Reviewed, UniProtKB/Swiss-Prot P0A640 (Y1003_MYCTU)

Names and origin

Protein names

Recommended name:
    UPF0011 protein Rv1003/MT1032

Gene names

Ordered Locus Names:	Rv1003, MT1032
ORF Names:	MTCI237.19

Organism

Mycobacterium tuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0011 family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 285	285	UPF0011 protein Rv1003/MT1032		PRO_0000211946
Experimental info
	Sequence conflict	125	1	M → I in AAK45282. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P0A640-1 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 2F799A8057F64634	FASTA	285	29,665
	10 20 30 40 50 60 MSSGRLLLGA TPLGQPSDAS PRLAAALATA DVVAAEDTRR VRKLAKALDI RIGGRVVSLF 70 80 90 100 110 120 DRVEALRVTA LLDAINNGAT VLVVSDAGTP VISDPGYRLV AACIDAGVSV TCLPGPSAVT 130 140 150 160 170 180 TALVMSGLPA EKFCFEGFAP RKGAARRAWL AELAEERRTC VFFESPRRLA ACLNDAVEQL 190 200 210 220 230 240 GGARPAAICR ELTKVHEEVV RGSLDELAIW AAGGVLGEIT VVVAGAAPHA ELSSLIAQVE 250 260 270 280 EFVAAGIRVK DACSEVAAAH PGVRTRQLYD AVLQSRRETG GPAQP

References

[1]

"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.

[2]

"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX842575 Genomic DNA. Translation: CAB08145.1. AE000516 Genomic DNA. Translation: AAK45282.1.
PIR	F70602.
RefSeq	NP_215519.1. NP_335468.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	887935. 925167.
GenomeReviews	Gene locus MT1032 in contig AE000516_GR. Gene locus Rv1003 in contig AL123456_GR.
KEGG	mtc:MT1032. mtu:Rv1003.
TIGR	MT1032.
Organism-specific databases
TubercuList	Rv1003.
Phylogenomic databases
HOGENOM	HBG529058.
OMA	ASDRFCF.
Family and domain databases
InterPro	IPR000878. 4pyrrol_Mease. IPR008189. UPF0011. IPR018063. UPF0011_CS. [Graphical view]
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PROSITE	PS01296. UPF0011. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y1003_MYCTU

Accession

Primary (citable) accession number: P0A640
Secondary accession number(s): O05588

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	December 15, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)