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Protein

Iron-dependent repressor IdeR

Gene

ideR

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation
LigandIron

Enzyme and pathway databases

BioCyciMBOV233413:G1GT4-2820-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Iron-dependent repressor IdeR
Gene namesi
Name:ideR
Synonyms:dtxR
Ordered Locus Names:BQ2027_MB2730
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001419 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002011091 – 230Iron-dependent repressor IdeRAdd BLAST230

Interactioni

Subunit structurei

Homodimer.By similarity

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliP0A673
SMRiP0A673
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 65HTH dtxR-typePROSITE-ProRule annotationAdd BLAST62

Phylogenomic databases

HOGENOMiHOG000096101
OMAiDAQLMYT

Family and domain databases

Gene3Di1.10.10.10, 1 hit
1.10.60.10, 1 hit
2.30.30.90, 1 hit
InterProiView protein in InterPro
IPR007167 Fe-transptr_FeoA
IPR001367 Fe_dep_repressor
IPR036421 Fe_dep_repressor_sf
IPR038157 FeoA_core_dom
IPR022687 HTH_DTXR
IPR022689 Iron_dep_repressor
IPR008988 Transcriptional_repressor_C
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF02742 Fe_dep_repr_C, 1 hit
PF01325 Fe_dep_repress, 1 hit
PF04023 FeoA, 1 hit
SMARTiView protein in SMART
SM00899 FeoA, 1 hit
SM00529 HTH_DTXR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47979 SSF47979, 1 hit
SSF50037 SSF50037, 1 hit
PROSITEiView protein in PROSITE
PS50944 HTH_DTXR, 1 hit

Sequencei

Sequence statusi: Complete.

P0A673-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNELVDTTEM YLRTIYDLEE EGVTPLRARI AERLDQSGPT VSQTVSRMER
60 70 80 90 100
DGLLRVAGDR HLELTEKGRA LAIAVMRKHR LAERLLVDVI GLPWEEVHAE
110 120 130 140 150
ACRWEHVMSE DVERRLVKVL NNPTTSPFGN PIPGLVELGV GPEPGADDAN
160 170 180 190 200
LVRLTELPAG SPVAVVVRQL TEHVQGDIDL ITRLKDAGVV PNARVTVETT
210 220 230
PGGGVTIVIP GHENVTLPHE MAHAVKVEKV
Length:230
Mass (Da):25,233
Last modified:March 15, 2005 - v1
Checksum:i77B9CA98E04BDC27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LT708304 Genomic DNA Translation: SIU01348.1
RefSeqiNP_856376.1, NC_002945.3
WP_003413962.1, NC_002945.4

Genome annotation databases

EnsemblBacteriaiCDO43994; CDO43994; Mb2730
PATRICifig|233413.5.peg.2992

Similar proteinsi

Entry informationi

Entry nameiIDER_MYCBO
AccessioniPrimary (citable) accession number: P0A673
Secondary accession number(s): A0A1R3Y2D9
, O08190, Q50495, X2BLC3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: April 25, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health