Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P0A4S7

- LFTR_BRUME

UniProt

P0A4S7 - LFTR_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:BMEI1064
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000207208Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEI1064.

Structurei

3D structure databases

ProteinModelPortaliP0A4S7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000102326.
KOiK00684.
OMAiIGHAHSV.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A4S7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAEAPPDDD IIEPEMLLRA YATGIFPMAE EADDPEVFWV RPEKRGVIPL
60 70 80 90 100
DGFHIPRSLQ KTIRQGIFEI RLDSNFAGVI EGCASGTGER ARTWINEPIR
110 120 130 140 150
RAYAKLFEIG HCHTVEAWYE GKLAGGLYGV TLGRAFFGES MFTRKRDASK
160 170 180 190 200
VCLAYLVQHL SRQGFVLLDT QFTTPHLERF GALEVPRKEY EEMLERALEG

IARF
Length:204
Mass (Da):23,153
Last modified:March 15, 2005 - v1
Checksum:i2B2155002265E0EC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL52245.1.
PIRiAB3385.
RefSeqiNP_539981.1. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL52245; AAL52245; BMEI1064.
GeneIDi1196775.
KEGGibme:BMEI1064.
PATRICi17797912. VBIBruMel146950_0771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL52245.1 .
PIRi AB3385.
RefSeqi NP_539981.1. NC_003317.1.

3D structure databases

ProteinModelPortali P0A4S7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI1064.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL52245 ; AAL52245 ; BMEI1064 .
GeneIDi 1196775.
KEGGi bme:BMEI1064.
PATRICi 17797912. VBIBruMel146950_0771.

Phylogenomic databases

HOGENOMi HOG000102326.
KOi K00684.
OMAi IGHAHSV.
OrthoDBi EOG6WX4R3.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiLFTR_BRUME
AccessioniPrimary (citable) accession number: P0A4S7
Secondary accession number(s): Q8G123, Q8YGU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3