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Protein

3-oxoadipate CoA-transferase subunit B

Gene

pcaJ

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.

Pathwayi: beta-ketoadipate pathway

This protein is involved in step 1 of the subpathway that synthesizes acetyl-CoA and succinyl-CoA from 3-oxoadipate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. 3-oxoadipate CoA-transferase subunit B (pcaJ)
  2. no protein annotated in this organism
This subpathway is part of the pathway beta-ketoadipate pathway, which is itself part of Aromatic compound metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA and succinyl-CoA from 3-oxoadipate, the pathway beta-ketoadipate pathway and in Aromatic compound metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei50PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Enzyme and pathway databases

UniPathwayiUPA00157; UER00262.

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoadipate CoA-transferase subunit B (EC:2.8.3.6)
Alternative name(s):
Beta-ketoadipate:succinyl-CoA transferase subunit B
Gene namesi
Name:pcaJ
Ordered Locus Names:PP_3952
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001579182 – 2133-oxoadipate CoA-transferase subunit BAdd BLAST212

Proteomic databases

PRIDEiP0A101.

Interactioni

Subunit structurei

Heterodimer.By similarity

Protein-protein interaction databases

STRINGi160488.PP_3952.

Structurei

3D structure databases

ProteinModelPortaliP0A101.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107QNJ. Bacteria.
COG2057. LUCA.
HOGENOMiHOG000221245.
KOiK01032.
OMAiANWRVGS.

Family and domain databases

InterProiIPR012791. 3-oxoacid_CoA-transf_B.
IPR004165. CoA_trans_fam_I.
IPR004164. CoA_transf_AS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02428. pcaJ_scoB_fam. 1 hit.
PROSITEiPS01274. COA_TRANSF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A101-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITKKLSRT EMAQRVAADI QEGAYVNLGI GAPTLVANYL GDKEVFLHSE
60 70 80 90 100
NGLLGMGPSP APGEEDDDLI NAGKQHVTLL TGGAFFHHAD SFSMMRGGHL
110 120 130 140 150
DIAVLGAFQV SVKGDLANWH TGAEGSIPAV GGAMDLATGA RQVFVMMDHL
160 170 180 190 200
TKTGESKLVP ECTYPLTGIA CVSRIYTDLA VLEVTPEGLK VVEICADIDF
210
DELQKLSGVP LIK
Length:213
Mass (Da):22,552
Last modified:January 23, 2007 - v2
Checksum:i5071B33173AD8B7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN69546.1.
RefSeqiNP_746082.1. NC_002947.4.
WP_003251131.1. NC_002947.4.

Genome annotation databases

GeneIDi1046612.
KEGGippu:PP_3952.
PATRICi19946530. VBIPsePut30601_4210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN69546.1.
RefSeqiNP_746082.1. NC_002947.4.
WP_003251131.1. NC_002947.4.

3D structure databases

ProteinModelPortaliP0A101.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_3952.

Proteomic databases

PRIDEiP0A101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1046612.
KEGGippu:PP_3952.
PATRICi19946530. VBIPsePut30601_4210.

Phylogenomic databases

eggNOGiENOG4107QNJ. Bacteria.
COG2057. LUCA.
HOGENOMiHOG000221245.
KOiK01032.
OMAiANWRVGS.

Enzyme and pathway databases

UniPathwayiUPA00157; UER00262.

Family and domain databases

InterProiIPR012791. 3-oxoacid_CoA-transf_B.
IPR004165. CoA_trans_fam_I.
IPR004164. CoA_transf_AS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02428. pcaJ_scoB_fam. 1 hit.
PROSITEiPS01274. COA_TRANSF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPCAJ_PSEPK
AccessioniPrimary (citable) accession number: P0A101
Secondary accession number(s): Q01104
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.