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Protein

Protein MxiH

Gene

mxiH

Organism
Shigella flexneri
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Necessary for the secretion of IPA invasins.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport, Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MxiH
Gene namesi
Name:mxiH
Ordered Locus Names:CP0137
Encoded oniPlasmid pWR1004 Publications
Plasmid pCP3011 Publication
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000001006 Componenti: Plasmid pCP301

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000966591 – 83Protein MxiHAdd BLAST83

Proteomic databases

PaxDbiP0A223.
PRIDEiP0A223.

Interactioni

Protein-protein interaction databases

DIPiDIP-59026N.
STRINGi198214.CP0137.

Structurei

Secondary structure

183
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi22 – 39Combined sources18
Helixi44 – 78Combined sources35

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CA5X-ray2.10A/B1-78[»]
2V6Lelectron microscopy16.000/1/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z1-83[»]
3J0Relectron microscopy7.70A2-83[»]
ProteinModelPortaliP0A223.
SMRiP0A223.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A223.

Family & Domainsi

Sequence similaritiesi

Belongs to the MxiH/PrgI/YscF family.Curated

Phylogenomic databases

eggNOGiENOG4105Y7Q. Bacteria.
ENOG411262J. LUCA.
HOGENOMiHOG000076952.
KOiK03221.
OMAiKDWTLSS.

Family and domain databases

InterProiIPR021123. T3SS_needle-like.
IPR011841. T3SS_needle_YscF.
[Graphical view]
PfamiPF09392. T3SS_needle_F. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02105. III_needle. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A223-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTVPNDDW TLSSLSETFD DGTQTLQGEL TLALDKLAKN PSNPQLLAEY
60 70 80
QSKLSEYTLY RNAQSNTVKV IKDVDAAIIQ NFR
Length:83
Mass (Da):9,265
Last modified:March 1, 2005 - v1
Checksum:iBA4D517D145345DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M98390 Genomic DNA. Translation: AAA26530.1.
AL391753 Genomic DNA. Translation: CAC05812.1.
AF348706 Genomic DNA. Translation: AAK18456.1.
AF386526 Genomic DNA. Translation: AAL72553.1.
Z48957 Genomic DNA. Translation: CAA88823.1.
PIRiA45271.
RefSeqiNP_085300.1. NC_002698.1.
NP_858270.1. NC_004851.1.
WP_010921669.1. NZ_LVJC01000041.1.
YP_009062494.1. NC_024996.1.

Genome annotation databases

EnsemblBacteriaiAAL72553; AAL72553; SF_p0137.
GeneIDi1238256.
876534.
KEGGisfl:CP0137.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M98390 Genomic DNA. Translation: AAA26530.1.
AL391753 Genomic DNA. Translation: CAC05812.1.
AF348706 Genomic DNA. Translation: AAK18456.1.
AF386526 Genomic DNA. Translation: AAL72553.1.
Z48957 Genomic DNA. Translation: CAA88823.1.
PIRiA45271.
RefSeqiNP_085300.1. NC_002698.1.
NP_858270.1. NC_004851.1.
WP_010921669.1. NZ_LVJC01000041.1.
YP_009062494.1. NC_024996.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CA5X-ray2.10A/B1-78[»]
2V6Lelectron microscopy16.000/1/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z1-83[»]
3J0Relectron microscopy7.70A2-83[»]
ProteinModelPortaliP0A223.
SMRiP0A223.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59026N.
STRINGi198214.CP0137.

Proteomic databases

PaxDbiP0A223.
PRIDEiP0A223.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL72553; AAL72553; SF_p0137.
GeneIDi1238256.
876534.
KEGGisfl:CP0137.

Phylogenomic databases

eggNOGiENOG4105Y7Q. Bacteria.
ENOG411262J. LUCA.
HOGENOMiHOG000076952.
KOiK03221.
OMAiKDWTLSS.

Miscellaneous databases

EvolutionaryTraceiP0A223.

Family and domain databases

InterProiIPR021123. T3SS_needle-like.
IPR011841. T3SS_needle_YscF.
[Graphical view]
PfamiPF09392. T3SS_needle_F. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02105. III_needle. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMXIH_SHIFL
AccessioniPrimary (citable) accession number: P0A223
Secondary accession number(s): Q06079, Q6LAA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: November 30, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.