Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Exopolyphosphatase

Gene

ppx

Organism
Salmonella typhi
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain.By similarity

Catalytic activityi

(Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.By similarity

Cofactori

Mg2+By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
ExopolyphosphataseBy similarity (EC:3.6.1.11By similarity)
Short name:
ExopolyPaseBy similarity
Gene namesi
Name:ppx
Ordered Locus Names:STY2743, t0355
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002670 Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

Subcellular locationi

  • Cell membrane By similarity; Peripheral membrane protein By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001943042 – 513ExopolyphosphataseAdd BLAST512

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi220341.STY2743

Structurei

3D structure databases

ProteinModelPortaliP0A270
SMRiP0A270
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GppA/Ppx family.Curated

Phylogenomic databases

eggNOGiENOG4105C9X Bacteria
COG0248 LUCA
HOGENOMiHOG000258672
KOiK01524
OMAiRISEGCY

Family and domain databases

InterProiView protein in InterPro
IPR022371 Exopolyphosphatase
IPR003695 Ppx_GppA
IPR030673 PyroPPase_GppA_Ppx
PfamiView protein in Pfam
PF02541 Ppx-GppA, 1 hit
PIRSFiPIRSF001267 Pyrophosphatase_GppA_Ppx, 1 hit
TIGRFAMsiTIGR03706 exo_poly_only, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A270-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIYDKSPRP QEFAAVDLGS NSFHMVIARV VDGAMQIIGR LKQRVHLADG
60 70 80 90 100
LGADNKLSEE AMERGLSCLS LFAERLQGFS PSSVCIVGTH TLRQAQNAAD
110 120 130 140 150
FLKRAEKVIP YPIEIISGNE EARLIFMGVE HTQPEKGRKL VIDIGGGSTE
160 170 180 190 200
LVIGENFEPR LVESRRMGCV SFAQLYFPGG VINKENFQRA RMAAAQKLET
210 220 230 240 250
LTWQYRIQGW NVAMGASGTI KAAHEVLLAL GEKDGFITPE RLDKLKSEVL
260 270 280 290 300
KHRSFNALSL PGLSEERKAV FVPGLAILCG VFDALAIREL RLSDGALREG
310 320 330 340 350
VLYEMEGRFR HQDVRSRTAK SLANQYNIDR EQARRVLETT MQMYEQWQAQ
360 370 380 390 400
QPKLAHPQLE ALLRWAAMLH EVGLNINHSG LHRHSAYILQ HSDLPGFNQE
410 420 430 440 450
QQMMMATLVR YHRKAIKLDD MPRFTLFKKK QYLPLIQLLR LGVLLNNQRQ
460 470 480 490 500
ATTTPPTLRL TTDDSHWTLC FPHDWFSQNA LVLLDLEKEQ QYWEAVTGWR
510
LNIEEESSPE IAA
Length:513
Mass (Da):58,145
Last modified:January 23, 2007 - v2
Checksum:i02ACBA7895F2ED6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA Translation: CAD02704.1
AE014613 Genomic DNA Translation: AAO68074.1
RefSeqiNP_457037.1, NC_003198.1
WP_001123330.1, NZ_PHKG01000008.1

Genome annotation databases

EnsemblBacteriaiAAO68074; AAO68074; t0355
CAD02704; CAD02704; CAD02704
GeneIDi1249057
KEGGistt:t0355
sty:STY2743
PATRICifig|220341.7.peg.2781

Similar proteinsi

Entry informationi

Entry nameiPPX_SALTI
AccessioniPrimary (citable) accession number: P0A270
Secondary accession number(s): O86091
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 81 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health