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Reviewed, UniProtKB/Swiss-Prot P09924 (DEOC_MYCPN)

Last modified November 24, 2009. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA
Gene names
Name: deoC
Ordered Locus Names: MPN_063
ORF Names: MP091
OrganismMycoplasma pneumoniae [Complete proteome] [HAMAP]
Taxonomic identifier2104 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

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Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

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Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate catabolic process

Inferred from electronic annotation. Source: HAMAP

deoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 224224Deoxyribose-phosphate aldolase HAMAP MF_00114
PRO_0000057245

Sites

Active site1521Schiff-base intermediate with acetaldehyde By similarity
Active site1811 By similarity

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Sequences

Sequence LengthMass (Da)Tools
P09924-1 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: 73C3E4932E7881F7

FASTA22424,878
        10         20         30         40         50         60 
MKLEYNRIID STLLKADTLP HEIDALCADA HKYQFYAVCV NPSYVRYAKN ILKGTGVKLC 

        70         80         90        100        110        120 
TVVGFPLGQT TQRQKVYETK IAIKEGADEI DMVMNIAEFK KRCACVISEI RAVKKVCGKR 

       130        140        150        160        170        180 
TLKVIIETAL LNQDEIRDAV NVCIDGNADF VKTSTGFSMR GASLEDITIM REASGNLIKI 

       190        200        210        220 
KASGGVQTAQ QFLDFFNAGV SRIGTSNAVK IMEELHKLES HEHR

« Hide

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References

« Hide 'large scale' references
[1]"Nucleotide sequence of the deoC gene of Mycoplasma pneumoniae."
Loechel S., Inamine J.M., Hu P.-C.
Nucleic Acids Res. 17:801-801(1989) [PubMed: 2492658] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 29342 / M129.
[2]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

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Cross-references

Sequence databases

X13544 Genomic DNA. Translation: CAA31897.1.
U00089 Genomic DNA. Translation: AAB95739.1.
PIRS02216.
RefSeqNP_109751.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID876837.
GenomeReviewsGene locus MPN_063 in contig U00089_GR.
KEGGmpn:MPN063.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP09924.
OMACLEAREN

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-641.
MPNE272634:MPN063-MON.
BRENDA4.1.2.4. 39500.

Family and domain databases

HAMAPMF_00114.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. deoC. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameDEOC_MYCPN
AccessionPrimary (citable) accession number: P09924
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: November 24, 2009
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents