Galactitol-specific phosphotransferase enzyme IIB component - Escherichia coli O6

Contribute

Read comments (?) or add your own

P0A435 (PTKB_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

text xml rdf/xml gff fasta

to top of page

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

to top of page

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Galactitol-specific phosphotransferase enzyme IIB component
EC=2.7.1.69

Alternative name(s):
EIIB-Gat
PTS system galactitol-specific EIIB component

Gene names

Name:	gatB
Ordered Locus Names:	c2618

Organism

Escherichia coli O6 [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport By similarity.
Catalytic activity	Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.
Subcellular location	Cytoplasm By similarity.
Domain	The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain.
Sequence similarities	Contains 1 PTS EIIB type-2 domain.

Ontologies

Keywords
Biological process	Galactitol metabolism Phosphotransferase system Sugar transport Transport
Cellular component	Cytoplasm
Molecular function	Transferase
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	galactitol metabolic process Inferred from electronic annotation. Source: UniProtKB-KW phosphoenolpyruvate-dependent sugar phosphotransferase system Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Inferred from electronic annotation. Source: EC sugar:hydrogen symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

94

Galactitol-specific phosphotransferase enzyme IIB component

PRO_0000186573

Regions

Domain

94

PTS EIIB type-2

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

94

Helix Strand Turn

Sequences

Sequence

Length

Mass (Da)

Tools

P0A435 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 44D4988E0ACACCCF
Show »

94

10,195

        10         20         30         40         50         60 
MKRKIIVACG GAVATSTMAA EEIKELCQSH NIPVELIQCR VNEIETYMDG VHLICTTARV 

        70         80         90 
DRSFGDIPLV HGMPFVSGVG IEALQNKILT ILQG

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli."
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed: 12471157] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O6:H1 / CFT073 / ATCC 700928 / UPEC.

+

Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE014075 Genomic DNA. Translation: AAN81074.1.

RefSeq

NP_754506.1. NC_004431.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1TVM	NMR	-	A	2-94	[»]

ProteinModelPortal

SMR

P0A435. Positions 2-94.

ModBase

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

EBESCT00000043045; EBESCP00000041394; EBESCG00000042095.

GeneID

GenomeReviews

Gene locus c2618 in contig AE014075_GR.

KEGG

PATRIC

18283110. VBIEscCol75197_2463.

Organism-specific databases

CMR

Phylogenomic databases

GeneTree

EBGT00050000009313.

HOGENOM

OMA

ProtClustDB

Family and domain databases

InterPro

IPR013011. PTS_EIIB_2.
IPR003501. PTS_EIIB_2/3.
[Graphical view]

KO

Pfam

PF02302. PTS_IIB. 1 hit.
[Graphical view]

PROSITE

PS51099. PTS_EIIB_TYPE_2. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

PTKB_ECOL6

Accession

Primary (citable) accession number: P0A435
Secondary accession number(s): Q8X7H5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of page

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents