sodA

Functionⁱ

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityⁱ

2 superoxide + 2 H⁺ = O₂ + H₂O₂.

Cofactorⁱ

Mn²⁺By similarityNote: Binds 1 Mn²⁺ ion per subunit.By similarity

Sites

Feature key	Position(s)	Length	Description
Metal bindingⁱ	27 – 27	1	ManganeseBy similarity
Metal bindingⁱ	82 – 82	1	ManganeseBy similarity
Metal bindingⁱ	168 – 168	1	ManganeseBy similarity
Metal bindingⁱ	172 – 172	1	ManganeseBy similarity

Enzyme and pathway databases

BioCycⁱ	LLAC272623:GHSH-436-MONOMER.

BioCycⁱ

LLAC272623:GHSH-436-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Superoxide dismutase [Mn] (EC:1.15.1.1)
Gene namesⁱ	Name:sodA Ordered Locus Names:LL0408 ORF Names:L12227
Organismⁱ	Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Taxonomic identifierⁱ	272623 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Lactococcus › Lactococcus lactis › Lactococcus lactis subsp. lactis
Proteomesⁱ	UP000002196 Componentⁱ: Chromosome

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Chainⁱ	1 – 206	206	Superoxide dismutase [Mn]		PRO_0000160040	Add BLAST

Proteomic databases

PaxDbⁱ	P0A4J1.

PaxDbⁱ

P0A4J1.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	272623.L12227.

STRINGⁱ

272623.L12227.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P0A4J1.
SMRⁱ	P0A4J1. Positions 2-204.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the iron/manganese superoxide dismutase family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG4105CK4. Bacteria. COG0605. LUCA.
HOGENOMⁱ	HOG000013583.
KOⁱ	K04564.
OMAⁱ	INQGGGH.

Family and domain databases

InterProⁱ	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHERⁱ	PTHR11404. PTHR11404. 1 hit.
Pfamⁱ	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSFⁱ	PIRSF000349. SODismutase. 1 hit.
PRINTSⁱ	PR01703. MNSODISMTASE.
SUPFAMⁱ	SSF46609. SSF46609. 1 hit. SSF54719. SSF54719. 1 hit.
PROSITEⁱ	PS00088. SOD_MN. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

P0A4J1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAFTLPELPY APNALEPFFD EATMRLHHGK HHQTYVNNLN AAIEKHNELD 
        60         70         80         90        100
DLSLEELLTD LSAIPEDIRT AVRNNGGGHL NHSQFWLWLR PNTDGSENHA 
       110        120        130        140        150
DGEIGDAIAK EFGSFETFKT EFKAAATGRF GSGWAWLVVD EAGKLKVVST 
       160        170        180        190        200
ANQDNPISEG LTPVLGLDVW EHAYYLKYHN VRPDYIEAFF NLVNWDKVNE 

LYAKAK

Length:206

Mass (Da):23,254

Last modified:March 15, 2005 - v1

Checksum:ⁱ2865BB33801DB644

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE005176 Genomic DNA. Translation: AAK04506.1.
PIRⁱ	H86675.
RefSeqⁱ	NP_266564.1. NC_002662.1. WP_003131560.1. NC_002662.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAK04506; AAK04506; L12227.
GeneIDⁱ	1114019.
KEGGⁱ	lla:L12227.
PATRICⁱ	22293022. VBILacLac136773_0442.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE005176 Genomic DNA. Translation: AAK04506.1.
PIRⁱ	H86675.
RefSeqⁱ	NP_266564.1. NC_002662.1. WP_003131560.1. NC_002662.1.

3D structure databases

ProteinModelPortalⁱ	P0A4J1.
SMRⁱ	P0A4J1. Positions 2-204.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	272623.L12227.

STRINGⁱ

272623.L12227.

Proteomic databases

PaxDbⁱ	P0A4J1.

PaxDbⁱ

P0A4J1.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAK04506; AAK04506; L12227.
GeneIDⁱ	1114019.
KEGGⁱ	lla:L12227.
PATRICⁱ	22293022. VBILacLac136773_0442.

Phylogenomic databases

eggNOGⁱ	ENOG4105CK4. Bacteria. COG0605. LUCA.
HOGENOMⁱ	HOG000013583.
KOⁱ	K04564.
OMAⁱ	INQGGGH.

Enzyme and pathway databases

BioCycⁱ	LLAC272623:GHSH-436-MONOMER.

BioCycⁱ

LLAC272623:GHSH-436-MONOMER.

Family and domain databases

InterProⁱ	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHERⁱ	PTHR11404. PTHR11404. 1 hit.
Pfamⁱ	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSFⁱ	PIRSF000349. SODismutase. 1 hit.
PRINTSⁱ	PR01703. MNSODISMTASE.
SUPFAMⁱ	SSF46609. SSF46609. 1 hit. SSF54719. SSF54719. 1 hit.
PROSITEⁱ	PS00088. SOD_MN. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

SODM_LACLA

Accessionⁱ

Primary (citable) accession number: P0A4J1
Secondary accession number(s): P50911

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P0A4J1 (SODM_LACLA)

UniProt

P0A4J1 - SODM_LACLA

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Superoxide dismutase [Mn]

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ