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P0A2K7 (GALF_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UTP--glucose-1-phosphate uridylyltransferase

EC=2.7.7.9
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name=UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene names
Name:galF
Ordered Locus Names:STM2098
OrganismSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]
Taxonomic identifier99287 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May play a role in stationary phase survival.

Catalytic activity

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathway

Carbohydrate metabolism; nucleotide-sugar metabolism.

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.

Sequence similarities

Belongs to the UDPGP type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297UTP--glucose-1-phosphate uridylyltransferase
PRO_0000201352

Sequences

Sequence LengthMass (Da)Tools
P0A2K7 [UniParc].

Last modified March 15, 2005. Version 1.
Checksum: 94A85A18934511D4

FASTA29732,958
        10         20         30         40         50         60 
MMNLKAVIPV AGLGMHMLPA TKAIPKEMLP IVDKPMIQYI VDEIVAAGIK EIVLVTHASK 

        70         80         90        100        110        120 
NAVENHFDTS YELESLLEQR VKRQLLAEVQ SICPPGVTIM NVRQAQPLGL GHSILCARPV 

       130        140        150        160        170        180 
VGDNPFIVVL PDIIIDDATA DPLRYNLAAM VARFNETGRS QVLAKRMKGD LSEYSVIQTK 

       190        200        210        220        230        240 
EPLDNEGKVS RIVEFIEKPD QPQTLDSDLM AVGRYVLSAD IWAELERTEP GAWGRIQLTD 

       250        260        270        280        290 
AIAELAKKQS VDAMLMTGDS YDCGKKMGYM QAFVKYGLRN LKEGAKFRKS IEQLLHE 

« Hide

References

« Hide 'large scale' references
[1]"Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2)."
Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.
Mol. Microbiol. 5:695-713(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LT2.
[2]"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2."
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. expand/collapse author list , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.
Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X56793 Genomic DNA. Translation: CAA40114.1.
AE006468 Genomic DNA. Translation: AAL21002.1.
RefSeqNP_461043.1. NC_003197.1.

3D structure databases

ProteinModelPortalP0A2K7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING99287.STM2098.

Proteomic databases

PaxDbP0A2K7.
PRIDEP0A2K7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL21002; AAL21002; STM2098.
GeneID1253619.
KEGGstm:STM2098.
PATRIC32382779. VBISalEnt20916_2220.

Phylogenomic databases

eggNOGCOG1210.
HOGENOMHOG000283477.
KOK00963.
OMAMDEIMTN.
OrthoDBEOG6Z9B3V.
PhylomeDBP0A2K7.

Enzyme and pathway databases

BioCycSENT99287:GCTI-2110-MONOMER.
UniPathwayUPA00030.
UPA00215.

Family and domain databases

Gene3D3.90.550.10. 1 hit.
InterProIPR005774. GalF.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMSSF53448. SSF53448. 1 hit.
TIGRFAMsTIGR01105. galF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGALF_SALTY
AccessionPrimary (citable) accession number: P0A2K7
Secondary accession number(s): P26390
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: July 9, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways