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P0A3V3 (TR2M_RHIRD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tryptophan 2-monooxygenase
EC=1.13.12.3
Gene names
Name:tms1
Encoded onPlasmid pTiA6NC
OrganismRhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Taxonomic identifier358 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium › Agrobacterium tumefaciens complex

Protein attributes

Sequence length755 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O.

Pathway

Plant hormone metabolism; auxin biosynthesis.

Miscellaneous

The sequence shown is that of Ach5.

Sequence similarities

Belongs to the tryptophan 2-monooxygenase family.

Ontologies

Keywords
   Biological processAuxin biosynthesis
   DiseaseCrown gall tumor
   Molecular functionMonooxygenase
Oxidoreductase
   Technical termPlasmid
Gene Ontology (GO)
   Biological_processauxin biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functiontryptophan 2-monooxygenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 755755Tryptophan 2-monooxygenase
PRO_0000065587

Sequences

Sequence LengthMass (Da)Tools
P0A3V3 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 84D2A325594964D8

FASTA75583,892
        10         20         30         40         50         60 
MSASPLLDNQ CDHLPTKMVD LTMVDKADEL DRRVSDAFLE REASRGRRIT QISTECSAGL 

        70         80         90        100        110        120 
ACKRLADGRF PEISAGGKVA VLSAYIYIGK EILGRILESK PWARATVSGL VAIDLAPFCM 

       130        140        150        160        170        180 
DFSEAQLIQA LFLLSGKRCA PIDLSHFVAI SISKTAGFRT LPMPLYENGT MKCVTGFTIT 

       190        200        210        220        230        240 
LEGAVPFDMV AYGRNLMLKG SAGSFPTIDL LYDYRPFFDQ CSDSGRIGFF PEDVPKPKVA 

       250        260        270        280        290        300 
VIGAGISGLV VANELLHAGV DDVTIYEASD RVGGKLWSHA FRDAPSVVAE MGAMRFPPAA 

       310        320        330        340        350        360 
FCLFFFLERY GLSSMRPFPN PGTVDTYLVY QGVQYMWKAG QLPPKLFHRV YNGWRAFLKD 

       370        380        390        400        410        420 
GFYERDIVLA SPVAITQALK SGDIRWAHDS WQIWLNRFGR ESFSSGIERI FLGTHPPGGE 

       430        440        450        460        470        480 
TWSFPHDWDL FKLMGIGSGG FGPVFESGFI EILRLVINGY EENQRMCPEG ISELPRRIAS 

       490        500        510        520        530        540 
EVVNGVSVSQ RICHVQVRAI QKEKTKIKIR LKSGISELYD KVVVTSGLAN IQLRHCLTCD 

       550        560        570        580        590        600 
TNIFQAPVNQ AVDNSHMTGS SKLFLMTERK FWLDHILPSC VLMDGIAKAV YCLDYEPQDP 

       610        620        630        640        650        660 
NGKGLVLISY TWEDDSHKLL AVPDKKERLC LLRDAISRSF PAFAQHLFPA CADYDQNVIQ 

       670        680        690        700        710        720 
HDWLTDENAG GAFKLNRRGE DFYSEELFFQ ALDTANDTGV YLAGCSCSFT GGWVEGAIQT 

       730        740        750 
ACNAVCAIIH NCGGILAKGN PLEHSWKRYN YRTRN

« Hide

References

[1]"Nucleotide sequence of the tms genes of the pTiA6NC octopine Ti plasmid: two gene products involved in plant tumorigenesis."
Klee H., Montoya A., Horodyski F., Lichtenstein C., Garfinkel D., Fuller S., Flores C., Peschon J., Nester E., Gordon M.
Proc. Natl. Acad. Sci. U.S.A. 81:1728-1732(1984) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		K02554 Genomic DNA. Translation: AAA92550.1.
PIRQQAG4T. A04497.

3D structure databases

ProteinModelPortalP0A3V3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-7863.
UniPathwayUPA00151.

Family and domain databases

InterProIPR002937. Amino_oxidase.
IPR006064. Glycosidase.
IPR012142. Trp_2-mOase.
[Graphical view]
PfamPF01593. Amino_oxidase. 1 hit.
PF02027. RolB_RolC. 1 hit.
[Graphical view]
PIRSFPIRSF000319. Trp_2-mono_O2ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTR2M_RHIRD
AccessionPrimary (citable) accession number: P0A3V3
Secondary accession number(s): P04029
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 1986
Last sequence update: March 15, 2005
Last modified: April 3, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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