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P0A0Q5 (ACPS_NEIMB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Holo-[acyl-carrier-protein] synthase

Short name=Holo-ACP synthase
EC=2.7.8.7
Alternative name(s):
4'-phosphopantetheinyl transferase AcpS
Gene names
Name:acpS
Synonyms:dpj
Ordered Locus Names:NMB0452
OrganismNeisseria meningitidis serogroup B (strain MC58) [Reference proteome] [HAMAP]
Taxonomic identifier122586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length125 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP-Rule MF_00101

Catalytic activity

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP-Rule MF_00101

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00101

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00101.

Sequence similarities

Belongs to the P-Pant transferase superfamily. AcpS family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 125125Holo-[acyl-carrier-protein] synthase HAMAP-Rule MF_00101
PRO_0000175677

Sites

Metal binding81Magnesium By similarity
Metal binding571Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
P0A0Q5 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 64AD823F8529EC6A

FASTA12513,677
        10         20         30         40         50         60 
MIYGIGTDIV SLKRIIRLNK KFGQAFAGRI LTPEELLEFP QAGKPVNYLA KRFAAKEAFA 

        70         80         90        100        110        120 
KAVGTGIRGA VSFRNIGIGH DALGKPEFFY GPALSKWLEE QGISRVSLSM SDEEDTVLAF 


VVAEK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE002098 Genomic DNA. Translation: AAF40889.1.
PIRF81197.
RefSeqNP_273499.1. NC_003112.2.

3D structure databases

ProteinModelPortalP0A0Q5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING122586.NMB0452.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF40889; AAF40889; NMB0452.
GeneID902568.
KEGGnme:NMB0452.
PATRIC20356118. VBINeiMen85645_0575.

Phylogenomic databases

eggNOGCOG0736.
HOGENOMHOG000014316.
KOK00997.
OMAVAHVHVT.
OrthoDBEOG6384R9.
ProtClustDBPRK00070.

Enzyme and pathway databases

BioCycNMEN122586:GHGG-476-MONOMER.

Family and domain databases

Gene3D3.90.470.20. 1 hit.
HAMAPMF_00101. AcpS.
InterProIPR008278. 4-PPantetheinyl_Trfase_SF.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase_dom.
[Graphical view]
PfamPF01648. ACPS. 1 hit.
[Graphical view]
ProDomPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56214. SSF56214. 1 hit.
TIGRFAMsTIGR00516. acpS. 1 hit.
TIGR00556. pantethn_trn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPS_NEIMB
AccessionPrimary (citable) accession number: P0A0Q5
Secondary accession number(s): Q9RML8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families