P0A3L2 (IF3_LISIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-3

Gene names

Name:	infC
Ordered Locus Names:	lin1897

Organism

Listeria innocua serovar 6a (strain CLIP 11262) [Complete proteome] [HAMAP]

Taxonomic identifier

272626 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Listeriaceae › Listeria › Listeria innocua

Protein attributes

Sequence length	171 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the IF-3 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Translation initiation factor IF-3 HAMAP-Rule MF_00080		PRO_0000177536

Sequences

	Sequence		Length	Mass (Da)
	P0A3L2 [UniParc]. Last modified March 15, 2005. Version 1. Checksum: 66638EA70DFF48A3	FASTA	171	19,647
	10 20 30 40 50 60 MSKDMLVNDG IRAREVRLID QDGEQLGVKS KIDALQIAEK ANLDLVLVAP TAKPPVARIM 70 80 90 100 110 120 DYGKFRFEQQ KKDKEARKNQ KVIVMKEVRL SPTIDEHDFD TKLRNARKFL EKGDKVKCSI 130 140 150 160 170 RFKGRAITHK EIGQKVLDRF AKACEDLCTI EQRPKMDGRS MFLVLAPLHE K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIP 11262.
[2]	"The evolution of virulence determinants in Listeria genus." Ng E.Y., Goebel W. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-139. Strain: Serovar 6b.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL596170 Genomic DNA. Translation: CAC97127.1. AJ249401 Genomic DNA. Translation: CAC19093.1.
PIR	AG1669.
RefSeq	NP_471231.1. NC_003212.1.
3D structure databases
ProteinModelPortal	P0A3L2.
SMR	P0A3L2. Positions 3-78, 83-167.
ModBase	Search...
Protein-protein interaction databases
STRING	272626.lin1897.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAC97127; CAC97127; CAC97127.
GeneID	1130585.
KEGG	lin:lin1897.
PATRIC	20300605. VBILisInn102668_1941.
Organism-specific databases
GenoList	LIN1897.
CMR	Search...
Phylogenomic databases
eggNOG	COG0290.
HOGENOM	HOG000035157.
KO	K02520.
OMA	APKAPIN.
ProtClustDB	PRK00028.
Family and domain databases
Gene3D	3.10.20.80. 1 hit.
HAMAP	MF_00080. IF-3.
InterPro	IPR019813. Translation_initiation_fac3_CS. IPR001288. Translation_initiation_fac_3. IPR019815. Translation_initiation_fac_3_C. IPR019814. Translation_initiation_fac_3_N. [Graphical view]
PANTHER	PTHR10938. PTHR10938. 1 hit.
Pfam	PF00707. IF3_C. 1 hit. PF05198. IF3_N. 1 hit. [Graphical view]
SUPFAM	SSF54364. IF3. 1 hit. SSF55200. IF3. 1 hit.
TIGRFAMs	TIGR00168. infC. 1 hit.
PROSITE	PS00938. IF3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF3_LISIN

Accession

Primary (citable) accession number: P0A3L2
Secondary accession number(s): O53084, Q9EUW3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 15, 2005
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program