Reviewed, UniProtKB/Swiss-Prot P0A230 (NIRD_SALTI)

Names and origin

Protein names

Recommended name:
    Nitrite reductase [NAD(P)H] small subunit
    EC=1.7.1.4

Gene names

Name:	nirD
Ordered Locus Names:	STY4321, t4030

Organism

Salmonella typhi [Complete proteome] [HAMAP]

Taxonomic identifier

90370 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for activity of the reductase By similarity.
Catalytic activity	Ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H.
Subunit structure	Associates with nirB By similarity.
Subcellular location	Cytoplasm By similarity.

Ontologies

Keywords
Biological process	Nitrate assimilation
Cellular component	Cytoplasm
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrate assimilation Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: InterPro electron carrier activity Inferred from electronic annotation. Source: InterPro nitrite reductase [NAD(P)H] activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 108	108	Nitrite reductase [NAD(P)H] small subunit		PRO_0000096856

Sequences

	Sequence		Length	Mass (Da)
	P0A230-1 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: 375C6D13AFF98161	FASTA	108	12,097
	10 20 30 40 50 60 MSQWQNICKI DDILPGTGVC ALSGGEQVAI FRPYHSDQVF AISNIDPFFE ASVLSRGLIA 70 80 90 100 EHQGELWVAS PLKKQRFRLS DGLCMEDEQF SVKHYDARVK DGVVQLRG

References

[1]

"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18." Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P. , Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:848-852(2001) [PubMed: 11677608] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CT18.

[2]

"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18." Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R. J. Bacteriol. 185:2330-2337(2003) [PubMed: 12644504] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700931 / Ty2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL627281 Genomic DNA. Translation: CAD08138.1. AE014613 Genomic DNA. Translation: AAO71499.1.
RefSeq	NP_458427.1. NP_807639.1.
3D structure databases
SMR	P0A230. Positions 1-108.
ModBase	Search...
Genome annotation databases
GeneID	1070948. 1250537.
GenomeReviews	Gene locus t4030 in contig AE014613_GR. Gene locus STY4321 in contig AL513382_GR.
KEGG	stt:t4030. sty:STY4321.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P0A230.
OMA	P0A230. GVCALVE.
Enzyme and pathway databases
BioCyc	SENT209261:T4030-MON. SENT220341:STY4321-MON.
BRENDA	1.7.1.4. 3716.
Family and domain databases
InterPro	IPR012748. Nitri_red_NirD. IPR017881. Nitrite_Rdtase_lsu_NirD_bac. IPR017941. Rieske_2Fe-2S. [Graphical view]
Gene3D	G3DSA:2.102.10.10. Rieske_reg. 1 hit.
TIGRFAMs	TIGR02378. nirD_assim_sml. 1 hit.
PROSITE	PS51300. NIRD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NIRD_SALTI

Accession

Primary (citable) accession number: P0A230
Secondary accession number(s): P40789

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	June 16, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)