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Protein

4-cresol dehydrogenase [hydroxylating] cytochrome c subunit

Gene

pchC

Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

This is the heme-containing component of the p-cresol methylhydroxylase. It accepts electrons from the flavoprotein subunit.

Pathwayi: p-cresol degradation

This protein is involved in the pathway p-cresol degradation, which is part of Aromatic compound metabolism.
View all proteins of this organism that are known to be involved in the pathway p-cresol degradation and in Aromatic compound metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei48 – 481Heme (covalent)
Binding sitei51 – 511Heme (covalent)
Metal bindingi52 – 521Iron (heme axial ligand)
Metal bindingi83 – 831Iron (heme axial ligand)

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00708.

Names & Taxonomyi

Protein namesi
Recommended name:
4-cresol dehydrogenase [hydroxylating] cytochrome c subunit
Alternative name(s):
Flavocytochrome c
P-cresol methylhydroxylase cytochrome subunit
Gene namesi
Name:pchC
Encoded oniPlasmid pRA40002 Publications
Plasmid pRA5005 Publications
OrganismiPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifieri303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 33331 PublicationAdd
BLAST
Chaini34 – 113804-cresol dehydrogenase [hydroxylating] cytochrome c subunitPRO_0000006567Add
BLAST

Post-translational modificationi

Binds 1 heme group per subunit.

Interactioni

Subunit structurei

Tetramer of two cytochrome subunits and two flavoprotein subunits.

Protein-protein interaction databases

IntActiP09787. 1 interaction.

Structurei

Secondary structure

1
113
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi37 – 393Combined sources
Helixi40 – 467Combined sources
Helixi49 – 524Combined sources
Turni54 – 563Combined sources
Helixi69 – 7810Combined sources
Turni88 – 903Combined sources
Helixi93 – 10513Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1DIIX-ray2.50C/D34-113[»]
1DIQX-ray2.75C/D34-113[»]
1WVEX-ray1.85C/D34-113[»]
ProteinModelPortaliP09787.
SMRiP09787. Positions 35-109.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP09787.

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
[Graphical view]
PfamiPF13442. Cytochrome_CBB3. 1 hit.
[Graphical view]
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P09787-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFPFSGAAV KRMLVTGVVL PFGLLVAAGQ AQADSQWGSG KNLYDKVCGH
60 70 80 90 100
CHKPEVGVGP VLEGRGLPEA YIKDIVRNGF RAMPAFPASY VDDESLTQVA
110
EYLSSLPAPA AQP
Length:113
Mass (Da):11,934
Last modified:November 16, 2001 - v2
Checksum:i568ED7438521C1E1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti111 – 1111Missing AA sequence (PubMed:3790500).Curated
Sequence conflicti113 – 1131Missing AA sequence (PubMed:3790500).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti74 – 741D → A in strain: NCIMB 9866.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U96339 Genomic DNA. Translation: AAA80317.2.
U96338 Genomic DNA. Translation: AAA80319.2.
PIRiT46685.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U96339 Genomic DNA. Translation: AAA80317.2.
U96338 Genomic DNA. Translation: AAA80319.2.
PIRiT46685.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1DIIX-ray2.50C/D34-113[»]
1DIQX-ray2.75C/D34-113[»]
1WVEX-ray1.85C/D34-113[»]
ProteinModelPortaliP09787.
SMRiP09787. Positions 35-109.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP09787. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00708.

Miscellaneous databases

EvolutionaryTraceiP09787.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
[Graphical view]
PfamiPF13442. Cytochrome_CBB3. 1 hit.
[Graphical view]
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCY4C_PSEPU
AccessioniPrimary (citable) accession number: P09787
Secondary accession number(s): Q59698, Q59707
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: November 16, 2001
Last modified: May 11, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Plasmid

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.