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P09925

- SURF1_MOUSE

UniProt

P09925 - SURF1_MOUSE

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Protein

Surfeit locus protein 1

Gene

Surf1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Probably involved in the biogenesis of the COX complex.By similarity

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: MGI

GO - Biological processi

  1. hydrogen ion transmembrane transport Source: GOC
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_262523. Respiratory electron transport.
REACT_268398. Orphan transporters.

Names & Taxonomyi

Protein namesi
Recommended name:
Surfeit locus protein 1
Gene namesi
Name:Surf1
Synonyms:Surf-1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:98443. Surf1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei68 – 8619HelicalSequence AnalysisAdd
BLAST
Transmembranei280 – 30021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
  3. mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Surfeit locus protein 1PRO_0000215653Add
BLAST

Proteomic databases

MaxQBiP09925.
PaxDbiP09925.
PRIDEiP09925.

PTM databases

PhosphoSiteiP09925.

Expressioni

Gene expression databases

BgeeiP09925.
CleanExiMM_SURF1.
ExpressionAtlasiP09925. baseline and differential.
GenevestigatoriP09925.

Structurei

3D structure databases

ProteinModelPortaliP09925.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SURF1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3346.
GeneTreeiENSGT00530000064194.
HOVERGENiHBG058486.
InParanoidiP09925.
KOiK14998.

Family and domain databases

InterProiIPR002994. Surf1/Shy1.
[Graphical view]
PfamiPF02104. SURF1. 1 hit.
[Graphical view]
PROSITEiPS50895. SURF1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P09925-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAVMALAVL PRRMTRWSQW AYAGRAQFCA VRRSVFGFSV RSGMVCRPRR
60 70 80 90 100
CCSSTAETAA AKAEDDSFLQ WFLLLIPATA FGLGTWQVQR RKWKLKLIAE
110 120 130 140 150
LESRVMAEPI PLPADPMELK NLEYRPVKVR GHFDHSKELY IMPRTMVDPV
160 170 180 190 200
REARDAGRLS STESGAHVVT PFHCSDLGVT ILVNRGFVPR KKVNPETRQK
210 220 230 240 250
GQVLGEVDLV GIVRLTENRK PFVPENSPER NHWYYRDLEA MAKITGADPI
260 270 280 290 300
FIDADFHSTA PGGPIGGQTR VTLRNEHMQY ILTWYGLCAA TSYLWFQKFV

RRTPIM
Length:306
Mass (Da):34,798
Last modified:June 6, 2002 - v3
Checksum:i8D9ECE9FB726AEB7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti9 – 91V → G in AAA40153. (PubMed:3025660)Curated
Sequence conflicti14 – 141M → I in BAB22123. (PubMed:16141072)Curated
Sequence conflicti284 – 2841W → CR in AAA40153. (PubMed:3025660)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14689 Genomic DNA. Translation: AAA40153.1.
AK002469 mRNA. Translation: BAB22123.1.
BC004755 mRNA. Translation: AAH04755.1.
CCDSiCCDS50543.1.
PIRiB25394.
RefSeqiNP_001258653.2. NM_001271724.1.
NP_038705.2. NM_013677.2.
UniGeneiMm.347512.

Genome annotation databases

EnsembliENSMUST00000167661; ENSMUSP00000128488; ENSMUSG00000015790.
GeneIDi20930.
KEGGimmu:20930.
UCSCiuc008iwh.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14689 Genomic DNA. Translation: AAA40153.1 .
AK002469 mRNA. Translation: BAB22123.1 .
BC004755 mRNA. Translation: AAH04755.1 .
CCDSi CCDS50543.1.
PIRi B25394.
RefSeqi NP_001258653.2. NM_001271724.1.
NP_038705.2. NM_013677.2.
UniGenei Mm.347512.

3D structure databases

ProteinModelPortali P09925.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei P09925.

Proteomic databases

MaxQBi P09925.
PaxDbi P09925.
PRIDEi P09925.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000167661 ; ENSMUSP00000128488 ; ENSMUSG00000015790 .
GeneIDi 20930.
KEGGi mmu:20930.
UCSCi uc008iwh.2. mouse.

Organism-specific databases

CTDi 6834.
MGIi MGI:98443. Surf1.

Phylogenomic databases

eggNOGi COG3346.
GeneTreei ENSGT00530000064194.
HOVERGENi HBG058486.
InParanoidi P09925.
KOi K14998.

Enzyme and pathway databases

Reactomei REACT_262523. Respiratory electron transport.
REACT_268398. Orphan transporters.

Miscellaneous databases

NextBioi 299855.
PROi P09925.
SOURCEi Search...

Gene expression databases

Bgeei P09925.
CleanExi MM_SURF1.
ExpressionAtlasi P09925. baseline and differential.
Genevestigatori P09925.

Family and domain databases

InterProi IPR002994. Surf1/Shy1.
[Graphical view ]
Pfami PF02104. SURF1. 1 hit.
[Graphical view ]
PROSITEi PS50895. SURF1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units."
    Williams T.J., Fried M.
    Mol. Cell. Biol. 6:4558-4569(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Fried M.
    Submitted (SEP-1988) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Kidney.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiSURF1_MOUSE
AccessioniPrimary (citable) accession number: P09925
Secondary accession number(s): Q99KB4, Q9DCU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: June 6, 2002
Last modified: November 26, 2014
This is version 112 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3