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P0A0L4 (ENTC3_STAAN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Enterotoxin type C-3
Alternative name(s):
SEC3
Gene names
Name:entC3
Ordered Locus Names:SA1817
OrganismStaphylococcus aureus (strain N315) [Complete proteome] [HAMAP]
Taxonomic identifier158879 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.

Subcellular location

Secreted.

Sequence similarities

Belongs to the staphylococcal/streptococcal toxin family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionEnterotoxin
Superantigen
Toxin
   PTMDisulfide bond
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 By similarity
Chain28 – 266239Enterotoxin type C-3
PRO_0000035610

Amino acid modifications

Disulfide bond120 ↔ 137 By similarity

Sequences

Sequence LengthMass (Da)Tools
P0A0L4 [UniParc].

Last modified March 1, 2005. Version 1.
Checksum: 5ED8A32D11FFCA59

FASTA26630,671
        10         20         30         40         50         60 
MYKRLFISRV ILIFALILVI STPNVLAESQ PDPMPDDLHK SSEFTGTMGN MKYLYDDHYV 

        70         80         90        100        110        120 
SATKVKSVDK FLAHDLIYNI SDKKLKNYDK VKTELLNEDL AKKYKDEVVD VYGSNYYVNC 

       130        140        150        160        170        180 
YFSSKDNVGK VTGGKTCMYG GITKHEGNHF DNGNLQNVLV RVYENKRNTI SFEVQTDKKS 

       190        200        210        220        230        240 
VTAQELDIKA RNFLINKKNL YEFNSSPYET GYIKFIENNG NTFWYDMMPA PGDKFDQSKY 

       250        260 
LMMYNDNKTV DSKSVKIEVH LTTKNG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000018 Genomic DNA. Translation: BAB43097.1.
RefSeqNP_375118.1. NC_002745.2.

3D structure databases

ProteinModelPortalP0A0L4.
SMRP0A0L4. Positions 28-266.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING158879.SA1817.

Protein family/group databases

Allergome2141. Sta a SEC.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB43097; BAB43097; BAB43097.
GeneID1124709.
KEGGsau:SA1817.
PATRIC19576068. VBIStaAur116463_1966.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG12203.
HOGENOMHOG000232691.
KOK11040.
OMAGLMENMK.
OrthoDBEOG6H4K5S.
ProtClustDBCLSK885720.

Enzyme and pathway databases

BioCycSAUR158879:GJCB-1941-MONOMER.

Family and domain databases

Gene3D3.10.20.120. 1 hit.
InterProIPR008992. Enterotoxin_bac.
IPR006126. Staph/Strept_toxin_CS.
IPR006173. Staph_tox_OB.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
IPR006177. Toxin_bac.
[Graphical view]
PfamPF02876. Stap_Strp_tox_C. 1 hit.
PF01123. Stap_Strp_toxin. 1 hit.
[Graphical view]
PRINTSPR00279. BACTRLTOXIN.
PR01898. SAGSUPRFAMLY.
SUPFAMSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEPS00277. STAPH_STREP_TOXIN_1. 1 hit.
PS00278. STAPH_STREP_TOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP0A0L4.

Entry information

Entry nameENTC3_STAAN
AccessionPrimary (citable) accession number: P0A0L4
Secondary accession number(s): P23313
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: November 13, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families