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P0A2K8 (GALF_SALTI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UTP--glucose-1-phosphate uridylyltransferase

EC=2.7.7.9
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name=UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene names
Name:galF
Ordered Locus Names:STY2308, t0774
OrganismSalmonella typhi [Complete proteome] [HAMAP]
Taxonomic identifier90370 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May play a role in stationary phase survival By similarity.

Catalytic activity

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathway

Carbohydrate metabolism; nucleotide-sugar metabolism.

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.

Sequence similarities

Belongs to the UDPGP type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297UTP--glucose-1-phosphate uridylyltransferase
PRO_0000201351

Sequences

Sequence LengthMass (Da)Tools
P0A2K8 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 94A85A18934511D4

FASTA29732,958
        10         20         30         40         50         60 
MMNLKAVIPV AGLGMHMLPA TKAIPKEMLP IVDKPMIQYI VDEIVAAGIK EIVLVTHASK 

        70         80         90        100        110        120 
NAVENHFDTS YELESLLEQR VKRQLLAEVQ SICPPGVTIM NVRQAQPLGL GHSILCARPV 

       130        140        150        160        170        180 
VGDNPFIVVL PDIIIDDATA DPLRYNLAAM VARFNETGRS QVLAKRMKGD LSEYSVIQTK 

       190        200        210        220        230        240 
EPLDNEGKVS RIVEFIEKPD QPQTLDSDLM AVGRYVLSAD IWAELERTEP GAWGRIQLTD 

       250        260        270        280        290 
AIAELAKKQS VDAMLMTGDS YDCGKKMGYM QAFVKYGLRN LKEGAKFRKS IEQLLHE 

« Hide

References

[1]"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18."
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P. expand/collapse author list , Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.
Nature 413:848-852(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CT18.
[2]"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700931 / Ty2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL513382 Genomic DNA. Translation: CAD02461.1.
AE014613 Genomic DNA. Translation: AAO68465.1.
RefSeqNP_456647.1. NC_003198.1.
NP_804616.1. NC_004631.1.

3D structure databases

ProteinModelPortalP0A2K8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING220341.STY2308.

Proteomic databases

PRIDEP0A2K8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO68465; AAO68465; t0774.
CAD02461; CAD02461; CAD02461.
GeneID1248643.
PATRIC18542557. VBISalEnt120419_2328.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1210.
HOGENOMHOG000283477.
KOK00963.
OMAKTHASIL.
OrthoDBEOG6Z9B3V.
ProtClustDBPRK10122.

Enzyme and pathway databases

UniPathwayUPA00030.
UPA00215.

Family and domain databases

InterProIPR005774. GalF.
IPR005835. NTP_transferase.
[Graphical view]
PfamPF00483. NTP_transferase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01105. galF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGALF_SALTI
AccessionPrimary (citable) accession number: P0A2K8
Secondary accession number(s): P26390
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways