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P09925

- SURF1_MOUSE

UniProt

P09925 - SURF1_MOUSE

Protein

Surfeit locus protein 1

Gene

Surf1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 110 (01 Oct 2014)
      Sequence version 3 (06 Jun 2002)
      Previous versions | rss
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    Functioni

    Probably involved in the biogenesis of the COX complex.By similarity

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: MGI

    GO - Biological processi

    1. ATP biosynthetic process Source: Ensembl
    2. hydrogen ion transmembrane transport Source: GOC
    3. oxidative phosphorylation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Surfeit locus protein 1
    Gene namesi
    Name:Surf1
    Synonyms:Surf-1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:98443. Surf1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell
    3. mitochondrion Source: MGI

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306Surfeit locus protein 1PRO_0000215653Add
    BLAST

    Proteomic databases

    PaxDbiP09925.
    PRIDEiP09925.

    PTM databases

    PhosphoSiteiP09925.

    Expressioni

    Gene expression databases

    ArrayExpressiP09925.
    BgeeiP09925.
    CleanExiMM_SURF1.
    GenevestigatoriP09925.

    Structurei

    3D structure databases

    ProteinModelPortaliP09925.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei68 – 8619HelicalSequence AnalysisAdd
    BLAST
    Transmembranei280 – 30021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SURF1 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3346.
    GeneTreeiENSGT00530000064194.
    HOVERGENiHBG058486.
    InParanoidiP09925.
    KOiK14998.

    Family and domain databases

    InterProiIPR002994. Surf1/Shy1.
    [Graphical view]
    PfamiPF02104. SURF1. 1 hit.
    [Graphical view]
    PROSITEiPS50895. SURF1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P09925-1 [UniParc]FASTAAdd to Basket

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    MAAVMALAVL PRRMTRWSQW AYAGRAQFCA VRRSVFGFSV RSGMVCRPRR    50
    CCSSTAETAA AKAEDDSFLQ WFLLLIPATA FGLGTWQVQR RKWKLKLIAE 100
    LESRVMAEPI PLPADPMELK NLEYRPVKVR GHFDHSKELY IMPRTMVDPV 150
    REARDAGRLS STESGAHVVT PFHCSDLGVT ILVNRGFVPR KKVNPETRQK 200
    GQVLGEVDLV GIVRLTENRK PFVPENSPER NHWYYRDLEA MAKITGADPI 250
    FIDADFHSTA PGGPIGGQTR VTLRNEHMQY ILTWYGLCAA TSYLWFQKFV 300
    RRTPIM 306
    Length:306
    Mass (Da):34,798
    Last modified:June 6, 2002 - v3
    Checksum:i8D9ECE9FB726AEB7
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti9 – 91V → G in AAA40153. (PubMed:3025660)Curated
    Sequence conflicti14 – 141M → I in BAB22123. (PubMed:16141072)Curated
    Sequence conflicti284 – 2841W → CR in AAA40153. (PubMed:3025660)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M14689 Genomic DNA. Translation: AAA40153.1.
    AK002469 mRNA. Translation: BAB22123.1.
    BC004755 mRNA. Translation: AAH04755.1.
    CCDSiCCDS50543.1.
    PIRiB25394.
    RefSeqiNP_001258653.2. NM_001271724.1.
    NP_038705.2. NM_013677.2.
    UniGeneiMm.347512.

    Genome annotation databases

    EnsembliENSMUST00000167661; ENSMUSP00000128488; ENSMUSG00000015790.
    GeneIDi20930.
    KEGGimmu:20930.
    UCSCiuc008iwh.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M14689 Genomic DNA. Translation: AAA40153.1 .
    AK002469 mRNA. Translation: BAB22123.1 .
    BC004755 mRNA. Translation: AAH04755.1 .
    CCDSi CCDS50543.1.
    PIRi B25394.
    RefSeqi NP_001258653.2. NM_001271724.1.
    NP_038705.2. NM_013677.2.
    UniGenei Mm.347512.

    3D structure databases

    ProteinModelPortali P09925.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei P09925.

    Proteomic databases

    PaxDbi P09925.
    PRIDEi P09925.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000167661 ; ENSMUSP00000128488 ; ENSMUSG00000015790 .
    GeneIDi 20930.
    KEGGi mmu:20930.
    UCSCi uc008iwh.2. mouse.

    Organism-specific databases

    CTDi 6834.
    MGIi MGI:98443. Surf1.

    Phylogenomic databases

    eggNOGi COG3346.
    GeneTreei ENSGT00530000064194.
    HOVERGENi HBG058486.
    InParanoidi P09925.
    KOi K14998.

    Miscellaneous databases

    NextBioi 299855.
    PROi P09925.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P09925.
    Bgeei P09925.
    CleanExi MM_SURF1.
    Genevestigatori P09925.

    Family and domain databases

    InterProi IPR002994. Surf1/Shy1.
    [Graphical view ]
    Pfami PF02104. SURF1. 1 hit.
    [Graphical view ]
    PROSITEi PS50895. SURF1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units."
      Williams T.J., Fried M.
      Mol. Cell. Biol. 6:4558-4569(1986) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Fried M.
      Submitted (SEP-1988) to the EMBL/GenBank/DDBJ databases
      Cited for: SEQUENCE REVISION.
    3. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Kidney.
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiSURF1_MOUSE
    AccessioniPrimary (citable) accession number: P09925
    Secondary accession number(s): Q99KB4, Q9DCU5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: June 6, 2002
    Last modified: October 1, 2014
    This is version 110 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3