P0A3X5 (CAPP_THEEB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	tll1912

Organism

Thermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Thermosynechococcus › Thermosynechococcus elongatus

Protein attributes

Sequence length	1011 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity. HAMAP-Rule MF_00595
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation
Ligand	Magnesium
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1011	1011	Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595		PRO_0000166640
Sites
	Active site	207	1	By similarity
	Active site	658	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P0A3X5 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 0A11D4D01FE9E7FE	FASTA	1,011	116,427
	10 20 30 40 50 60 MTSVLDVTNR DRLIESESLA ARTLQERLRL VEEVLVDVLA AESGQELVDL LRRLGALSSP 70 80 90 100 110 120 EGHVLHAPEG ELLKVIESLE LNEAIRAARA FNLYFQIINI VEQHYEQQYN RERAAQEGLR 130 140 150 160 170 180 RRSVMSEPIS GVSGEGFPLP HTAANATDVR SGPSERLEHS LYEAIPATQQ YGSFAWLFPR 190 200 210 220 230 240 LQMLNVPPRH IQKLLDQLDI KLVFTAHPTE IVRQTIRDKQ RRVARLLEQL DVLEGASPHL 250 260 270 280 290 300 TDWNAQTLRA QLMEEIRLWW RTDELHQFKP EVLDEVEYTL HYFKEVIFAV IPKLYRRLEQ 310 320 330 340 350 360 SLHETFPALQ PPRHRFCRFG SWVGGDRDGN PYVKPEVTWQ TACYQRNLVL EEYIKSVERL 370 380 390 400 410 420 INLLSLSLHW CDVLPDLLDS LEQDQRQLPS IYEQYAVRYR QEPYRLKLAY VLKRLQNTRD 430 440 450 460 470 480 RNRALQTYCI RRNEAEELNN GQFYRHGEEF LAELLLIQRN LKETGLACRE LDDLICQVEV 490 500 510 520 530 540 FGFNLAALDI RQESTCHAEA LNEITAYLGI LPCPYTELSE AERTRWLLSE LSTRRPLIPG 550 560 570 580 590 600 ELPFSDRTNE IIETFRMVRQ LQQEFGTDLC NTYIISMSHE VSDLLEVLLF AKEAGLFDPA 610 620 630 640 650 660 TGASTLQAIP LFETVEDLKH APAVLTQLFS LPFCRSYLGS NSTPFLQEVM LGYSDSNKDS 670 680 690 700 710 720 GFLSSNWEIY KAQQQLQKIA ESFGFQLRIF HGRGGSVGRG GGPAYAAILA QPAQTIKGRI 730 740 750 760 770 780 KITEQGEVLA SKYSLPELAL FNLETVATAV IQASLLRSSI DEIEPWHEIM EELATRSRQC 790 800 810 820 830 840 YRHLIYEQPE FIEFFNEVTP IQEISQLQIS SRPTRRGGKK TLESLRAIPW VFSWTQTRFL 850 860 870 880 890 900 LPAWYGVGTA LKEFLEEKPA EHLSLLRYFY YKWPFFRMVI SKVEMTLAKV DLEIARYYVQ 910 920 930 940 950 960 ELSQPQNREA FCRLYDQIAQ EYRLTTELVL TITGHERLLD GDPALQRSVQ LRNRTIVPLG 970 980 990 1000 1010 FLQVSLLKRL RQHNSQTTSG AILRSRYGRG ELLRGALLTI NGIAAGMRNT G

References

[1]

"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000039 Genomic DNA. Translation: BAC09464.1.
RefSeq	NP_682702.1. NC_004113.1.
3D structure databases
ProteinModelPortal	P0A3X5.
ModBase	Search...
Protein-protein interaction databases
STRING	197221.tll1912.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC09464; BAC09464; BAC09464.
GeneID	1011076.
KEGG	tel:tll1912.
PATRIC	23929222. VBITheElo119873_2000.
Phylogenomic databases
eggNOG	COG2352.
HOGENOM	HOG000238647.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase-like_dom. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_THEEB

Accession

Primary (citable) accession number: P0A3X5
Secondary accession number(s): Q94QB2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	May 29, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program