P09925 (SURF1_MOUSE) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 100.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Surfeit locus protein 1 | ||||
| Gene names |
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| Organism | Mus musculus (Mouse) [Reference proteome] | ||||
| Taxonomic identifier | 10090 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus![]() |
Protein attributes
| Sequence length | 306 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Probably involved in the biogenesis of the COX complex By similarity. |
| Subcellular location | Mitochondrion inner membrane; Multi-pass membrane protein By similarity. |
| Sequence similarities | Belongs to the SURF1 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane Mitochondrion Mitochondrion inner membrane |
| Domain | Transmembrane Transmembrane helix |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | ATP biosynthetic process Inferred from electronic annotation. Source: Compara oxidative phosphorylationInferred from electronic annotation. Source: Compara |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial inner membraneInferred from electronic annotation. Source: UniProtKB-SubCell mitochondrionInferred from direct assay PubMed 14651853PubMed 18614015. Source: MGI |
| Molecular_function | cytochrome-c oxidase activity Inferred from mutant phenotype PubMed 12566387. Source: MGI |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 306 | 306 | Surfeit locus protein 1 | PRO_0000215653 | |||||
Regions | |||||||||
| Transmembrane | 68 – 86 | 19 | Helical; Potential | ||||||
| Transmembrane | 280 – 300 | 21 | Helical; Potential | ||||||
Experimental info | |||||||||
| Sequence conflict | 9 | 1 | V → G in AAA40153. Ref.1 | ||||||
| Sequence conflict | 14 | 1 | M → I in BAB22123. Ref.3 | ||||||
| Sequence conflict | 284 | 1 | W → CR in AAA40153. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units." Williams T.J., Fried M. Mol. Cell. Biol. 6:4558-4569(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | Fried M. Submitted (SEP-1988) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION. |
| [3] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y.Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Kidney. |
| [4] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M14689 Genomic DNA. Translation: AAA40153.1. AK002469 mRNA. Translation: BAB22123.1. BC004755 mRNA. Translation: AAH04755.1. |
| IPI | IPI00319135. |
| PIR | B25394. |
| RefSeq | NP_001258653.1. NM_001271724.1. NP_038705.2. NM_013677.2. |
| UniGene | Mm.347512. |
3D structure databases | |
| ProteinModelPortal | P09925. |
| ModBase | Search... |
PTM databases | |
| PhosphoSite | P09925. |
Proteomic databases | |
| PaxDb | P09925. |
| PRIDE | P09925. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUST00000167661; ENSMUSP00000128488; ENSMUSG00000015790. |
| GeneID | 20930. |
| KEGG | mmu:20930. |
Organism-specific databases | |
| CTD | 6834. |
| MGI | MGI:98443. Surf1. |
Phylogenomic databases | |
| eggNOG | COG3346. |
| GeneTree | ENSGT00530000064194. |
| HOVERGEN | HBG058486. |
| InParanoid | P09925. |
| KO | K14998. |
| OrthoDB | EOG4BZN3D. |
Gene expression databases | |
| ArrayExpress | P09925. |
| Bgee | P09925. |
| CleanEx | MM_SURF1. |
| Genevestigator | P09925. |
| GermOnline | ENSMUSG00000015790. Mus musculus. |
Family and domain databases | |
| InterPro | IPR002994. Surf1/Shy1. [Graphical view] |
| PANTHER | PTHR23427:SF2. PTHR23427:SF2. 1 hit. |
| Pfam | PF02104. SURF1. 1 hit. [Graphical view] |
| PROSITE | PS50895. SURF1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 299855. |
| SOURCE | Search... |
Entry information
| Entry name | SURF1_MOUSE | ||||||||
| Accession | Primary (citable) accession number: P09925 Secondary accession number(s): Q99KB4, Q9DCU5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

Clusters with
