
ModBase	Search...
Genome annotation databases
GeneID	913836. 959981.
GenomeReviews	Gene locus Z5747 in contig AE005174_GR. Gene locus ECs5123 in contig BA000007_GR.
KEGG	ece:Z5747. ecs:ECs5123.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG703377.
OMA	SEKIDGE.
Enzyme and pathway databases
BioCyc	ECOL83334:ECS5123-MONOMER.
Family and domain databases
HAMAP	MF_00580. CH10. [Tree]
InterPro	IPR020818. Chaperonin_Cpn10. IPR018369. Chaprnonin_Cpn10_CS. IPR001476. Chaprnonin_Cpn10_subgroup. IPR011032. GroES-like. [Graphical view]
Gene3D	G3DSA:2.30.33.40. Chaprnin_Cpn10. 1 hit.
PANTHER	PTHR10772. Chaprnin_Cpn10. 1 hit.
Pfam	PF00166. Cpn10. 1 hit. [Graphical view]
PRINTS	PR00297. CHAPERONIN10.
SMART	SM00883. Cpn10. 1 hit. [Graphical view]
PROSITE	PS00681. CHAPERONINS_CPN10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CH10_ECO57

Accession

Primary (citable) accession number: P0A6G1
Secondary accession number(s): P05380

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2005
Last sequence update:	March 29, 2005
Last modified:	January 19, 2010
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)