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Protein

Flagellar hook protein FlgE

Gene

flgE

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciSENT99287:GCTI-1186-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar hook protein FlgE
Gene namesi
Name:flgE
Synonyms:fla FV, flaK
Ordered Locus Names:STM1177
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 403402Flagellar hook protein FlgEPRO_0000180827Add
BLAST

Proteomic databases

PaxDbiP0A1J1.
PRIDEiP0A1J1.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
fliKP264162EBI-6408688,EBI-6408664

Protein-protein interaction databases

IntActiP0A1J1. 1 interaction.
STRINGi99287.STM1177.

Structurei

Secondary structure

1
403
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi78 – 803Combined sources
Beta strandi82 – 865Combined sources
Beta strandi92 – 965Combined sources
Beta strandi99 – 1024Combined sources
Beta strandi115 – 1206Combined sources
Turni123 – 1264Combined sources
Beta strandi151 – 1599Combined sources
Beta strandi179 – 1879Combined sources
Beta strandi193 – 20412Combined sources
Beta strandi207 – 2148Combined sources
Beta strandi227 – 2326Combined sources
Beta strandi236 – 2405Combined sources
Beta strandi243 – 2475Combined sources
Beta strandi258 – 2625Combined sources
Beta strandi267 – 2715Combined sources
Beta strandi275 – 2817Combined sources
Beta strandi289 – 2946Combined sources
Beta strandi299 – 3046Combined sources
Beta strandi309 – 3157Combined sources
Beta strandi317 – 3193Combined sources
Helixi323 – 3253Combined sources
Beta strandi326 – 3283Combined sources
Turni338 – 3403Combined sources
Beta strandi344 – 3463Combined sources
Beta strandi360 – 3634Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WLGX-ray1.80A/B72-370[»]
2BGYelectron microscopy20.00A72-370[»]
2BGZelectron microscopy12.00A72-370[»]
3A69electron microscopy-A2-403[»]
ProteinModelPortaliP0A1J1.
SMRiP0A1J1. Positions 72-364.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A1J1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105BZE. Bacteria.
COG1749. LUCA.
HOGENOMiHOG000254240.
KOiK02390.
OMAiNLVNTQG.
OrthoDBiEOG6G7R1D.
PhylomeDBiP0A1J1.

Family and domain databases

InterProiIPR011491. Falgellar_hook_FlgE.
IPR001444. Flag_bb_rod_N.
IPR019776. Flagellar_basal_body_rod_CS.
IPR020013. Flagellar_FlgE/F/G.
IPR010930. Flg_bb/hook_C_dom.
[Graphical view]
PfamiPF07559. FlaE. 1 hit.
PF00460. Flg_bb_rod. 1 hit.
PF06429. Flg_bbr_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03506. FlgEFG_subfam. 1 hit.
PROSITEiPS00588. FLAGELLA_BB_ROD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A1J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFSQAVSGL NAAATNLDVI GNNIANSATY GFKSGTASFA DMFAGSKVGL
60 70 80 90 100
GVKVAGITQD FTDGTTTNTG RGLDVAISQN GFFRLVDSNG SVFYSRNGQF
110 120 130 140 150
KLDENRNLVN MQGMQLTGYP ATGTPPTIQQ GANPAPITIP NTLMAAKSTT
160 170 180 190 200
TASMQINLNS TDPVPSKTPF SVSDADSYNK KGTVTVYDSQ GNAHDMNVYF
210 220 230 240 250
VKTKDNEWAV YTHDSSDPAA TAPTTASTTL KFNENGILES GGTVNITTGT
260 270 280 290 300
INGATAATFS LSFLNSMQQN TGANNIVATN QNGYKPGDLV SYQINNDGTV
310 320 330 340 350
VGNYSNEQEQ VLGQIVLANF ANNEGLASQG DNVWAATQAS GVALLGTAGS
360 370 380 390 400
GNFGKLTNGA LEASNVDLSK ELVNMIVAQR NYQSNAQTIK TQDQILNTLV

NLR
Length:403
Mass (Da):42,210
Last modified:January 23, 2007 - v2
Checksum:iB64D5AF2BE5BD35C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X51737 Genomic DNA. Translation: CAA36022.1.
AE006468 Genomic DNA. Translation: AAL20107.1.
PIRiS10365.
RefSeqiNP_460148.1. NC_003197.1.
WP_000010567.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL20107; AAL20107; STM1177.
GeneIDi1252695.
KEGGistm:STM1177.
PATRICi32380801. VBISalEnt20916_1245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X51737 Genomic DNA. Translation: CAA36022.1.
AE006468 Genomic DNA. Translation: AAL20107.1.
PIRiS10365.
RefSeqiNP_460148.1. NC_003197.1.
WP_000010567.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WLGX-ray1.80A/B72-370[»]
2BGYelectron microscopy20.00A72-370[»]
2BGZelectron microscopy12.00A72-370[»]
3A69electron microscopy-A2-403[»]
ProteinModelPortaliP0A1J1.
SMRiP0A1J1. Positions 72-364.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP0A1J1. 1 interaction.
STRINGi99287.STM1177.

Proteomic databases

PaxDbiP0A1J1.
PRIDEiP0A1J1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL20107; AAL20107; STM1177.
GeneIDi1252695.
KEGGistm:STM1177.
PATRICi32380801. VBISalEnt20916_1245.

Phylogenomic databases

eggNOGiENOG4105BZE. Bacteria.
COG1749. LUCA.
HOGENOMiHOG000254240.
KOiK02390.
OMAiNLVNTQG.
OrthoDBiEOG6G7R1D.
PhylomeDBiP0A1J1.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-1186-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0A1J1.

Family and domain databases

InterProiIPR011491. Falgellar_hook_FlgE.
IPR001444. Flag_bb_rod_N.
IPR019776. Flagellar_basal_body_rod_CS.
IPR020013. Flagellar_FlgE/F/G.
IPR010930. Flg_bb/hook_C_dom.
[Graphical view]
PfamiPF07559. FlaE. 1 hit.
PF00460. Flg_bb_rod. 1 hit.
PF06429. Flg_bbr_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03506. FlgEFG_subfam. 1 hit.
PROSITEiPS00588. FLAGELLA_BB_ROD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Flagellar hook and hook-associated proteins of Salmonella typhimurium and their relationship to other axial components of the flagellum."
    Homma M., Derosier D.J., Macnab R.M.
    J. Mol. Biol. 213:819-832(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiFLGE_SALTY
AccessioniPrimary (citable) accession number: P0A1J1
Secondary accession number(s): P16322
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: January 23, 2007
Last modified: March 16, 2016
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.