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Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Staphylococcus aureus (strain NCTC 8325)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Stereospecific for the R isomer of MetO.

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei114NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciSAUR93061:G1G5Y-1334-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrB (EC:1.8.4.12)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductase
Gene namesi
Name:msrB
Synonyms:pilB
Ordered Locus Names:SAOUHSC_01431
OrganismiStaphylococcus aureus (strain NCTC 8325)
Taxonomic identifieri93061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001402991 – 142Peptide methionine sulfoxide reductase MsrBAdd BLAST142

Interactioni

Protein-protein interaction databases

STRINGi93061.SAOUHSC_01431

Structurei

3D structure databases

ProteinModelPortaliP0A088
SMRiP0A088
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 125MsrBPROSITE-ProRule annotationAdd BLAST124

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105E0X Bacteria
COG0229 LUCA
HOGENOMiHOG000243425
KOiK07305
OMAiYKASHKF

Family and domain databases

HAMAPiMF_01400 MsrB, 1 hit
InterProiView protein in InterPro
IPR028427 Met_Sox_Rdtase
IPR002579 Met_Sox_Rdtase_MsrB
IPR011057 Mss4-like_sf
PANTHERiPTHR10173 PTHR10173, 1 hit
PfamiView protein in Pfam
PF01641 SelR, 1 hit
SUPFAMiSSF51316 SSF51316, 1 hit
TIGRFAMsiTIGR00357 TIGR00357, 1 hit
PROSITEiView protein in PROSITE
PS51790 MSRB, 1 hit

Sequencei

Sequence statusi: Complete.

P0A088-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKDKSELT DIEYIVTQEN GTEPPFMNEY WNHFAKGIYV DKISGKPLFT
60 70 80 90 100
SEEKFHSECG WPSFSKALDD DEIIELVDKS FGMLRTEVRS EESNSHLGHV
110 120 130 140
FNDGPKESGG LRYCINSAAI QFIPYEKLEE LGYGDLISHF DK
Length:142
Mass (Da):16,277
Last modified:February 15, 2005 - v1
Checksum:i8B8DD1390D9F80AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF349112 Genomic DNA Translation: AAK83252.1
CP000253 Genomic DNA Translation: ABD30523.1
RefSeqiWP_000913315.1, NC_007795.1
YP_499956.1, NC_007795.1

Genome annotation databases

EnsemblBacteriaiABD30523; ABD30523; SAOUHSC_01431
GeneIDi3920212
KEGGisao:SAOUHSC_01431
PATRICifig|93061.5.peg.1307

Similar proteinsi

Entry informationi

Entry nameiMSRB_STAA8
AccessioniPrimary (citable) accession number: P0A088
Secondary accession number(s): Q2FYK9, Q93P62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: February 15, 2005
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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