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P0A4J1

- SODM_LACLA

UniProt

P0A4J1 - SODM_LACLA

Protein

Superoxide dismutase [Mn]

Gene

sodA

Organism
Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (15 Mar 2005)
      Previous versions | rss
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    Functioni

    Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.

    Cofactori

    Binds 1 manganese ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi27 – 271ManganeseBy similarity
    Metal bindingi82 – 821ManganeseBy similarity
    Metal bindingi168 – 1681ManganeseBy similarity
    Metal bindingi172 – 1721ManganeseBy similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciLLAC272623:GHSH-436-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Mn] (EC:1.15.1.1)
    Gene namesi
    Name:sodA
    Ordered Locus Names:LL0408
    ORF Names:L12227
    OrganismiLactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
    Taxonomic identifieri272623 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
    ProteomesiUP000002196: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 206206Superoxide dismutase [Mn]PRO_0000160040Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272623.L12227.

    Structurei

    3D structure databases

    ProteinModelPortaliP0A4J1.
    SMRiP0A4J1. Positions 2-204.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0605.
    HOGENOMiHOG000013583.
    KOiK04564.
    OMAiTIFWQIM.
    OrthoDBiEOG63NMNT.

    Family and domain databases

    InterProiIPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view]
    PANTHERiPTHR11404. PTHR11404. 1 hit.
    PfamiPF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000349. SODismutase. 1 hit.
    PRINTSiPR01703. MNSODISMTASE.
    SUPFAMiSSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEiPS00088. SOD_MN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0A4J1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAFTLPELPY APNALEPFFD EATMRLHHGK HHQTYVNNLN AAIEKHNELD    50
    DLSLEELLTD LSAIPEDIRT AVRNNGGGHL NHSQFWLWLR PNTDGSENHA 100
    DGEIGDAIAK EFGSFETFKT EFKAAATGRF GSGWAWLVVD EAGKLKVVST 150
    ANQDNPISEG LTPVLGLDVW EHAYYLKYHN VRPDYIEAFF NLVNWDKVNE 200
    LYAKAK 206
    Length:206
    Mass (Da):23,254
    Last modified:March 15, 2005 - v1
    Checksum:i2865BB33801DB644
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005176 Genomic DNA. Translation: AAK04506.1.
    PIRiH86675.
    RefSeqiNP_266564.1. NC_002662.1.

    Genome annotation databases

    EnsemblBacteriaiAAK04506; AAK04506; L12227.
    GeneIDi1114019.
    KEGGilla:L12227.
    PATRICi22293022. VBILacLac136773_0442.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005176 Genomic DNA. Translation: AAK04506.1 .
    PIRi H86675.
    RefSeqi NP_266564.1. NC_002662.1.

    3D structure databases

    ProteinModelPortali P0A4J1.
    SMRi P0A4J1. Positions 2-204.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272623.L12227.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK04506 ; AAK04506 ; L12227 .
    GeneIDi 1114019.
    KEGGi lla:L12227.
    PATRICi 22293022. VBILacLac136773_0442.

    Phylogenomic databases

    eggNOGi COG0605.
    HOGENOMi HOG000013583.
    KOi K04564.
    OMAi TIFWQIM.
    OrthoDBi EOG63NMNT.

    Enzyme and pathway databases

    BioCyci LLAC272623:GHSH-436-MONOMER.

    Family and domain databases

    InterProi IPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view ]
    PANTHERi PTHR11404. PTHR11404. 1 hit.
    Pfami PF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000349. SODismutase. 1 hit.
    PRINTSi PR01703. MNSODISMTASE.
    SUPFAMi SSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEi PS00088. SOD_MN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403."
      Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.
      Genome Res. 11:731-753(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IL1403.

    Entry informationi

    Entry nameiSODM_LACLA
    AccessioniPrimary (citable) accession number: P0A4J1
    Secondary accession number(s): P50911
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2005
    Last sequence update: March 15, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3