Reviewed, UniProtKB/Swiss-Prot P0A3V2 (TR2M_AGRT4)

Names and origin

Protein names

Recommended name:
    Tryptophan 2-monooxygenase
    EC=1.13.12.3

Gene names

Name:

tms1

Encoded on

Plasmid pTiAch5

Organism

Agrobacterium tumefaciens (strain Ach5)

Taxonomic identifier

176298 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	755 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O.
Pathway	Plant hormone metabolism; auxin biosynthesis.
Sequence similarities	Belongs to the tryptophan 2-monooxygenase family.

Ontologies

Keywords
Biological process	Auxin biosynthesis
Disease	Crown gall tumor
Molecular function	Monooxygenase Oxidoreductase
Technical term	Plasmid
Gene Ontology (GO)
Biological process	auxin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro tryptophan 2-monooxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 755	755	Tryptophan 2-monooxygenase		PRO_0000065586

Sequences

	Sequence		Length	Mass (Da)
	P0A3V2-1 [UniParc]. Last modified October 23, 1986. Version 1. Checksum: 9FD2B83FEA001A4D	FASTA	755	83,947
	10 20 30 40 50 60 MSASPLLDNQ CDHLPTKMVD LTMVDKADEL DRRVSDAFLE REASRGRRIT QISTECSAGL 70 80 90 100 110 120 ACKRLADGRF PEISAGGKVA VLSAYIYIGK EILGRILESK PWARATVSGL VAIDLAPFCM 130 140 150 160 170 180 DFSEAQLIQA LFLLSGKRCA PIDLSHFVAI SISKTAGFRT LPMPLYENGT MKCVTGFTIT 190 200 210 220 230 240 LEGAVPFDMV AYGRNLMLKG SAGSFPTIDL LYDYRPFFDQ CSDSGRIGFF PEDVPKPKVA 250 260 270 280 290 300 VIGAGISGLV VANELLHAGV DDVTIYEASD RVGGKLWSHA FRDAPSVVAE MGAMRFPPAA 310 320 330 340 350 360 FCLFFFLERY GLSSMRPFPN PGTVDTYLVY QGVQYMWKAG QLPPKLFHRV YNGWRAFLKD 370 380 390 400 410 420 GFYERDIVLA SPVAITQALK SGDIRWAHDS WQIWLNRFGR ESFSSGIERI FLGTHPPGGE 430 440 450 460 470 480 TWSFPHDWDL FKLMGIGSGG FGPVFESGFI EILRLVINGY EENQRMCPEG ISELPRRIAS 490 500 510 520 530 540 EVVNGVSVSQ RICHVQVRAI QKEKTKIKIR LKSGISELYD KVVVTSGLAN IQLRHCLTCD 550 560 570 580 590 600 TNIFQAPVNQ AVDNSHMTGS SKLFLMTERK FWLDHILPSC VLMDGIAKAV YCLDYEPQDP 610 620 630 640 650 660 NGKGLVLISY TWEDDSHKLL AVPDKKERLC LLRDAISRSF PAFAQHLFPA CADYDQNVIQ 670 680 690 700 710 720 HDWLTDENAG GAFKLNRRGE DFYSEELFFQ ALDTANDTGV YLAGCSCSFT GGWVEGANRT 730 740 750 PCNAVCAIIH NCGGILAKGN PLEHSWKRYN YRTRN

References

[1]

"The complete nucleotide sequence of the TL-DNA of the Agrobacterium tumefaciens plasmid pTiAch5." Gielen J., de Beuckeleer M., Seurinck J., Deboeck F., de Greve H., Lemmers M., van Montagu M., Schell J. EMBO J. 3:835-846(1984) [PubMed: 6327292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
PIR	QQAG4T. A04497.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR000759. Adrndx_reductase. IPR002937. Amino_oxidase. IPR006064. Glycosidase. IPR012142. Trp_2-mOase. [Graphical view]
Pfam	PF01593. Amino_oxidase. 1 hit. PF02027. RolB_RolC. 1 hit. [Graphical view]
PIRSF	PIRSF000319. Trp_2-mono_O2ase. 1 hit.
PRINTS	PR00419. ADXRDTASE.
ProtoNet	Search...

Entry information

Entry name

TR2M_AGRT4

Accession

Primary (citable) accession number: P0A3V2
Secondary accession number(s): P04029

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 1986
Last sequence update:	October 23, 1986
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)