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Protein

Photosystem I P700 chlorophyll a apoprotein A1

Gene

psaA

Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.4 Publications

Catalytic activityi

Reduced plastocyanin + oxidized ferredoxin + light = oxidized plastocyanin + reduced ferredoxin.4 Publications

Cofactori

Note: PSI electron transfer chain: 5 chlorophyll a, 1 chlorophyll a', 2 phylloquinones and 3 4Fe-4S clusters. PSI core antenna: 90 chlorophyll a, 22 carotenoids, 3 phospholipids and 1 galactolipid. P700 is a chlorophyll a/chlorophyll a' dimer, A0 is one or more chlorophyll a, A1 is one or both phylloquinones and FX is a shared 4Fe-4S iron-sulfur center.4 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi578Iron-sulfur (4Fe-4S); shared with dimeric partner1 Publication1
Metal bindingi587Iron-sulfur (4Fe-4S); shared with dimeric partner1 Publication1
Metal bindingi680Magnesium (chlorophyll-a' A1 axial ligand; P700 special pair); via tele nitrogen1 Publication1
Metal bindingi688Magnesium (chlorophyll-a A3 axial ligand)1 Publication1
Binding sitei696Chlorophyll-a A32 Publications1
Binding sitei697Phylloquinone A2 Publications1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Photosynthesis, Transport
Ligand4Fe-4S, Chlorophyll, Chromophore, Iron, Iron-sulfur, Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Photosystem I P700 chlorophyll a apoprotein A1 (EC:1.97.1.124 Publications)
Alternative name(s):
PsaA
Gene namesi
Name:psaA
Ordered Locus Names:tlr0731
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeThermosynechococcus
Proteomesi
  • UP000000440 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 64CytoplasmicCuratedAdd BLAST64
Transmembranei65 – 96Helical; Name=IAdd BLAST32
Topological domaini97 – 155Lumenal, thylakoidCuratedAdd BLAST59
Transmembranei156 – 179Helical; Name=IIAdd BLAST24
Topological domaini180 – 192CytoplasmicCuratedAdd BLAST13
Transmembranei193 – 217Helical; Name=IIIAdd BLAST25
Topological domaini218 – 293Lumenal, thylakoidCuratedAdd BLAST76
Transmembranei294 – 311Helical; Name=IVAdd BLAST18
Topological domaini312 – 352CytoplasmicCuratedAdd BLAST41
Transmembranei353 – 376Helical; Name=VAdd BLAST24
Topological domaini377 – 386Lumenal, thylakoidCurated10
Transmembranei387 – 418Helical; Name=VIAdd BLAST32
Topological domaini419 – 436CytoplasmicCuratedAdd BLAST18
Transmembranei437 – 468Helical; Name=VIIAdd BLAST32
Topological domaini469 – 532Lumenal, thylakoidCuratedAdd BLAST64
Transmembranei533 – 558Helical; Name=VIIIAdd BLAST26
Topological domaini559 – 590CytoplasmicCuratedAdd BLAST32
Transmembranei591 – 619Helical; Name=IXAdd BLAST29
Topological domaini620 – 668Lumenal, thylakoidCuratedAdd BLAST49
Transmembranei669 – 690Helical; Name=XAdd BLAST22
Topological domaini691 – 723CytoplasmicCuratedAdd BLAST33
Transmembranei724 – 753Helical; Name=XIAdd BLAST30

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Photosystem I, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000885911 – 755Photosystem I P700 chlorophyll a apoprotein A1Add BLAST755

Interactioni

Subunit structurei

The PsaA/B heterodimer binds the P700 chlorophyll special pair and subsequent electron acceptors. PSI consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The cyanobacterial PSI reaction center is composed of one copy each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric complexes.4 Publications

Protein-protein interaction databases

STRINGi197221.tlr0731.

Structurei

Secondary structure

1755
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi16 – 19Combined sources4
Turni25 – 29Combined sources5
Turni31 – 34Combined sources4
Helixi36 – 38Combined sources3
Helixi46 – 53Combined sources8
Turni54 – 56Combined sources3
Helixi58 – 60Combined sources3
Helixi65 – 96Combined sources32
Helixi100 – 105Combined sources6
Turni107 – 109Combined sources3
Helixi123 – 126Combined sources4
Beta strandi127 – 131Combined sources5
Beta strandi134 – 138Combined sources5
Helixi143 – 149Combined sources7
Helixi155 – 181Combined sources27
Beta strandi183 – 185Combined sources3
Helixi187 – 190Combined sources4
Helixi193 – 202Combined sources10
Helixi204 – 218Combined sources15
Helixi220 – 227Combined sources8
Turni228 – 230Combined sources3
Helixi241 – 244Combined sources4
Helixi246 – 251Combined sources6
Turni267 – 270Combined sources4
Helixi272 – 275Combined sources4
Turni276 – 278Combined sources3
Turni287 – 289Combined sources3
Helixi294 – 311Combined sources18
Beta strandi318 – 320Combined sources3
Helixi325 – 331Combined sources7
Beta strandi335 – 337Combined sources3
Turni338 – 343Combined sources6
Helixi344 – 350Combined sources7
Helixi352 – 376Combined sources25
Helixi387 – 418Combined sources32
Helixi422 – 425Combined sources4
Beta strandi426 – 428Combined sources3
Helixi429 – 434Combined sources6
Helixi437 – 453Combined sources17
Helixi456 – 468Combined sources13
Helixi471 – 473Combined sources3
Beta strandi474 – 476Combined sources3
Helixi485 – 496Combined sources12
Turni499 – 501Combined sources3
Beta strandi513 – 515Combined sources3
Beta strandi518 – 520Combined sources3
Beta strandi523 – 526Combined sources4
Helixi533 – 558Combined sources26
Helixi569 – 572Combined sources4
Helixi591 – 620Combined sources30
Beta strandi623 – 625Combined sources3
Beta strandi631 – 633Combined sources3
Turni634 – 637Combined sources4
Helixi639 – 642Combined sources4
Helixi646 – 651Combined sources6
Helixi654 – 657Combined sources4
Helixi659 – 663Combined sources5
Helixi670 – 691Combined sources22
Helixi694 – 710Combined sources17
Beta strandi716 – 718Combined sources3
Helixi724 – 754Combined sources31

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C51X-ray4.0
1JB0X-ray2.50A1-755[»]
2PPSX-ray4.0
3PCQX-ray8.98A1-755[»]
4FE1X-ray4.92A1-755[»]
ProteinModelPortaliP0A405.
SMRiP0A405.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A405.

Family & Domainsi

Sequence similaritiesi

Belongs to the PsaA/PsaB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105MN0. Bacteria.
ENOG410XT0I. LUCA.
HOGENOMiHOG000276868.
KOiK02689.
OMAiMFLGAHF.
OrthoDBiPOG091H09L9.

Family and domain databases

Gene3Di1.20.1130.10. 1 hit.
HAMAPiMF_00458. PSI_PsaA. 1 hit.
InterProiView protein in InterPro
IPR006243. PSI_PsaA.
IPR001280. PSI_PsaA/B.
IPR020586. PSI_PsaA/B_CS.
PANTHERiPTHR30128:SF20. PTHR30128:SF20. 1 hit.
PfamiView protein in Pfam
PF00223. PsaA_PsaB. 1 hit.
PIRSFiPIRSF002905. PSI_A. 1 hit.
PRINTSiPR00257. PHOTSYSPSAAB.
SUPFAMiSSF81558. SSF81558. 1 hit.
TIGRFAMsiTIGR01335. psaA. 1 hit.
PROSITEiView protein in PROSITE
PS00419. PHOTOSYSTEM_I_PSAAB. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A405-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTISPPEREP KVRVVVDNDP VPTSFEKWAK PGHFDRTLAR GPQTTTWIWN
60 70 80 90 100
LHALAHDFDT HTSDLEDISR KIFSAHFGHL AVVFIWLSGM YFHGAKFSNY
110 120 130 140 150
EAWLADPTGI KPSAQVVWPI VGQGILNGDV GGGFHGIQIT SGLFQLWRAS
160 170 180 190 200
GITNEFQLYC TAIGGLVMAG LMLFAGWFHY HKRAPKLEWF QNVESMLNHH
210 220 230 240 250
LAGLLGLGSL AWAGHQIHVS LPINKLLDAG VAAKDIPLPH EFILNPSLMA
260 270 280 290 300
ELYPKVDWGF FSGVIPFFTF NWAAYSDFLT FNGGLNPVTG GLWLSDTAHH
310 320 330 340 350
HLAIAVLFII AGHMYRTNWG IGHSLKEILE AHKGPFTGAG HKGLYEVLTT
360 370 380 390 400
SWHAQLAINL AMMGSLSIIV AQHMYAMPPY PYLATDYPTQ LSLFTHHMWI
410 420 430 440 450
GGFLVVGGAA HGAIFMVRDY DPAMNQNNVL DRVLRHRDAI ISHLNWVCIF
460 470 480 490 500
LGFHSFGLYV HNDTMRAFGR PQDMFSDTGI QLQPVFAQWV QNLHTLAPGG
510 520 530 540 550
TAPNAAATAS VAFGGDVVAV GGKVAMMPIV LGTADFMVHH IHAFTIHVTV
560 570 580 590 600
LILLKGVLFA RSSRLIPDKA NLGFRFPCDG PGRGGTCQVS GWDHVFLGLF
610 620 630 640 650
WMYNCISVVI FHFSWKMQSD VWGTVAPDGT VSHITGGNFA QSAITINGWL
660 670 680 690 700
RDFLWAQASQ VIGSYGSALS AYGLLFLGAH FIWAFSLMFL FSGRGYWQEL
710 720 730 740 750
IESIVWAHNK LKVAPAIQPR ALSIIQGRAV GVAHYLLGGI ATTWAFFLAR

IISVG
Length:755
Mass (Da):83,183
Last modified:March 15, 2005 - v1
Checksum:i36A39CCE5D119AEA
GO

Sequence cautioni

The sequence BAC08282 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000039 Genomic DNA. Translation: BAC08282.1. Different initiation.
RefSeqiNP_681520.1. NC_004113.1.
WP_011056578.1. NC_004113.1.

Genome annotation databases

EnsemblBacteriaiBAC08282; BAC08282; BAC08282.
GeneIDi1011916.
KEGGitel:tlr0731.
PATRICifig|197221.4.peg.771.

Similar proteinsi

Entry informationi

Entry nameiPSAA_THEEB
AccessioniPrimary (citable) accession number: P0A405
Secondary accession number(s): P25896
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: September 27, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families