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Protein

Outer membrane protein class 4

Gene

rmpM

Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Porin

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

BioCyciNMEN122587:GI3Q-1940-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein class 4
Gene namesi
Name:rmpM
Ordered Locus Names:NMA2105
OrganismiNeisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Taxonomic identifieri122587 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000000626 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 242220Outer membrane protein class 4PRO_0000020111Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi191 ↔ 214By similarity

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

1
242
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi92 – 1009Combined sources
Helixi101 – 1055Combined sources
Beta strandi108 – 1103Combined sources
Helixi114 – 12714Combined sources
Beta strandi132 – 1409Combined sources
Beta strandi143 – 1453Combined sources
Helixi147 – 16721Combined sources
Helixi172 – 1743Combined sources
Beta strandi175 – 1795Combined sources
Turni181 – 1844Combined sources
Helixi188 – 1969Combined sources
Helixi206 – 2149Combined sources
Helixi216 – 2183Combined sources
Beta strandi219 – 22810Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1R1MX-ray1.90A87-242[»]
ProteinModelPortaliP0A0V2.
SMRiP0A0V2. Positions 90-229.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A0V2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati69 – 7021
Repeati71 – 7222
Repeati73 – 7423
Repeati75 – 7624
Repeati77 – 7825
Repeati79 – 8026
Repeati81 – 8227
Domaini92 – 229138OmpA-likePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni69 – 82147 X 2 AA tandem repeats of X-PAdd
BLAST

Sequence similaritiesi

Belongs to the OmpA family.Curated
Contains 1 OmpA-like domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

HOGENOMiHOG000189913.
OMAiCWRTGYW.

Family and domain databases

CDDicd07185. OmpA_C-like. 1 hit.
Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006664. OMP_bac.
IPR006665. OmpA-like.
IPR006690. OMPA-like_CS.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
PRINTSiPR01021. OMPADOMAIN.
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiPS01068. OMPA_1. 1 hit.
PS51123. OMPA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A0V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKQLKLSAL FVALLASGTA VAGEASVQGY TVSGQSNEIV RNNYGECWKN
60 70 80 90 100
AYFDKASQGR VECGDAVAAP EPEPEPEPAP APVVVVEQAP QYVDETISLS
110 120 130 140 150
AKTLFGFDKD SLRAEAQDNL KVLAQRLGQT NIQSVRVEGH TDFMGSDKYN
160 170 180 190 200
QALSERRAYV VANNLVSNGV PVSRISAVGL GESQAQMTQV CEAEVAKLGA
210 220 230 240
KVSKAKKREA LIACIEPDRR VDVKIRSIVT RQVVPAHNHH QH
Length:242
Mass (Da):26,141
Last modified:March 1, 2005 - v1
Checksum:i5CCAA490236B1D62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157959 Genomic DNA. Translation: CAM09205.1.
PIRiA81782.
RefSeqiWP_002226062.1. NC_003116.1.

Genome annotation databases

EnsemblBacteriaiCAM09205; CAM09205; NMA2105.
KEGGinma:NMA2105.
PATRICi20365708. VBINeiMen132687_2544.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157959 Genomic DNA. Translation: CAM09205.1.
PIRiA81782.
RefSeqiWP_002226062.1. NC_003116.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1R1MX-ray1.90A87-242[»]
ProteinModelPortaliP0A0V2.
SMRiP0A0V2. Positions 90-229.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM09205; CAM09205; NMA2105.
KEGGinma:NMA2105.
PATRICi20365708. VBINeiMen132687_2544.

Phylogenomic databases

HOGENOMiHOG000189913.
OMAiCWRTGYW.

Enzyme and pathway databases

BioCyciNMEN122587:GI3Q-1940-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0A0V2.

Family and domain databases

CDDicd07185. OmpA_C-like. 1 hit.
Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006664. OMP_bac.
IPR006665. OmpA-like.
IPR006690. OMPA-like_CS.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
PRINTSiPR01021. OMPADOMAIN.
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiPS01068. OMPA_1. 1 hit.
PS51123. OMPA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOMP4_NEIMA
AccessioniPrimary (citable) accession number: P0A0V2
Secondary accession number(s): A1ITT6, P38367
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.