Putative cytochrome P450 124 - Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

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P0A517 (CP124_MYCBO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 50. History...

Clusters with 100%, 90%, 50% identity |

Documents (1) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Putative cytochrome P450 124
EC=1.14.-.-

Gene names

Name:	cyp124
Ordered Locus Names:	Mb2289

Organism

Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) [Complete proteome] [HAMAP]

Taxonomic identifier

233413 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex ›

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Heme group By similarity.
Sequence similarities	Belongs to the cytochrome P450 family.

Ontologies

Keywords
Ligand	Heme Iron Metal-binding
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro monooxygenase activity Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 428

428

Putative cytochrome P450 124

PRO_0000052277

Sites

Metal binding

379

Iron (heme axial ligand) By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

P0A517 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 76B1F3C5AE348591
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FASTA

428

47,825

        10         20         30         40         50         60 
MGLNTAIATR VNGTPPPEVP IADIELGSLD FWALDDDVRD GAFATLRREA PISFWPTIEL 

        70         80         90        100        110        120 
PGFVAGNGHW ALTKYDDVFY ASRHPDIFSS YPNITINDQT PELAEYFGSM IVLDDPRHQR 

       130        140        150        160        170        180 
LRSIVSRAFT PKVVARIEAA VRDRAHRLVS SMIANNPDRQ ADLVSELAGP LPLQIICDMM 

       190        200        210        220        230        240 
GIPKADHQRI FHWTNVILGF GDPDLATDFD EFMQVSADIG AYATALAEDR RVNHHDDLTS 

       250        260        270        280        290        300 
SLVEAEVDGE RLSSREIASF FILLVVAGNE TTRNAITHGV LALSRYPEQR DRWWSDFDGL 

       310        320        330        340        350        360 
APTAVEEIVR WASPVVYMRR TLTQDIELRG TKMAAGDKVS LWYCSANRDE SKFADPWTFD 

       370        380        390        400        410        420 
LARNPNPHLG FGGGGAHFCL GANLARREIR VAFDELRRQM PDVVATEEPA RLLSQFIHGI 


KTLPVTWS

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References

[1]

"The complete genome sequence of Mycobacterium bovis."
Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M., Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B., Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.

Hewinson R.G.
Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-935 / AF2122/97.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248342 Genomic DNA. Translation: CAD97150.1.
RefSeq	NP_855938.1. NC_002945.3.
3D structure databases
ProteinModelPortal	P0A517.
SMR	P0A517. Positions 3-428.
ModBase	Search...
Protein-protein interaction databases
STRING	233413.Mb2289.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD97150; CAD97150; Mb2289.
GeneID	1090370.
KEGG	mbo:Mb2289.
PATRIC	18006738. VBIMycBov88188_2514.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2124.
HOGENOM	HOG000243680.
KO	K00517.
OMA	HWALTRH.
ProtClustDB	CLSK791735.
Family and domain databases
Gene3D	1.10.630.10. 1 hit.
InterPro	IPR001128. Cyt_P450. IPR002397. Cyt_P450_B. [Graphical view]
Pfam	PF00067. p450. 2 hits. [Graphical view]
PRINTS	PR00359. BP450.
SUPFAM	SSF48264. Cytochrome_P450. 1 hit.
PROSITE	PS00086. CYTOCHROME_P450. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CP124_MYCBO

Accession

Primary (citable) accession number: P0A517
Secondary accession number(s): Q50696

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry information

Relevant documents