ID IF3_PSESM Reviewed; 183 AA. AC P0A132; P52834; DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2005, sequence version 1. DT 27-MAR-2024, entry version 90. DE RecName: Full=Translation initiation factor IF-3 {ECO:0000255|HAMAP-Rule:MF_00080}; GN Name=infC {ECO:0000255|HAMAP-Rule:MF_00080}; GN OrderedLocusNames=PSPTO_2379; OS Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000). OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Pseudomonas. OX NCBI_TaxID=223283; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC BAA-871 / DC3000; RX PubMed=12928499; DOI=10.1073/pnas.1731982100; RA Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T., RA Gwinn M.L., Dodson R.J., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., RA Daugherty S.C., Brinkac L.M., Beanan M.J., Haft D.H., Nelson W.C., RA Davidsen T.M., Zafar N., Zhou L., Liu J., Yuan Q., Khouri H.M., RA Fedorova N.B., Tran B., Russell D., Berry K.J., Utterback T.R., RA Van Aken S.E., Feldblyum T.V., D'Ascenzo M., Deng W.-L., Ramos A.R., RA Alfano J.R., Cartinhour S., Chatterjee A.K., Delaney T.P., Lazarowitz S.G., RA Martin G.B., Schneider D.J., Tang X., Bender C.L., White O., Fraser C.M., RA Collmer A.; RT "The complete genome sequence of the Arabidopsis and tomato pathogen RT Pseudomonas syringae pv. tomato DC3000."; RL Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003). CC -!- FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the CC equilibrium between 70S ribosomes and their 50S and 30S subunits in CC favor of the free subunits, thus enhancing the availability of 30S CC subunits on which protein synthesis initiation begins. CC {ECO:0000255|HAMAP-Rule:MF_00080}. CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00080}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00080}. CC -!- SIMILARITY: Belongs to the IF-3 family. {ECO:0000255|HAMAP- CC Rule:MF_00080}. CC -!- SEQUENCE CAUTION: CC Sequence=AAO55890.1; Type=Erroneous initiation; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE016853; AAO55890.1; ALT_INIT; Genomic_DNA. DR RefSeq; NP_792195.1; NC_004578.1. DR AlphaFoldDB; P0A132; -. DR SMR; P0A132; -. DR STRING; 223283.PSPTO_2379; -. DR KEGG; pst:PSPTO_2379; -. DR PATRIC; fig|223283.9.peg.2414; -. DR eggNOG; COG0290; Bacteria. DR HOGENOM; CLU_054919_3_2_6; -. DR OrthoDB; 9806014at2; -. DR Proteomes; UP000002515; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule. DR Gene3D; 3.30.110.10; Translation initiation factor 3 (IF-3), C-terminal domain; 1. DR Gene3D; 3.10.20.80; Translation initiation factor 3 (IF-3), N-terminal domain; 1. DR HAMAP; MF_00080; IF_3; 1. DR InterPro; IPR036788; T_IF-3_C_sf. DR InterPro; IPR036787; T_IF-3_N_sf. DR InterPro; IPR019813; Translation_initiation_fac3_CS. DR InterPro; IPR001288; Translation_initiation_fac_3. DR InterPro; IPR019815; Translation_initiation_fac_3_C. DR InterPro; IPR019814; Translation_initiation_fac_3_N. DR NCBIfam; TIGR00168; infC; 1. DR PANTHER; PTHR10938; TRANSLATION INITIATION FACTOR IF-3; 1. DR PANTHER; PTHR10938:SF0; TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL; 1. DR Pfam; PF00707; IF3_C; 1. DR Pfam; PF05198; IF3_N; 1. DR SUPFAM; SSF55200; Translation initiation factor IF3, C-terminal domain; 1. DR SUPFAM; SSF54364; Translation initiation factor IF3, N-terminal domain; 1. DR PROSITE; PS00938; IF3; 1. PE 3: Inferred from homology; KW Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome. FT CHAIN 1..183 FT /note="Translation initiation factor IF-3" FT /id="PRO_0000177560" SQ SEQUENCE 183 AA; 20806 MW; 50ADD828F04831FE CRC64; MIIKREMRQD KRAAPKAPIN ENISAREVRL IGADGEQIGI VSIDEALRIA EEAKLDLVEI SADAVPPVCR VMDYGKSIFE KKKQVAAAKK NQKQIQVKEI KFRPGTEEGD YQVKLRNLVR FLSDGDRAKV SLRFRGREMA HQELGMELLK RVEGDLLEYG SVEQHPKMEG RQLIMVIAPK KKK //