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P0A2K7

- GALF_SALTY

UniProt

P0A2K7 - GALF_SALTY

Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene

galF

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (15 Mar 2005)
      Previous versions | rss
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    Functioni

    May play a role in stationary phase survival.

    Catalytic activityi

    UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

    Pathwayi

    GO - Molecular functioni

    1. enzyme regulator activity Source: InterPro
    2. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipopolysaccharide biosynthetic process Source: UniProtKB-UniPathway
    2. UDP-glucose metabolic process Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-2110-MONOMER.
    UniPathwayiUPA00030.
    UPA00215.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
    Alternative name(s):
    Alpha-D-glucosyl-1-phosphate uridylyltransferase
    UDP-glucose pyrophosphorylase
    Short name:
    UDPGP
    Uridine diphosphoglucose pyrophosphorylase
    Gene namesi
    Name:galF
    Ordered Locus Names:STM2098
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 297297UTP--glucose-1-phosphate uridylyltransferasePRO_0000201352Add
    BLAST

    Proteomic databases

    PaxDbiP0A2K7.
    PRIDEiP0A2K7.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM2098.

    Structurei

    3D structure databases

    ProteinModelPortaliP0A2K7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UDPGP type 2 family.Curated

    Phylogenomic databases

    eggNOGiCOG1210.
    HOGENOMiHOG000283477.
    KOiK00963.
    OMAiMDEIMTN.
    OrthoDBiEOG6Z9B3V.
    PhylomeDBiP0A2K7.

    Family and domain databases

    Gene3Di3.90.550.10. 1 hit.
    InterProiIPR005774. GalF.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view]
    PfamiPF00483. NTP_transferase. 1 hit.
    [Graphical view]
    SUPFAMiSSF53448. SSF53448. 1 hit.
    TIGRFAMsiTIGR01105. galF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0A2K7-1 [UniParc]FASTAAdd to Basket

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    MMNLKAVIPV AGLGMHMLPA TKAIPKEMLP IVDKPMIQYI VDEIVAAGIK    50
    EIVLVTHASK NAVENHFDTS YELESLLEQR VKRQLLAEVQ SICPPGVTIM 100
    NVRQAQPLGL GHSILCARPV VGDNPFIVVL PDIIIDDATA DPLRYNLAAM 150
    VARFNETGRS QVLAKRMKGD LSEYSVIQTK EPLDNEGKVS RIVEFIEKPD 200
    QPQTLDSDLM AVGRYVLSAD IWAELERTEP GAWGRIQLTD AIAELAKKQS 250
    VDAMLMTGDS YDCGKKMGYM QAFVKYGLRN LKEGAKFRKS IEQLLHE 297
    Length:297
    Mass (Da):32,958
    Last modified:March 15, 2005 - v1
    Checksum:i94A85A18934511D4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X56793 Genomic DNA. Translation: CAA40114.1.
    AE006468 Genomic DNA. Translation: AAL21002.1.
    RefSeqiNP_461043.1. NC_003197.1.
    WP_000981469.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL21002; AAL21002; STM2098.
    GeneIDi1253619.
    KEGGistm:STM2098.
    PATRICi32382779. VBISalEnt20916_2220.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X56793 Genomic DNA. Translation: CAA40114.1 .
    AE006468 Genomic DNA. Translation: AAL21002.1 .
    RefSeqi NP_461043.1. NC_003197.1.
    WP_000981469.1. NC_003197.1.

    3D structure databases

    ProteinModelPortali P0A2K7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM2098.

    Proteomic databases

    PaxDbi P0A2K7.
    PRIDEi P0A2K7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL21002 ; AAL21002 ; STM2098 .
    GeneIDi 1253619.
    KEGGi stm:STM2098.
    PATRICi 32382779. VBISalEnt20916_2220.

    Phylogenomic databases

    eggNOGi COG1210.
    HOGENOMi HOG000283477.
    KOi K00963.
    OMAi MDEIMTN.
    OrthoDBi EOG6Z9B3V.
    PhylomeDBi P0A2K7.

    Enzyme and pathway databases

    UniPathwayi UPA00030 .
    UPA00215 .
    BioCyci SENT99287:GCTI-2110-MONOMER.

    Family and domain databases

    Gene3Di 3.90.550.10. 1 hit.
    InterProi IPR005774. GalF.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view ]
    Pfami PF00483. NTP_transferase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53448. SSF53448. 1 hit.
    TIGRFAMsi TIGR01105. galF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2)."
      Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.
      Mol. Microbiol. 5:695-713(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: LT2.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.

    Entry informationi

    Entry nameiGALF_SALTY
    AccessioniPrimary (citable) accession number: P0A2K7
    Secondary accession number(s): P26390
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2005
    Last sequence update: March 15, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3