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Protein

Protein translocase subunit SecE

Gene

secE

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-4187-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecEUniRule annotation
Gene namesi
Name:secEUniRule annotation
Ordered Locus Names:STM4147
ORF Names:STMF1.6
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei16 – 36HelicalUniRule annotationAdd BLAST21
Transmembranei41 – 61HelicalUniRule annotationAdd BLAST21
Transmembranei96 – 116HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001041721 – 127Protein translocase subunit SecEAdd BLAST127

Proteomic databases

PaxDbiP0A2D3

Interactioni

Subunit structurei

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.UniRule annotation

Protein-protein interaction databases

STRINGi99287.STM4147

Family & Domainsi

Sequence similaritiesi

Belongs to the SecE/SEC61-gamma family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105PM1 Bacteria
COG0690 LUCA
HOGENOMiHOG000219148
KOiK03073
OMAiFLWLTDK
PhylomeDBiP0A2D3

Family and domain databases

Gene3Di1.20.5.1030, 1 hit
HAMAPiMF_00422 SecE, 1 hit
InterProiView protein in InterPro
IPR022943 SecE
IPR005807 SecE_bac
IPR038379 SecE_sf
IPR001901 Translocase_SecE/Sec61-g
PANTHERiPTHR33910 PTHR33910, 1 hit
PfamiView protein in Pfam
PF00584 SecE, 1 hit
PRINTSiPR01650 SECETRNLCASE
TIGRFAMsiTIGR00964 secE_bact, 1 hit
PROSITEiView protein in PROSITE
PS01067 SECE_SEC61G, 1 hit

Sequencei

Sequence statusi: Complete.

P0A2D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSANTEAQGS GRGLEAMKWI VVAILLIVAI VGNYLYRDMM LPLRALAVVI
60 70 80 90 100
LIAAAGGVAL LTTKGKATVA FAREARTEVR KVIWPTRQET LHTTLIVAAV
110 120
TAVMSLILWG LDGILVRLVS FITGLRF
Length:127
Mass (Da):13,689
Last modified:March 15, 2005 - v1
Checksum:i640DB5C2080E775D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF170176 Genomic DNA Translation: AAF33494.1
AE006468 Genomic DNA Translation: AAL22975.1
RefSeqiNP_463016.1, NC_003197.2
WP_001275691.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL22975; AAL22975; STM4147
GeneIDi1255673
KEGGistm:STM4147
PATRICifig|99287.12.peg.4359

Similar proteinsi

Entry informationi

Entry nameiSECE_SALTY
AccessioniPrimary (citable) accession number: P0A2D3
Secondary accession number(s): Q9L9K1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health