Skip Header

Contribute Send feedback
Read comments (?) or add your own

P0A642 (Y2565_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized NTE family protein Rv2565/MT2641
Gene names
Ordered Locus Names:Rv2565, MT2641
ORF Names:MTCY9C4.03c
OrganismMycobacterium tuberculosis
Taxonomic identifier1773 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length583 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the NTE family.

Contains 1 cyclic nucleotide-binding domain.

Contains 1 patatin domain.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphosphatidylcholine metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytosol

Inferred from direct assay. Source: MTBBASE

   Molecular functionlysophospholipase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 583583Uncharacterized NTE family protein Rv2565/MT2641
PRO_0000172536

Regions

Domain309 – 469161Patatin
Nucleotide binding24 – 140117cNMP

Experimental info

Sequence conflict3751G → D in AAK46954. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P0A642 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: EC6EE062BAEC62F7

FASTA58362,124
        10         20         30         40         50         60 
MTTARRRPKR RGTDARTALR NVPILADIDD EQLERLATTV ERRHVPANQW LFHAGEPADS 

        70         80         90        100        110        120 
IYIVDSGRFV AVAPEGHVFA EMASGDSIGD LGVIAGAARS AGVRALRDGV VWRIAAETFT 

       130        140        150        160        170        180 
DMLEATPLLQ SAMLRAMARM LRQSRPAKTA RRPRVIGVVS NGDTAAAPMV DAIATSLDSH 

       190        200        210        220        230        240 
GRTAVIAPPV ETTSAVQEYD ELVEAFSETL DRAERSNDWV LVVADRGAGD LWRHYVSAQS 

       250        260        270        280        290        300 
DRLVVLVDQR YPPDAVDSLA TQRPVHLITC LAEPDPSWWD RLAPVSHHPA NSDGFGALAR 

       310        320        330        340        350        360 
RIAGRSLGLV MAGGGARGLA HFGVYQELTE AGVVIDRFGG TSSGAIASAA FALGMDAGDA 

       370        380        390        400        410        420 
IAAAREFIAG SDPLGDYTIP ISALTRGGRV DRLVQGFFGN TLIEHLPRGF FSVSADMITG 

       430        440        450        460        470        480 
DQIIHRRGSV SGAVRASISI PGLIPPVHNG EQLLVDGGLL NNLPANVMCA DTDGEVICVD 

       490        500        510        520        530        540 
LRRTFVPSKG FGLLPPIVTP PGLLRRLLTG TDNALPPLQE TLLRAFDLAA STANLRELPR 

       550        560        570        580 
VAAIIEPDVS KIGVLNFKQI DAALEAGRMA ARAALQAQPD LVR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX842580 Genomic DNA. Translation: CAB01050.1.
AE000516 Genomic DNA. Translation: AAK46954.1.
PIRA70729.
RefSeqNP_217081.1. NC_000962.2.
NP_337140.1. NC_002755.2.

3D structure databases

ProteinModelPortalP0A642.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000003448; EBMYCP00000003448; EBMYCG00000003446.
EBMYCT00000071878; EBMYCP00000069937; EBMYCG00000071873.
GeneID887288.
925673.
GenomeReviewsGene locus MT2641 in contig AE000516_GR.
Gene locus Rv2565 in contig AL123456_GR.
KEGGmtc:MT2641.
mtu:Rv2565.
PATRIC18127556. VBIMycTub22151_2881.
TIGRMT2641.

Organism-specific databases

TubercuListRv2565.

Phylogenomic databases

GeneTreeEBGT00050000014781.
HOGENOMHBG131045.
OMAWPEGADE.
PhylomeDBP0A642.
ProtClustDBCLSK791926.

Family and domain databases

InterProIPR016035. Acyl_Trfase/lysoPLipase.
IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR001423. LysoPLipase_patatin_CS.
IPR002641. Patatin/PLipase_A2-rel.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
Gene3DG3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit.
KOK07001.
PfamPF00027. cNMP_binding. 1 hit.
PF01734. Patatin. 1 hit.
[Graphical view]
SMARTSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMSSF52151. Acyl_Trfase/lysoPlipase. 1 hit.
SSF51206. cNMP_binding. 1 hit.
PROSITEPS00888. CNMP_BINDING_1. False negative.
PS00889. CNMP_BINDING_2. False negative.
PS50042. CNMP_BINDING_3. 1 hit.
PS01237. UPF0028. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY2565_MYCTU
AccessionPrimary (citable) accession number: P0A642
Secondary accession number(s): Q50733
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents