Reviewed, UniProtKB/Swiss-Prot P0A3P1 (OMP19_BRUME)

Names and origin

Protein names

Recommended name:
    Outer membrane lipoprotein omp19
Alternative name(s):
    Minor outer membrane protein omp19
    19 kDa OMP
    18 kDa immunoreactive antigen

Gene names

Name:	omp19
Ordered Locus Names:	BMEI0135

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell outer membrane; Lipid-anchor.
Miscellaneous	Elicits an immune response in humans, mice, sheep and goats infected with B.melitensis or B.abortus, but not in B.abortus-infected cattle.
Sequence similarities	Belongs to the rhizobiaceae omp19 lipoprotein family.

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	anchored to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell cell outer membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Probable
	Chain	21 – 177	157	Outer membrane lipoprotein omp19		PRO_0000018244
Amino acid modifications
	Lipidation	21	1	N-palmitoyl cysteine Probable
	Lipidation	21	1	S-diacylglycerol cysteine Probable

Sequences

	Sequence		Length	Mass (Da)
	P0A3P1-1 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 8038D5ABD87019E2	FASTA	177	17,604
	10 20 30 40 50 60 MGISKASLLS LAAAGIVLAG CQSSRLGNLD NVSPPPPPAP VNAVPAGTVQ KGNLDSPTQF 70 80 90 100 110 120 PNAPSTDMSA QSGTQVASLP PASAPDLTPG AVAGVWNASL GGQSCKIATP QTKYGQGYRA 130 140 150 160 170 GPLRCPGELA NLASWAVNGK QLVLYDANGG TVASLYSSGQ GRFDGQTTGG QAVTLSR

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008917 Genomic DNA. Translation: AAL51317.1.
PIR	AB3269.
RefSeq	NP_539053.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1195847.
GenomeReviews	Gene locus BMEI0135 in contig AE008917_GR.
KEGG	bme:BMEI0135.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P0A3P1.
OMA	CDMFLTL.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0135-MON.
Family and domain databases
InterPro	IPR010571. OM_lipoprot_Omp19_bac. [Graphical view]
Pfam	PF06604. OMP_19. 1 hit. [Graphical view]
PIRSF	PIRSF034005. OM_lipoprot_Omp19_bac. 1 hit.
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OMP19_BRUME

Accession

Primary (citable) accession number: P0A3P1
Secondary accession number(s): Q44663, Q44699

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)