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P0A3G8 (HFQ_BRUSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-binding protein Hfq
Gene names
Name:hfq
Ordered Locus Names:BR1111, BS1330_I1107
OrganismBrucella suis biovar 1 (strain 1330) [Complete proteome] [HAMAP]
Taxonomic identifier204722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length78 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs By similarity. HAMAP-Rule MF_00436

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_00436

Sequence similarities

Belongs to the Hfq family.

Ontologies

Keywords
   Biological processStress response
   LigandRNA-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: InterPro

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7878RNA-binding protein Hfq HAMAP-Rule MF_00436
PRO_0000095630

Sequences

Sequence LengthMass (Da)Tools
P0A3G8 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 0D27DBD9CA161BD0

FASTA788,854
        10         20         30         40         50         60 
MAERSQNLQD LFLNSVRKQK ISLTIFLING VKLTGIVTSF DNFCVLLRRD GHSQLVYKHA 

        70 
ISTIMPSQPV QMFEGEEA 

« Hide

References

[1]"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M. expand/collapse author list , Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.
[2]"Revised genome sequence of Brucella suis 1330."
Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.
J. Bacteriol. 193:6410-6410(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014291 Genomic DNA. Translation: AAN30031.1.
CP002997 Genomic DNA. Translation: AEM18449.1.
RefSeqNP_698116.1. NC_004310.3.
YP_005615941.1. NC_017251.1.

3D structure databases

ProteinModelPortalP0A3G8.
SMRP0A3G8. Positions 7-71.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204722.BR1111.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN30031; AAN30031; BR1111.
AEM18449; AEM18449; BS1330_I1107.
GeneID1166787.
12138140.
KEGGbms:BR1111.
bsi:BS1330_I1107.
PATRIC17790554. VBIBruSui107850_1131.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1923.
HOGENOMHOG000004931.
KOK03666.
OMAQDPYLNV.
OrthoDBEOG68SW3W.

Family and domain databases

HAMAPMF_00436. Hfq.
InterProIPR005001. Hfq.
IPR010920. LSM_dom.
IPR001163. Ribonucl_LSM.
[Graphical view]
PfamPF01423. LSM. 1 hit.
[Graphical view]
SUPFAMSSF50182. SSF50182. 1 hit.
TIGRFAMsTIGR02383. Hfq. 1 hit.
ProtoNetSearch...

Other

PROP0A3G8.

Entry information

Entry nameHFQ_BRUSU
AccessionPrimary (citable) accession number: P0A3G8
Secondary accession number(s): G0KA33, Q9XBW1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella suis

Brucella suis (strain 1330): entries and gene names