ID   ANTR_CHICK              Reviewed;         105 AA.
AC   P09859;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 3.
DT   16-JUN-2009, entry version 59.
DE   RecName: Full=Gastrin/cholecystokinin-like peptide;
DE   AltName: Full=Antral peptide;
DE   Flags: Precursor;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;
OC   Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   MEDLINE=95331277; PubMed=7607213;
RX   DOI=10.1111/j.1432-1033.1995.0439h.x;
RA   Wu S.V., Dimaline R., Walsh J.H., Campbell B.J.;
RT   "Molecular characterization and physiological regulation of a TATA-
RT   less gene encoding chicken gastrin.";
RL   Eur. J. Biochem. 230:439-446(1995).
RN   [2]
RP   PROTEIN SEQUENCE OF 41-93.
RC   TISSUE=Gastric antrum;
RX   MEDLINE=92396616; PubMed=1523171; DOI=10.1016/0196-9781(92)90095-K;
RA   Bjoernskov I., Rehfeld J.F., Johnsen A.H.;
RT   "Identification of four chicken gastrins, obtained by processing at
RT   post-Phe bonds.";
RL   Peptides 13:595-601(1992).
RN   [3]
RP   PROTEIN SEQUENCE OF 58-93.
RC   TISSUE=Gastric antrum;
RX   MEDLINE=86301173; PubMed=3743781; DOI=10.1016/0014-5793(86)80920-6;
RA   Dimaline R., Young J., Gregory H.;
RT   "Isolation from chicken antrum, and primary amino acid sequence of a
RT   novel 36-residue peptide of the gastrin/CCK family.";
RL   FEBS Lett. 205:318-322(1986).
CC   -!- FUNCTION: Potent stimulus of gastric acid, but not of pancreatic
CC       secretion.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the gastrin/cholecystokinin family.
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DR   EMBL; U25125; AAA65926.1; -; Genomic_DNA.
DR   EMBL; U25124; AAA65925.1; -; mRNA.
DR   IPI; IPI00603959; -.
DR   PIR; S65677; S65677.
DR   RefSeq; NP_990731.1; -.
DR   UniGene; Gga.782; -.
DR   GeneID; 396365; -.
DR   KEGG; gga:396365; -.
DR   HOVERGEN; P09859; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR   InterPro; IPR001651; Gastrin.
DR   InterPro; IPR013152; Gastrin/cholecystokinin_CS.
DR   Pfam; PF00918; Gastrin; 1.
DR   SMART; SM00029; GASTRIN; 1.
DR   PROSITE; PS00259; GASTRIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Cleavage on pair of basic residues; Digestion;
KW   Direct protein sequencing; Hormone; Secreted; Signal; Sulfation.
FT   SIGNAL        1     20       Potential.
FT   PROPEP       21     38
FT                                /FTId=PRO_0000010656.
FT   PEPTIDE      41     93       Gastrin/cholecystokinin-like peptide.
FT                                /FTId=PRO_0000010657.
FT   PROPEP       97    105
FT                                /FTId=PRO_0000010658.
FT   MOD_RES      87     87       Sulfotyrosine.
FT   MOD_RES      93     93       Phenylalanine amide.
SQ   SEQUENCE   105 AA;  11625 MW;  9DB4B005EBD931DC CRC64;
     MKTKVFLGLI LSAAVTACLC RPAAKAPGGS HRPTSSLARR DWPEPPSQEQ QQRFISRFLP
     HVFAELSDRK GFVQGNGAVE ALHDHFYPDW MDFGRRSTED AADAA
//