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P09925

- SURF1_MOUSE

UniProt

P09925 - SURF1_MOUSE

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Protein

Surfeit locus protein 1

Gene
Surf1, Surf-1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Probably involved in the biogenesis of the COX complex By similarity.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: MGI

GO - Biological processi

  1. ATP biosynthetic process Source: Ensembl
  2. hydrogen ion transmembrane transport Source: GOC
  3. oxidative phosphorylation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Surfeit locus protein 1
Gene namesi
Name:Surf1
Synonyms:Surf-1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:98443. Surf1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei68 – 8619Helical; Reviewed predictionAdd
BLAST
Transmembranei280 – 30021Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
  3. mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Surfeit locus protein 1PRO_0000215653Add
BLAST

Proteomic databases

PaxDbiP09925.
PRIDEiP09925.

PTM databases

PhosphoSiteiP09925.

Expressioni

Gene expression databases

ArrayExpressiP09925.
BgeeiP09925.
CleanExiMM_SURF1.
GenevestigatoriP09925.

Structurei

3D structure databases

ProteinModelPortaliP09925.

Family & Domainsi

Sequence similaritiesi

Belongs to the SURF1 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3346.
GeneTreeiENSGT00530000064194.
HOVERGENiHBG058486.
InParanoidiP09925.
KOiK14998.

Family and domain databases

InterProiIPR002994. Surf1/Shy1.
[Graphical view]
PfamiPF02104. SURF1. 1 hit.
[Graphical view]
PROSITEiPS50895. SURF1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P09925-1 [UniParc]FASTAAdd to Basket

« Hide

MAAVMALAVL PRRMTRWSQW AYAGRAQFCA VRRSVFGFSV RSGMVCRPRR    50
CCSSTAETAA AKAEDDSFLQ WFLLLIPATA FGLGTWQVQR RKWKLKLIAE 100
LESRVMAEPI PLPADPMELK NLEYRPVKVR GHFDHSKELY IMPRTMVDPV 150
REARDAGRLS STESGAHVVT PFHCSDLGVT ILVNRGFVPR KKVNPETRQK 200
GQVLGEVDLV GIVRLTENRK PFVPENSPER NHWYYRDLEA MAKITGADPI 250
FIDADFHSTA PGGPIGGQTR VTLRNEHMQY ILTWYGLCAA TSYLWFQKFV 300
RRTPIM 306
Length:306
Mass (Da):34,798
Last modified:June 6, 2002 - v3
Checksum:i8D9ECE9FB726AEB7
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti9 – 91V → G in AAA40153. 1 Publication
Sequence conflicti14 – 141M → I in BAB22123. 1 Publication
Sequence conflicti284 – 2841W → CR in AAA40153. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M14689 Genomic DNA. Translation: AAA40153.1.
AK002469 mRNA. Translation: BAB22123.1.
BC004755 mRNA. Translation: AAH04755.1.
CCDSiCCDS50543.1.
PIRiB25394.
RefSeqiNP_001258653.2. NM_001271724.1.
NP_038705.2. NM_013677.2.
UniGeneiMm.347512.

Genome annotation databases

EnsembliENSMUST00000167661; ENSMUSP00000128488; ENSMUSG00000015790.
GeneIDi20930.
KEGGimmu:20930.
UCSCiuc008iwh.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M14689 Genomic DNA. Translation: AAA40153.1 .
AK002469 mRNA. Translation: BAB22123.1 .
BC004755 mRNA. Translation: AAH04755.1 .
CCDSi CCDS50543.1.
PIRi B25394.
RefSeqi NP_001258653.2. NM_001271724.1.
NP_038705.2. NM_013677.2.
UniGenei Mm.347512.

3D structure databases

ProteinModelPortali P09925.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei P09925.

Proteomic databases

PaxDbi P09925.
PRIDEi P09925.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000167661 ; ENSMUSP00000128488 ; ENSMUSG00000015790 .
GeneIDi 20930.
KEGGi mmu:20930.
UCSCi uc008iwh.2. mouse.

Organism-specific databases

CTDi 6834.
MGIi MGI:98443. Surf1.

Phylogenomic databases

eggNOGi COG3346.
GeneTreei ENSGT00530000064194.
HOVERGENi HBG058486.
InParanoidi P09925.
KOi K14998.

Miscellaneous databases

NextBioi 299855.
PROi P09925.
SOURCEi Search...

Gene expression databases

ArrayExpressi P09925.
Bgeei P09925.
CleanExi MM_SURF1.
Genevestigatori P09925.

Family and domain databases

InterProi IPR002994. Surf1/Shy1.
[Graphical view ]
Pfami PF02104. SURF1. 1 hit.
[Graphical view ]
PROSITEi PS50895. SURF1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units."
    Williams T.J., Fried M.
    Mol. Cell. Biol. 6:4558-4569(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Fried M.
    Submitted (SEP-1988) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Kidney.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiSURF1_MOUSE
AccessioniPrimary (citable) accession number: P09925
Secondary accession number(s): Q99KB4, Q9DCU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: June 6, 2002
Last modified: July 9, 2014
This is version 109 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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