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Protein

Flagellar L-ring protein

Gene

flgH

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciSENT99287:GCTI-1189-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar L-ring protein
Alternative name(s):
Basal body L-ring protein
Gene namesi
Name:flgH
Synonyms:fla FVIII, flaY
Ordered Locus Names:STM1180
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 232211Flagellar L-ring proteinPRO_0000009471Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi22 – 221N-palmitoyl cysteineSequence analysis
Lipidationi22 – 221S-diacylglycerol cysteineSequence analysis

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP0A1N8.
PRIDEiP0A1N8.

Interactioni

Subunit structurei

The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

Protein-protein interaction databases

STRINGi99287.STM1180.

Family & Domainsi

Sequence similaritiesi

Belongs to the FlgH family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107W7W. Bacteria.
COG2063. LUCA.
HOGENOMiHOG000280165.
KOiK02393.
OMAiEGPLGNN.
OrthoDBiEOG6GTZJM.
PhylomeDBiP0A1N8.

Family and domain databases

HAMAPiMF_00415. FlgH.
InterProiIPR000527. Flag_Lring.
[Graphical view]
PfamiPF02107. FlgH. 1 hit.
[Graphical view]
PRINTSiPR01008. FLGLRINGFLGH.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A1N8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKYALHAYP VMALMVATLT GCAWIPAKPL VQGATTAQPI PGPVPVANGS
60 70 80 90 100
IFQSAQPINY GYQPLFEDRR PRNIGDTLTI VLQENVSASK SSSANASRDG
110 120 130 140 150
KTSFGFDTVP RYLQGLFGNS RADMEASGGN SFNGKGGANA SNTFSGTLTV
160 170 180 190 200
TVDQVLANGN LHVVGEKQIA INQGTEFIRF SGVVNPRTIS GSNSVPSTQV
210 220 230
ADARIEYVGN GYINEAQNMG WLQRFFLNLS PM
Length:232
Mass (Da):24,709
Last modified:March 15, 2005 - v1
Checksum:iA555EEF7BAB55E36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M24466 Genomic DNA. Translation: AAA27068.1.
AE006468 Genomic DNA. Translation: AAL20110.1.
X52094 Genomic DNA. Translation: CAA36315.1.
PIRiA32887. A30930.
RefSeqiNP_460151.1. NC_003197.1.
WP_001174897.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL20110; AAL20110; STM1180.
GeneIDi1252698.
KEGGistm:STM1180.
PATRICi32380807. VBISalEnt20916_1248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M24466 Genomic DNA. Translation: AAA27068.1.
AE006468 Genomic DNA. Translation: AAL20110.1.
X52094 Genomic DNA. Translation: CAA36315.1.
PIRiA32887. A30930.
RefSeqiNP_460151.1. NC_003197.1.
WP_001174897.1. NC_003197.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM1180.

Proteomic databases

PaxDbiP0A1N8.
PRIDEiP0A1N8.

Protocols and materials databases

DNASUi1252698.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL20110; AAL20110; STM1180.
GeneIDi1252698.
KEGGistm:STM1180.
PATRICi32380807. VBISalEnt20916_1248.

Phylogenomic databases

eggNOGiENOG4107W7W. Bacteria.
COG2063. LUCA.
HOGENOMiHOG000280165.
KOiK02393.
OMAiEGPLGNN.
OrthoDBiEOG6GTZJM.
PhylomeDBiP0A1N8.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-1189-MONOMER.

Family and domain databases

HAMAPiMF_00415. FlgH.
InterProiIPR000527. Flag_Lring.
[Graphical view]
PfamiPF02107. FlgH. 1 hit.
[Graphical view]
PRINTSiPR01008. FLGLRINGFLGH.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "L-, P-, and M-ring proteins of the flagellar basal body of Salmonella typhimurium: gene sequences and deduced protein sequences."
    Jones C.J., Homma M., Macnab R.M.
    J. Bacteriol. 171:3890-3900(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.
  3. "FlgB, FlgC, FlgF and FlgG. A family of structurally related proteins in the flagellar basal body of Salmonella typhimurium."
    Homma M., Kutsukake K., Hasebe M., Iino T., Macnab R.M.
    J. Mol. Biol. 211:465-477(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-7.

Entry informationi

Entry nameiFLGH_SALTY
AccessioniPrimary (citable) accession number: P0A1N8
Secondary accession number(s): P15929
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: March 15, 2005
Last modified: November 11, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.