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P0A517

- CP124_MYCBO

UniProt

P0A517 - CP124_MYCBO

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Protein

Putative cytochrome P450 124

Gene

cyp124

Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Cofactori

hemeBy similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi379 – 3791Iron (heme axial ligand)By similarity

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. monooxygenase activity Source: UniProtKB-KW
  4. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative cytochrome P450 124 (EC:1.14.-.-)
Gene namesi
Name:cyp124
Ordered Locus Names:Mb2289
OrganismiMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Taxonomic identifieri233413 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001419: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 428428Putative cytochrome P450 124PRO_0000052277Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi233413.Mb2289.

Structurei

3D structure databases

ProteinModelPortaliP0A517.
SMRiP0A517. Positions 3-428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Phylogenomic databases

eggNOGiCOG2124.
HOGENOMiHOG000243680.
KOiK00517.
OMAiIHATEEP.
OrthoDBiEOG6QVRCK.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
[Graphical view]
PfamiPF00067. p450. 2 hits.
[Graphical view]
PRINTSiPR00359. BP450.
SUPFAMiSSF48264. SSF48264. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A517-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLNTAIATR VNGTPPPEVP IADIELGSLD FWALDDDVRD GAFATLRREA
60 70 80 90 100
PISFWPTIEL PGFVAGNGHW ALTKYDDVFY ASRHPDIFSS YPNITINDQT
110 120 130 140 150
PELAEYFGSM IVLDDPRHQR LRSIVSRAFT PKVVARIEAA VRDRAHRLVS
160 170 180 190 200
SMIANNPDRQ ADLVSELAGP LPLQIICDMM GIPKADHQRI FHWTNVILGF
210 220 230 240 250
GDPDLATDFD EFMQVSADIG AYATALAEDR RVNHHDDLTS SLVEAEVDGE
260 270 280 290 300
RLSSREIASF FILLVVAGNE TTRNAITHGV LALSRYPEQR DRWWSDFDGL
310 320 330 340 350
APTAVEEIVR WASPVVYMRR TLTQDIELRG TKMAAGDKVS LWYCSANRDE
360 370 380 390 400
SKFADPWTFD LARNPNPHLG FGGGGAHFCL GANLARREIR VAFDELRRQM
410 420
PDVVATEEPA RLLSQFIHGI KTLPVTWS
Length:428
Mass (Da):47,825
Last modified:March 15, 2005 - v1
Checksum:i76B1F3C5AE348591
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO43546.1.
RefSeqiNP_855938.1. NC_002945.3.

Genome annotation databases

EnsemblBacteriaiCAD97150; CAD97150; Mb2289.
GeneIDi1090370.
KEGGimbo:Mb2289.
PATRICi18006738. VBIMycBov88188_2514.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248333 Genomic DNA. Translation: CDO43546.1 .
RefSeqi NP_855938.1. NC_002945.3.

3D structure databases

ProteinModelPortali P0A517.
SMRi P0A517. Positions 3-428.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 233413.Mb2289.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD97150 ; CAD97150 ; Mb2289 .
GeneIDi 1090370.
KEGGi mbo:Mb2289.
PATRICi 18006738. VBIMycBov88188_2514.

Phylogenomic databases

eggNOGi COG2124.
HOGENOMi HOG000243680.
KOi K00517.
OMAi IHATEEP.
OrthoDBi EOG6QVRCK.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
[Graphical view ]
Pfami PF00067. p450. 2 hits.
[Graphical view ]
PRINTSi PR00359. BP450.
SUPFAMi SSF48264. SSF48264. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-935 / AF2122/97.

Entry informationi

Entry nameiCP124_MYCBO
AccessioniPrimary (citable) accession number: P0A517
Secondary accession number(s): Q50696, X2BKK6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: November 26, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3