P0A3U5 (OM31_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
31 kDa outer-membrane immunogenic protein

Gene names

Name:	omp31
Synonyms:	omp31-2
Ordered Locus Names:	BRA0423, BS1330_II0420

Organism

Brucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]

Taxonomic identifier

204722 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella suis

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Major outer membrane protein associated with peptidoglycans. May function as a porin.
Subunit structure	Oligomeric.
Subcellular location	Cell outer membrane.
Sequence similarities	Belongs to the Omp25/RopB family.

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal Transmembrane Transmembrane beta strand
Molecular function	Porin
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW pore complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	porin activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 240	221	31 kDa outer-membrane immunogenic protein		PRO_0000021885
Regions
	Region	48 – 83	36	Epitope recognized by the monoclonal antibody A59/10F09/G10

Sequences

	Sequence		Length	Mass (Da)
	P0A3U5 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 21C6E5EC479F66A5	FASTA	240	25,323
	10 20 30 40 50 60 MKSVILASIA AMFATSAMAA DVVVSEPSAP TAAPVDTFSW TGGYIGINAG YAGGKFKHPF 70 80 90 100 110 120 SSFDKEDNEQ VSGSLDVTAG GFVGGVQAGY NWQLDNGVVL GAETDFQGSS VTGSISAGAS 130 140 150 160 170 180 GLEGKAETKV EWFGTVRARL GYTATERLMV YGTGGLAYGK VKSAFNLGDD ASALHTWSDK 190 200 210 220 230 240 TKAGWTLGAG AEYAINNNWT LKSEYLYTDL GKRNLVDVDN SFLESKVNFH TVRVGLNYKF

References

[1]

"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts." Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

[2]

"Revised genome sequence of Brucella suis 1330." Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R. J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1330.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014292 Genomic DNA. Translation: AAN33618.1. CP002998 Genomic DNA. Translation: AEM19897.1.
RefSeq	NP_699613.1. NC_004311.2. YP_005614123.1. NC_017250.1.
3D structure databases
ProteinModelPortal	P0A3U5.
ModBase	Search...
Protein-protein interaction databases
STRING	204722.BRA0423.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN33618; AAN33618; BRA0423. AEM19897; AEM19897; BS1330_II0420.
GeneID	1164861. 12139855.
KEGG	bms:BRA0423. bsi:BS1330_II0420.
PATRIC	17793647. VBIBruSui107850_2639.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3637.
HOGENOM	HOG000135658.
KO	K16079.
OMA	PSIQRTI.
ProtClustDB	CLSK898963.
Family and domain databases
Gene3D	2.40.160.20. 1 hit.
InterPro	IPR017690. OM_insertion_C_omp85_target. IPR011250. OMP/PagP_b-brl. [Graphical view]
SUPFAM	SSF56925. SSF56925. 1 hit.
TIGRFAMs	TIGR03304. OMP85_target. 2 hits.
ProtoNet	Search...

Entry information

Entry name

OM31_BRUSU

Accession

Primary (citable) accession number: P0A3U5
Secondary accession number(s): G0KCF9, Q45322

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program