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P0A4J1 (SODM_LACLA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Mn]
EC=1.15.1.1
Gene names
Name:sodA
Ordered Locus Names:LL0408
ORF Names:L12227
OrganismLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) [Reference proteome] [HAMAP]
Taxonomic identifier272623 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Lactococcus ›

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 manganese ion per subunit By similarity.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
   LigandManganese
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processsuperoxide metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Superoxide dismutase [Mn]
PRO_0000160040

Sites

Metal binding271Manganese By similarity
Metal binding821Manganese By similarity
Metal binding1681Manganese By similarity
Metal binding1721Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
P0A4J1 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 2865BB33801DB644

FASTA20623,254
        10         20         30         40         50         60 
MAFTLPELPY APNALEPFFD EATMRLHHGK HHQTYVNNLN AAIEKHNELD DLSLEELLTD 

        70         80         90        100        110        120 
LSAIPEDIRT AVRNNGGGHL NHSQFWLWLR PNTDGSENHA DGEIGDAIAK EFGSFETFKT 

       130        140        150        160        170        180 
EFKAAATGRF GSGWAWLVVD EAGKLKVVST ANQDNPISEG LTPVLGLDVW EHAYYLKYHN 

       190        200 
VRPDYIEAFF NLVNWDKVNE LYAKAK

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IL1403.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005176 Genomic DNA. Translation: AAK04506.1.
PIRH86675.
RefSeqNP_266564.1. NC_002662.1.

3D structure databases

ProteinModelPortalP0A4J1.
SMRP0A4J1. Positions 2-204.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272623.L12227.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK04506; AAK04506; L12227.
GeneID1114019.
KEGGlla:L12227.
PATRIC22293022. VBILacLac136773_0442.

Phylogenomic databases

eggNOGCOG0605.
HOGENOMHOG000013583.
KOK04564.
OMADYISAFW.
OrthoDBEOG63NMNT.
ProtClustDBCLSK697212.

Enzyme and pathway databases

BioCycLLAC272623:GHSH-436-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODM_LACLA
AccessionPrimary (citable) accession number: P0A4J1
Secondary accession number(s): P50911
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: November 13, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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