Reviewed,
UniProtKB/Swiss-Prot P0A457 (T2A1_ANASP)
Last modified
June 16, 2009.
Version 22.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Type-2 restriction enzyme AvaI Short name=R.AvaI EC=3.1.21.4 Alternative name(s): Type II restriction enzyme AvaI Endonuclease AvaI | ||||
| Gene names |
| ||||
| Organism | Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 103690 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc |
Protein attributes
| Sequence length | 315 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Recognizes the double-stranded sequence CYCGRG and cleaves after C-1 By similarity. |
| Catalytic activity | Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Restriction system |
| Molecular function | Endonuclease Hydrolase Nuclease |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | DNA restriction-modification system Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro Type II site-specific deoxyribonuclease activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 315 | 315 | Type-2 restriction enzyme AvaI | PRO_0000077279 | |||
Sequences
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References
| [1] | "Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. Tabata S.DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| BA000019 Genomic DNA. Translation: BAB75330.1. | |
| PIR | AH2259. |
| RefSeq | NP_487671.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1DC1 based on UniProtKB P70985. |
| ModBase | Search... |
Protein family/group databases | |
| REBASE | 165. AvaI. |
Genome annotation databases | |
| GeneID | 1107229. |
| GenomeReviews | Gene locus all3631 in contig BA000019_GR. |
| KEGG | ana:all3631. |
| NMPDR | fig|103690.1.peg.3938. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P0A457. |
| OMA | P0A457. AGADEHW. |
Enzyme and pathway databases | |
| BioCyc | NSP103690:ALL3631-MON. |
Family and domain databases | |
| InterPro | IPR011544. Restrct_endonuc_II_Cfr10/BsoB1. IPR015277. Restrict_endonuc_II_AvaI/BsoBI. [Graphical view] |
| Gene3D | G3DSA:3.40.91.10. Restrct_endonuc_II_Cfr10/BsoB1. 1 hit. |
| Pfam | PF09194. Endonuc-BsobI. 1 hit. [Graphical view] |
| ProDom | PD040871. Restrict_endonuc_II_AvaI/BsoBI. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| ProtoNet | Search... |
Entry information
| Entry name | T2A1_ANASP | ||||||||
| Accession | Primary (citable) accession number: P0A457 Secondary accession number(s): P70803 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Restriction enzymes and methylases Classification of restriction enzymes and methylases and list of entries |

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