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Protein

Modification methylase Rho11sI

Gene
N/A
Organism
Bacillus phage rho11s (Bacteriophage rho-11s)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This enzyme methylates cytosine within the sequences GGCC and GAGCTC.

Catalytic activityi

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei78PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processRestriction system
LigandS-adenosyl-L-methionine

Protein family/group databases

REBASEi2835 M.Rho11sI

Names & Taxonomyi

Protein namesi
Recommended name:
Modification methylase Rho11sI (EC:2.1.1.37)
Short name:
M.Rho11sI
Alternative name(s):
Bsu P11s
Cytosine-specific methyltransferase Rho11sI
OrganismiBacillus phage rho11s (Bacteriophage rho-11s)
Taxonomic identifieri10735 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeLambdavirusunclassified Lambda-like viruses
Virus hostiBacillus subtilis [TaxID: 1423]

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000878691 – 503Modification methylase Rho11sIAdd BLAST503

Structurei

3D structure databases

ProteinModelPortaliP09915
SMRiP09915
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 500SAM-dependent MTase C5-typePROSITE-ProRule annotationAdd BLAST497

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR018117 C5_DNA_meth_AS
IPR001525 C5_MeTfrase
IPR031303 C5_meth_CS
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF00145 DNA_methylase, 1 hit
PRINTSiPR00105 C5METTRFRASE
SUPFAMiSSF53335 SSF53335, 4 hits
TIGRFAMsiTIGR00675 dcm, 1 hit
PROSITEiView protein in PROSITE
PS00094 C5_MTASE_1, 1 hit
PS00095 C5_MTASE_2, 1 hit
PS51679 SAM_MT_C5, 1 hit

Sequencei

Sequence statusi: Complete.

P09915-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLRVMSLF SGIGAFEAAL RNIGVEYELV GFSEIDKYAI KSYCAIHNAD
60 70 80 90 100
EQLNFGDVSK IDKKKLPEFD LLVGGSPCQS FSVAGYRKGF EDTRGTLFFQ
110 120 130 140 150
YIDTLKEKQP RYFVFENVKG LINHDKGNTL NIMAESFSEV GYRIDLELLN
160 170 180 190 200
SKFFNVPQNR ERIYIIGVRE DLIENDEWVV EKGRNDVLSK GKKRLKELNI
210 220 230 240 250
KSFNFKWSAQ DIVGRRLREI LEEYVDEKYY LSEEKTSKLI EQIEKPKEKD
260 270 280 290 300
VVFVGGINVG KRWLNNGKTY SRNFKQGNRV YDSNGIATTL TSQSVGGLGG
310 320 330 340 350
QTSLYKVEDP IMIGHIDLKG HDAIKRVYSP DGVSPTLTTM GEGHREPKIA
360 370 380 390 400
VEYVGNINPS GKGMNDQVYN SNGLSPTLTT NKGEGVKISV PNPEIRPVLT
410 420 430 440 450
PEREEKRQNG RRFKEDDEPA FTVNTIDRHG VAIGEYPKYR IRKLTPLECW
460 470 480 490 500
RLQAFDEEDF EKALSVGISN SQLYKQAGNS ITVTVLESIF KELIHTYVNE

ESE
Length:503
Mass (Da):57,130
Last modified:November 1, 1995 - v2
Checksum:iAAAFB8FE01B8129E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05242 Genomic DNA Translation: CAA28869.1
PIRiA28137 CTBPRH

Similar proteinsi

Entry informationi

Entry nameiMTBR_BPRH1
AccessioniPrimary (citable) accession number: P09915
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health