Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P0A364 (CPSB_STRA5) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tyrosine-protein phosphatase CpsB

EC=3.1.3.48
Gene names
Name:cpsB
Synonyms:cpsIaB
Ordered Locus Names:SAG1174
OrganismStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) [Complete proteome] [HAMAP]
Taxonomic identifier208435 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length243 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Dephosphorylates CpsD. Involved in the regulation of capsular polysaccharide biosynthesis By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Cofactor

Manganese By similarity.

Pathway

Capsule biogenesis; capsule polysaccharide biosynthesis.

Sequence similarities

Belongs to the CpsB/CapC family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 243243Tyrosine-protein phosphatase CpsB
PRO_0000057890

Sequences

Sequence LengthMass (Da)Tools
P0A364 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 319CA48CCB310123

FASTA24328,600
        10         20         30         40         50         60 
MIDIHSHIVF DVDDGPKTLE ESLSLIEESY RQGVRIIVST SHRRKGMFET PEDIIFKNFS 

        70         80         90        100        110        120 
IVKHEAEKRF EHLQILYGGE LYYTSDMLEK LKLKQIPTLN NTKFALIEFS MQTSWKDIHT 

       130        140        150        160        170        180 
ALSNVLMLGI TPVVAHIERY NALENQKERV KEIINMGCYT QINSSHILKQ KLFNDKHKRF 

       190        200        210        220        230        240 
KKRARYFLEE NLVHFVASDM HNLDVRPPFL AEAYKIICRD FGKERANQLF IENAQSILKN 


HYI 

« Hide

References

« Hide 'large scale' references
[1]"Streptococcus agalactiae type V polysaccharide synthesis operon complete sequence."
McKinnon K., Chaffin D.O., Rubens C.E.
Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CNCTC 1/82 / Serotype V.
[2]"Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae."
Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.N., Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D., Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F. expand/collapse author list , Madupu R., Lewis M.R., Radune D., Fedorova N.B., Scanlan D., Khouri H.M., Mulligan S., Carty H.A., Cline R.T., Van Aken S.E., Gill J., Scarselli M., Mora M., Iacobini E.T., Brettoni C., Galli G., Mariani M., Vegni F., Maione D., Rinaudo D., Rappuoli R., Telford J.L., Kasper D.L., Grandi G., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-611 / 2603 V/R.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF349539 Genomic DNA. Translation: AAK29648.1.
AE009948 Genomic DNA. Translation: AAN00056.1.
RefSeqNP_688183.1. NC_004116.1.
YP_007968738.1. NC_021195.1.

3D structure databases

ProteinModelPortalP0A364.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208435.SAG1174.

Protocols and materials databases

DNASU1013981.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN00056; AAN00056; SAG1174.
GeneID1013981.
15485505.
KEGGsag:SAG1174.
sagl:GBS222_1004.
PATRIC19629184. VBIStrAga72745_1180.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000007624.
KOK01104.
OMATPHTLNG.
OrthoDBEOG6PKFDD.
ProtClustDBCLSK883942.

Enzyme and pathway databases

BioCycSAGA208435:GHVY-1268-MONOMER.
UniPathwayUPA00934.

Family and domain databases

InterProIPR016667. Caps_polysacc_synth_CpsB/CapC.
IPR004013. PHP_C.
[Graphical view]
PfamPF02811. PHP. 1 hit.
[Graphical view]
PIRSFPIRSF016557. Caps_synth_CpsB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCPSB_STRA5
AccessionPrimary (citable) accession number: P0A364
Secondary accession number(s): Q9S0S9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: April 16, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways