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P0A0T1 (G6PI_XANCI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
OrganismXanthomonas campestris pv. citri (Xanthomonas citri)
Taxonomic identifier346 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length504 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for pathogenicity. HAMAP-Rule MF_00473

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Induction

Inhibited by growth in complex medium but induced by culture in plant extract. HAMAP-Rule MF_00473

Miscellaneous

Mutation in pgi results in the inability of X.c.citri to utilize fructose or glycerol as carbon sources, to grow in plant tissue, and to cause typical canker symptoms.

Sequence similarities

Belongs to the GPI family.

Sequence caution

The sequence AAC08426.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 504504Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180771

Sites

Active site3331Proton donor By similarity
Active site3641 By similarity
Active site4731 By similarity

Sequences

Sequence LengthMass (Da)Tools
P0A0T1 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 03C410C3F8E8A504

FASTA50454,454
        10         20         30         40         50         60 
MTQTNGFDAL HAHAQRLRGA AIPALLAAEP ERPTQYARQV GPLYFNFARQ KYDRAALDAL 

        70         80         90        100        110        120 
FAIARERDLS GAFQRLFRGE QVNVTEQRAA LHTALRGDLT DAPVASEAYA TAEEVRQRMG 

       130        140        150        160        170        180 
SLIQQLEATD VTDIVSVGIG GSDLGPRLVA DALRAPSGAR FRVHFVSNVD GAAMQRTLAT 

       190        200        210        220        230        240 
LDPARTAGIL ISKTFGTQET LLNGSILHAW LGGSERLYAV SANPERAAKA FDIAPGRVLP 

       250        260        270        280        290        300 
MWDWVGGRYS LWSAVGFPIA LAIGFERFEQ LLEGAAQFDA HVLNTPLEEN VAVLHGLTAV 

       310        320        330        340        350        360 
WNRNLLGSAT HAVMTYDQRL ALLPAYLQQL VMESLGKRVK LDGSAVDSDT VSVWWGGAGT 

       370        380        390        400        410        420 
DVQHSFFQAL HQGTSVVPAD FIGTVHNDDP YAENHTALMA NVLAQTEALA NGQDSSDPHR 

       430        440        450        460        470        480 
SYPGGRPSTV ILLDALTPQA LGALISMYEH SVYVQSVMWG INAFDQFGVE LGKQLASQLL 

       490        500 
PALKGESVDV ADPVTRELLN KLRG 

« Hide

References

[1]"Requirement for phosphoglucose isomerase of Xanthomonas campestris in pathogenesis of citrus canker."
Tung S.Y., Kuo T.T.
Appl. Environ. Microbiol. 65:5564-5570(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
Strain: XW47.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF054807 Genomic DNA. Translation: AAC08426.1. Different initiation.
PIRT46970.

3D structure databases

ProteinModelPortalP0A0T1.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP0A0T1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_XANCI
AccessionPrimary (citable) accession number: P0A0T1
Secondary accession number(s): O68824
Entry history
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: June 11, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways