P0A654 (Y3716_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0133 protein Rv3716c/MT3819

Gene names

Ordered Locus Names:	Rv3716c, MT3819
ORF Names:	MTV025.064c

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Homodimer By similarity. HAMAP MF_00274
Sequence similarities	Belongs to the UPF0133 family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	plasma membrane Inferred from direct assay. Source: MTBBASE
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	UPF0133 protein Rv3716c/MT3819 HAMAP MF_00274		PRO_0000170412

Sequences

	Sequence		Length	Mass (Da)
	P0A654 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 9D689EE3170AE782	FASTA	133	13,357
	10 20 30 40 50 60 MQPGGDMSAL LAQAQQMQQK LLEAQQQLAN SEVHGQAGGG LVKVVVKGSG EVIGVTIDPK 70 80 90 100 110 120 VVDPDDIETL QDLIVGAMRD ASQQVTKMAQ ERLGALAGAM RPPAPPAAPP GAPGMPGMPG 130 MPGAPGAPPV PGI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
[3]	"Identification of acidic, low molecular mass proteins of Mycobacterium tuberculosis strain H37Rv by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry." Mattow J., Jungblut P.R., Mueller E.-C., Kaufmann S.H.E. Proteomics 1:494-507(2001) [PubMed: 11681203] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY. Strain: ATCC 25618 / H37Rv.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842583 Genomic DNA. Translation: CAA18038.1. AE000516 Genomic DNA. Translation: AAK48188.1.
PIR	E70795.
RefSeq	NP_218233.1. NC_000962.2. NP_338374.1. NC_002755.2.
3D structure databases
ProteinModelPortal	P0A654.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000003786; EBMYCP00000003786; EBMYCG00000003784. EBMYCT00000070618; EBMYCP00000068677; EBMYCG00000070613.
GeneID	885595. 922679.
GenomeReviews	Gene locus MT3819 in contig AE000516_GR. Gene locus Rv3716c in contig AL123456_GR.
KEGG	mtc:MT3819. mtu:Rv3716c.
PATRIC	18130158. VBIMycTub22151_4171.
TIGR	MT3819.
Organism-specific databases
TubercuList	Rv3716c.
Phylogenomic databases
GeneTree	EBGT00050000015096.
HOGENOM	HBG734215.
OMA	MADFLGM.
PhylomeDB	P0A654.
ProtClustDB	PRK00153.
Family and domain databases
HAMAP	MF_00274. UPF0133. [Tree]
InterPro	IPR004401. UPF0133. [Graphical view]
Gene3D	G3DSA:3.30.1310.10. CHP103. 1 hit.
KO	K09747.
Pfam	PF02575. DUF149. 1 hit. [Graphical view]
PIRSF	PIRSF004555. UCP004555. 1 hit.
SUPFAM	SSF82607. CHP00103. 1 hit.
TIGRFAMs	TIGR00103. DNA_YbaB_EbfC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y3716_MYCTU

Accession

Primary (citable) accession number: P0A654
Secondary accession number(s): O69683

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program